Heart Failure Clinical Trials in Boston, Massachusetts

33 studies are recruiting for heart failure in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

   The objective of this prospective, randomized, double- blinded (patient and assessors), sham-controlled clinical trial is to assess the safety and efficacy of the CMCS in treating heart failure with functional regurgitation (FMR).

   Stage

   Not phased

   Ages

   18 and older

   Site

   St Elizabeth's Medical Center, Boston, Massachusetts

   Locations

   92 in total

   Run by

   Cardiac Dimensions, Inc.

   See if you can join NCT03142152 on ClinicalTrials.gov

2. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

   Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 diabetes (T1D) remains unknown because …

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Joslin Diabetes Center, Boston, Massachusetts

   Locations

   19 in total

   Run by

   Alessandro Doria

   See if you can join NCT06217302 on ClinicalTrials.gov

3. Home Hospital for Suddenly Ill Adults

   The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be delivered in the home with equal quality and safety, reduced cost, and impro…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT03524222 on ClinicalTrials.gov

4. A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

   Severe skeletal wasting and catabolic weight loss are highly common among patients with heart failure with reduced ejection fraction (HFrEF). This prospective randomized controlled trial will compare changes in the muscle mass in the arms and the legs (appendicular lean mass) in patients with HFrEF…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   Tufts Medical Center, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Tufts Medical Center

   See if you can join NCT05627440 on ClinicalTrials.gov

5. Pulmonary Artery Catheter in Cardiogenic Shock Trial

   The primary objective of the PACCS trial is to assess if early invasive hemodynamic assessment and ongoing management with a PAC in patients with cardiogenic shock due to acutely decompensated heart failure (AHDF-CS) is associated with lower in-hospital mortality risk compared to the current standa…

   Stage

   Not phased

   Ages

   18 to 90

   Site

   Tufts Medical Center, Boston, Massachusetts

   Run by

   Tufts Medical Center

   See if you can join NCT05485376 on ClinicalTrials.gov

6. Left vs Left Randomized Clinical Trial

   The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications an…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   71 in total

   Run by

   Baylor College of Medicine

   See if you can join NCT05650658 on ClinicalTrials.gov

7. A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System

   The objective of this study is to evaluate the safety and performance of the V-LAP System in subjects with New York Heart Association (NYHA) functional class II and III HF, irrespective of left ventricular ejection fraction.

   Stage

   Not phased

   Ages

   22 to 88

   Site

   One Boston Medical Center Place, Boston, Massachusetts

   Run by

   Vectorious Medical Technologies Ltd.

   See if you can join NCT06147336 on ClinicalTrials.gov

8. Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

   This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

   Stage

   Not phased

   Ages

   20 to 90

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   3 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT01258231 on ClinicalTrials.gov