Malignant Solid Neoplasm Clinical Trials in Rochester, Minnesota

21 studies are recruiting for malignant solid neoplasm in Rochester, Minnesota right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

   This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positive solid tumors. Neratinib and palbociclib are in a class of medications called kinase inhibitors. They work by blocking the action of an ab…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   194 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT06126276 on ClinicalTrials.gov

2. Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

   This study collects research data and samples from patients who experience immunotherapy side effects to store for use in future research studies. Studying research data and samples from patients who experience immunotherapy side effects may help researchers better understand how to predict, preven…

   Stage

   Not phased

   Ages

   Any age

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   625 in total

   Run by

   Alliance for Clinical Trials in Oncology

   See if you can join NCT04242095 on ClinicalTrials.gov

3. A Novel Molecular Approach to Blood DNA Screening for Cancer: Specificity Assessment (The NOMAD Study)

   This study is being done to establish "normal' values for a new blood test and urine test approach to cancer screening. Patients undergo blood and urine sample collection on study. Patients' medical records are reviewed.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06192875 on ClinicalTrials.gov

4. Project: Every Child for Younger Patients With Cancer

   This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

   Stage

   Not phased

   Ages

   Up to 25

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   279 in total

   Run by

   Children's Oncology Group

   See if you can join NCT02402244 on ClinicalTrials.gov

5. Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

   This study explores the potential value of a new blood test approach for early detection of cancer.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06304168 on ClinicalTrials.gov

6. Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

   This phase III trial studies the side effects and how well stereotactic radiosurgery (SRS) works before or after surgery in patients with tumors that has spread to the brain or that can be removed by surgery. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high …

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   4 in total

   Run by

   Mayo Clinic

   See if you can join NCT03750227 on ClinicalTrials.gov

7. Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

   This study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   4 in total

   Run by

   Mayo Clinic

   See if you can join NCT06353191 on ClinicalTrials.gov

8. Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy

   This study examines how spinal cord stimulation (SCS) affects pain level and quality of life in patients experiencing chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a nerve problem and one of the potential side effects of chemotherapy that causes pain, numbness, tingling, swelling, or m…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT05411523 on ClinicalTrials.gov

9. Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning

   This study measures the utility of a novel artificial intelligence (AI) algorithm for performing auto-segmentation of computed tomography (CT) scans for radiation therapy planning.

   Stage

   Not phased

   Ages

   Any age

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Locations

   7 in total

   Run by

   Mayo Clinic

   See if you can join NCT06200116 on ClinicalTrials.gov

10. Impact of Physician Behavior on Cancer Distress

    This evaluates the impact of physician behaviors and other factors experienced during radiation treatment influence distress levels in cancer patients.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT07325006 on ClinicalTrials.gov

11. A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota

    This clinical trial evaluates whether a virtual stress reduction program that uses mindfulness-based stress reduction (MBSR) techniques works to improve mental health outcomes in cancer patients living in underserved/rural regions of Minnesota. 80% of Minnesota counties are considered mental health…

    Stage

    Not phased

    Ages

    Any age

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT07291011 on ClinicalTrials.gov

12. Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

    This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06788886 on ClinicalTrials.gov

13. Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients

    This clinical trial tests how well cognitive behavioral cancer stress management (CBCSM) group sessions work to decrease psychological distress in cancer patients. CBCSM teaches patients how to recognize and reduce the impacts of cancer associated stress on the biological, psychological, and social…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06015932 on ClinicalTrials.gov

14. Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

    This clinicaI trial is being done to determine if acupressure is helpful to reduce anxiety related to chemotherapy, compared with "sham" (or placebo) acupressure in patients with cancer. Anxiety, experienced by many patients with cancer, can be related to chemotherapy and may contribute to other sy…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06723041 on ClinicalTrials.gov

15. INTERogating Cancer for Etiology, Prevention and Therapy Navigation

    This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Locations

    3 in total

    Run by

    Mayo Clinic

    See if you can join NCT06008392 on ClinicalTrials.gov

16. Wisconsin Ginseng for Decreasing Cancer Related Fatigue

    This phase III trial compares the effect of Wisconsin ginseng (panax quinquefolius) to placebo in patients with cancer that suffer from significant fatigue. Fatigue is among the most challenging symptoms to manage in patients with cancer, both on or off active treatment. This symptom complex meanin…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Locations

    15 in total

    Run by

    Mayo Clinic

    See if you can join NCT06395441 on ClinicalTrials.gov

17. Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial

    This clinical trial tests the feasibility, usability and acceptability of a virtual art therapy assisted re-integration (AVATARS) intervention to improve biopsychosocial outcomes, such as anxiety, depression, resilience, emotional regulation, stress, and cognition, among adolescent and young adult …

    Stage

    Not phased

    Ages

    10 to 25

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Locations

    2 in total

    Run by

    Mayo Clinic

    See if you can join NCT07089927 on ClinicalTrials.gov

18. Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer

    This study uses ambient sensing rooms to collect data from hospitalized cancer patients in order to improve safety and recovery. Being hospitalized increases the risk for delirium (acute confusion), falls, troubles sleeping, and mood changes. Ambient sensing rooms are special rooms that use technol…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT07477886 on ClinicalTrials.gov

19. Role of Gut Microbiome in Cancer Therapy

    This study examines how gut microbiome can affect cancer therapy in cancer patients undergoing cancer therapy or stem cell transplant. The human microbiome affects the way some cancer drugs are metabolized in the human body. Information from this study may help doctors improve the way cancer treatm…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Locations

    3 in total

    Run by

    Mayo Clinic

    See if you can join NCT05112614 on ClinicalTrials.gov

20. Collection and Storage of Tissue and Blood Samples From Patients With Cancer

    This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

    Stage

    Not phased

    Ages

    0 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Locations

    140 in total

    Run by

    National Cancer Institute LAO

    See if you can join NCT02474160 on ClinicalTrials.gov

21. Voices: Messages of Wisdom and Hope in the Face of Illness

    This study may help doctors determine where patients and caregivers may need more support and identify ways to maintain patient and caregiver dignity while undergoing treatment.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT07381179 on ClinicalTrials.gov