Kidney Transplant Clinical Trials in Boston, Massachusetts

5 studies are recruiting for kidney transplant in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Advancing Transplantation Outcomes in Children

   This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant pr…

   Stage

   Phase 2

   Ages

   13 to 20

   Site

   Boston Children's Hospital (Site #: 71001), Boston, Massachusetts

   Locations

   21 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06055608 on ClinicalTrials.gov

2. CAR-T Cell Therapy for Desensitization in Kidney Transplantation

   This research study is for people who have been waiting for a kidney transplant for at least one year, and who have a cPRA of 99.5% or higher. Having a cPRA of 99.5% or higher means that your immune system would reject 99.5% of kidneys available for transplant. The study will test whether new produ…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   Massachusetts General Hospital: Transplantation (Site #: 71107), Boston, Massachusetts

   Locations

   3 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06056102 on ClinicalTrials.gov

3. A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

   The purpose of this research is to collect blood samples and data from kidney transplant patients. The samples and data will be used for research and development of non-invasive test to detect donor-derived cell-free DNA (dd-cfDNA) in kidney transplant patients to evaluate the status of the transpl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham & Women's Hospital, Boston, Massachusetts

   Locations

   6 in total

   Run by

   Devyser Inc.

   See if you can join NCT07006831 on ClinicalTrials.gov

4. Assessment of Biomarker-Guided CNI Substitution In Kidney Transplantation

   800 adult first time kidney transplant recipients will be enrolled in the Observational Study and followed to evaluate their Human Leukocyte Antigen (HLA)-DR/DQ molecular mismatch (mMM) score as a risk-stratifying prognostic biomarker. Six months after transplant the study will identify those who m…

   Stage

   Phase 2

   Ages

   18 to 70

   Site

   Massachusetts General Hospital: Transplantation, Boston, Massachusetts

   Locations

   15 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT05917522 on ClinicalTrials.gov

5. The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

   People with chronic kidney disease (CKD) often experience faster aging of the heart and blood vessels, which raises the risk of heart problems beyond traditional factors like high blood pressure or cholesterol. One early sign is reduced blood flow in the tiny vessels that supply the heart, measured…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT07222683 on ClinicalTrials.gov