Kidney Transplant Clinical Trials

15 studies are recruiting for kidney transplant in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Advancing Transplantation Outcomes in Children

   This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant pr…

   Stage

   Phase 2

   Ages

   13 to 20

   Site

   University of Alabama at Birmingham (Site # 71038), Birmingham, Alabama

   Locations

   21 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06055608 on ClinicalTrials.gov

2. A Trial to Evaluate the Safety, Tolerability and Efficacy of AIC263029 in Kidney Transplant Recipients With BKV Infection

   The goal of this clinical trial is to learn if AIC263029 is safe and well tolerated in adult kidney transplant recipients with BK virus (BKV) in the blood (viremia). The study will also examine how the body processes AIC263029 and whether it lowers BKV levels in the blood. Researchers will compare …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Alabama at Birmingham Hospital, Birmingham, Alabama

   Locations

   7 in total

   Run by

   AiCuris Anti-infective Cures AG

   See if you can join NCT07503561 on ClinicalTrials.gov

3. Social Support Counseling Intervention for Kidney Transplant Candidates

   Virtual Coaching for Potential Kidney Transplant Patients

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hennepin Healthcare, Minneapolis, Minnesota

   Run by

   Hennepin Healthcare Research Institute

   See if you can join NCT06147076 on ClinicalTrials.gov

4. CAR-T Cell Therapy for Desensitization in Kidney Transplantation

   This research study is for people who have been waiting for a kidney transplant for at least one year, and who have a cPRA of 99.5% or higher. Having a cPRA of 99.5% or higher means that your immune system would reject 99.5% of kidneys available for transplant. The study will test whether new produ…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   Massachusetts General Hospital: Transplantation (Site #: 71107), Boston, Massachusetts

   Locations

   3 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06056102 on ClinicalTrials.gov

5. A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

   The purpose of this research is to collect blood samples and data from kidney transplant patients. The samples and data will be used for research and development of non-invasive test to detect donor-derived cell-free DNA (dd-cfDNA) in kidney transplant patients to evaluate the status of the transpl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Scripps Health, San Diego, California

   Locations

   6 in total

   Run by

   Devyser Inc.

   See if you can join NCT07006831 on ClinicalTrials.gov

6. Feasibility and Plausible Effectiveness of a Lifestyle Intervention in Kidney Transplant Recipients (HEAL)

   The goal of this clinical trial is to learn whether if it is feasible to implement a study of patients receiving kidney transplantation, to learn if these patients will complete selective outcomes measurements, and to examine if a lifestyle intervention may assist with preventing weight gain compar…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT06640179 on ClinicalTrials.gov

7. Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

   The primary objective of this study is to demonstrate the efficacy of ravulizumab vs placebo in reducing the severity of DGF as measured by time to freedom from dialysis in adult participants who are at high risk of DGF after undergoing transplant of deceased donor kidney.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Research Site, Phoenix, Arizona

   Locations

   130 in total

   Run by

   Alexion Pharmaceuticals, Inc.

   See if you can join NCT06830798 on ClinicalTrials.gov

8. Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

   The purpose of this study is to find out if an investigational treatment will allow kidney transplant recipients to better accept their new kidney and stop immunosuppressive medicines. This study is for kidney transplant recipients who receive a kidney from a sibling donor. The investigational trea…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of California, Los Angeles, Los Angeles, California

   Run by

   Jeffrey Veale, MD

   See if you can join NCT03707262 on ClinicalTrials.gov

9. Empagliflozin Treatment in Kidney Transplant Recipients

   Kidney transplantation improves the health and quality of life for those Veterans with end stage kidney disease (ESKD). While early patient and graft survival are excellent, long-term outcomes continue to be challenging. Patient death with existing kidney graft function occurs in about half of all …

   Stage

   Phase 4

   Ages

   19 and older

   Site

   Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois

   Locations

   5 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT06013865 on ClinicalTrials.gov

10. Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

    800 adult first time kidney transplant recipients will be enrolled in the Observational Study and followed to evaluate their Human Leukocyte Antigen (HLA)-DR/DQ molecular mismatch (mMM) score as a risk-stratifying prognostic biomarker. Six months after transplant the study will identify those who m…

    Stage

    Phase 2

    Ages

    18 to 70

    Site

    University of Alabama School of Medicine: Transplantation, Birmingham, Alabama

    Locations

    15 in total

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT05917522 on ClinicalTrials.gov

11. An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

    This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.

    Stage

    Phase 3

    Ages

    18 to 65

    Site

    Perelman Center for Advanced Medicine - Endocrinology, Philadelphia, Pennsylvania

    Locations

    7 in total

    Run by

    Vertex Pharmaceuticals Incorporated

    See if you can join NCT06832410 on ClinicalTrials.gov

12. Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)

    The purpose of this study is to find out if Berinert can improve kidney function in the first year after transplant and to find out what effects, good or bad, Berinert will have in the kidney recipient. This research study will compare Berinert to placebo. The placebo looks exactly like Berinert bu…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Cedars Sinai Medical Center, Los Angeles, California

    Locations

    4 in total

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT06919003 on ClinicalTrials.gov

13. Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)

    The purpose of this protocol is to treat an intermediate-sized population with chronic kidney disease (CKD) including kidney transplant recipients. The protocol uses allogeneic bone marrow-derived mesenchymal stem cells (MSCs). MSC infusion may be delivered 1) intravenous or 2) intravenous plus int…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mayo Clinic, Jacksonville, Florida

    Run by

    Mayo Clinic

    See if you can join NCT06752577 on ClinicalTrials.gov

14. The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

    People with chronic kidney disease (CKD) often experience faster aging of the heart and blood vessels, which raises the risk of heart problems beyond traditional factors like high blood pressure or cholesterol. One early sign is reduced blood flow in the tiny vessels that supply the heart, measured…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT07222683 on ClinicalTrials.gov

15. The KidneyCARE (Community Access to Research Equity) Study

    For chronic kidney disease (CKD), there is a lack of unique and powerful platform for patient engagement, research studies and public health advocacy work. The National kidney Foundation (NKF) launched the first nationwide registry for people at all stages and types of CKD, including people on dial…

    Stage

    Not phased

    Ages

    18 to 120

    Site

    Geisinger Clinic, Danville, Pennsylvania

    Run by

    Tufts Medical Center

    See if you can join NCT05497518 on ClinicalTrials.gov