Crohn Disease Clinical Trials

37 studies are recruiting for crohn disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Effect of Statins on Crohn's Disease

   The goal of this clinical trial is to learn if statins work to prevent strictures in adults with Crohn's disease. The main question it aims to answer is: * Can statins reduce the formation of strictures in participants with stricturing Crohn's disease? Researchers will compare statins to a placebo …

   Stage

   EARLY_Phase 1

   Ages

   18 to 80

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT06538649 on ClinicalTrials.gov

2. Stem Cell Transplantation in Crohn's Disease

   Unfortunately, some patients with Crohn's disease (CD) fail to respond to the best clinical treatments and some only experience temporary benefit. For severe Crohn's disease, there is an experimental treatment called "high dose immunoablation" followed by autologous hematopoietic stem cell transpla…

   Stage

   Phase 1

   Ages

   13 to 28

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Run by

   Cedars-Sinai Medical Center

   See if you can join NCT04224558 on ClinicalTrials.gov

3. Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

   The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-Crohn's) tool on behaviors and biomarkers associated with risk for Crohn's disease in unaffected first-degree relatives of patients with inflammatory bowel…

   Stage

   Not phased

   Ages

   14 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05332639 on ClinicalTrials.gov

4. VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

   Transmural healing (TMH) is recognized as a potentially important measure of Crohn's disease (CD) activity but not a formal target. Observational studies suggest that TMH may be associated with better long-term outcomes. The study will evaluate TMH using noninvasive intestinal ultrasound (IUS), a p…

   Stage

   Phase 4

   Ages

   18 to 80

   Site

   Houston Methodist Hospital, Houston, Texas

   Locations

   69 in total

   Run by

   Alimentiv Inc.

   See if you can join NCT06257706 on ClinicalTrials.gov

5. A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

   The investigators have developed an inexpensive tool to take pictures in the lower GI tract without sedation and to look for signs of disease. The tool is a capsule, about the size of a fish oil or multi-vitamin supplement, attached to a string. The capsule and string are connected to a motor to al…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07219537 on ClinicalTrials.gov

6. Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

   The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-…

   Stage

   Not phased

   Ages

   13 to 20

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT04508088 on ClinicalTrials.gov

7. Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

   The goal of this research is to learn how a new device called the wireless thermal capsule (WTC) can collect thermal data to help see diseases that happen in the gastrointestinal (GI) tract, such as Crohn's Disease.

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07033208 on ClinicalTrials.gov

8. Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

   This study will compare the tolerability and efficacy of conventional formula Exclusive Enteral Nutrition (EEN) and whole-food blended smoothie EEN by enrolling a total of 60 participants with newly diagnosed pediatric Crohn's disease (CD). Participants will be provided either commercial formula or…

   Stage

   Not phased

   Ages

   8 to 21

   Site

   Seattle Children's Hospital, Seattle, Washington

   Locations

   3 in total

   Run by

   Seattle Children's Hospital

   See if you can join NCT06216899 on ClinicalTrials.gov

9. High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

   The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease. The investigators will be collecting some additional bloodwork and questionnaires at the time of participants infusions.

   Stage

   Not phased

   Ages

   5 to 25

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT04331639 on ClinicalTrials.gov

10. Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

    The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for one year after birth. With respect to fetal outcome, it…

    Stage

    Not phased

    Ages

    Any age

    Site

    University of California, San Diego, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT02103361 on ClinicalTrials.gov

11. Urine Metabolites in the Diagnosis of Disease

    The goal of this observational study is to validate a non-invasive, urine-based diagnostic technology for the detection and differentiation of various gastrointestinal (GI) diseases. This research study intends to enroll participants across a range of demographics and GI disease states including co…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Unio Health Partners (Gastroenterology), Encinitas, California

    Locations

    4 in total

    Run by

    Luventix, Inc.

    See if you can join NCT06710067 on ClinicalTrials.gov

12. Registry and Biorepository for IBD in Central Texas

    This is a prospective, non-interventional registry and biorepository for patients with IBD. Longitudinal follow-up data is collected from both patients and their treating gastroenterologist during routine clinical encounters. The biorepository will consist of prospective collection of blood samples…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Dell Medical School, UT Austin, Austin, Texas

    Run by

    University of Texas at Austin

    See if you can join NCT04617184 on ClinicalTrials.gov