Heart Failure Clinical Trials in Dallas, Texas

33 studies are recruiting for heart failure in Dallas, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

   The purpose of this study is to evaluate if Non-Ischemic Heart Preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport hearts for transplantation.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Texas Southwestern Medical Center, Dallas, Texas

   Locations

   14 in total

   Run by

   XVIVO Perfusion

   See if you can join NCT06895070 on ClinicalTrials.gov

2. Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

   The purpose of this research study is to determine the effectiveness of low dose colchicine (LoDoCo) on measures of exercise capacity, physical function, frailty, and quality of life, among patients with heart failure with chronic stable preserved ejection fraction (HFpEF) and systemic inflammation…

   Stage

   Phase 2

   Ages

   50 and older

   Site

   UT Southwestern Medical Center, Dallas, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT06130059 on ClinicalTrials.gov

3. Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

   This phase II, multi-center, open-label study will evaluate the safety and efficacy of utilizing HCV-positive donors for heart transplant in HCV-negative recipients treated with sofosbuvir 400 mg / velpatasvir 100 mg (Epclusa®).

   Stage

   Phase 2

   Ages

   18 to 90

   Site

   Baylor University Medical Center, Dallas, Texas

   Locations

   3 in total

   Run by

   Baylor Research Institute

   See if you can join NCT03383419 on ClinicalTrials.gov

4. Cardiopulmonary Stress Testing (CPET) AlloSure Study

   1. Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ. (The implication of the null result would be that no restrictions to patient activity, nor modification of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Baylor Scott & White health research institute, Dallas, Texas

   Run by

   Baylor Research Institute

   See if you can join NCT04656080 on ClinicalTrials.gov

5. Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

   This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure under…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas

   Locations

   3 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT04982419 on ClinicalTrials.gov

6. Get With The Guidelines-Heart Failure Registry

   Get With The Guidelines-Heart Failure is designed to improve the quality of care in patients hospitalized with heart failure. The program aims to help ensure that eligible patients are initiated on guideline recommended therapies and receive appropriate counseling prior to hospital discharge.

   Stage

   Not phased

   Ages

   18 to 125

   Site

   Amy Bennett, Dallas, Texas

   Run by

   American Heart Association

   See if you can join NCT02693509 on ClinicalTrials.gov

7. Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

   This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

   Stage

   Not phased

   Ages

   20 to 90

   Site

   UT Southwestern Medical Center, Dallas, Texas

   Locations

   3 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT01258231 on ClinicalTrials.gov

8. Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

   It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which will, in turn, translate to improved clinical outcomes. Additionally, it is hypothesized that corre…

   Stage

   Phase 1

   Ages

   18 to 80

   Site

   University of Texas Southwestern Medical Center, Dallas, Texas

   Locations

   5 in total

   Run by

   Sardocor Corp.

   See if you can join NCT04703842 on ClinicalTrials.gov