Kidney Transplant Clinical Trials in Philadelphia, Pennsylvania

5 studies are recruiting for kidney transplant in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Advancing Transplantation Outcomes in Children

   This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant pr…

   Stage

   Phase 2

   Ages

   13 to 20

   Site

   Children's Hospital of Philadelphia (Site #: 71091), Philadelphia, Pennsylvania

   Locations

   21 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06055608 on ClinicalTrials.gov

2. CAR-T Cell Therapy for Desensitization in Kidney Transplantation

   This research study is for people who have been waiting for a kidney transplant for at least one year, and who have a cPRA of 99.5% or higher. Having a cPRA of 99.5% or higher means that your immune system would reject 99.5% of kidneys available for transplant. The study will test whether new produ…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   University of Pennsylvania Medical Center (Site #: 71111), Philadelphia, Pennsylvania

   Locations

   3 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06056102 on ClinicalTrials.gov

3. Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

   The primary objective of this study is to demonstrate the efficacy of ravulizumab vs placebo in reducing the severity of DGF as measured by time to freedom from dialysis in adult participants who are at high risk of DGF after undergoing transplant of deceased donor kidney.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Research Site, Philadelphia, Pennsylvania

   Locations

   130 in total

   Run by

   Alexion Pharmaceuticals, Inc.

   See if you can join NCT06830798 on ClinicalTrials.gov

4. Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

   800 adult first time kidney transplant recipients will be enrolled in the Observational Study and followed to evaluate their Human Leukocyte Antigen (HLA)-DR/DQ molecular mismatch (mMM) score as a risk-stratifying prognostic biomarker. Six months after transplant the study will identify those who m…

   Stage

   Phase 2

   Ages

   18 to 70

   Site

   University of Pennsylvania Medical Center: Transplantation, Philadelphia, Pennsylvania

   Locations

   15 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT05917522 on ClinicalTrials.gov

5. An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

   This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant.

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   Perelman Center for Advanced Medicine - Endocrinology, Philadelphia, Pennsylvania

   Locations

   7 in total

   Run by

   Vertex Pharmaceuticals Incorporated

   See if you can join NCT06832410 on ClinicalTrials.gov