Crohn Disease Clinical Trials in Chapel Hill, North Carolina

5 studies are recruiting for crohn disease in Chapel Hill, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

   The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a long-term condition causing severe inflammation of the intestinal tract).

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   370 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07196722 on ClinicalTrials.gov

2. A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

   The purpose of this study is to assess how well guselkumab works when compared to risankizumab in participants with moderately to severely active Crohn's Disease (CD; a long-term condition causing severe inflammation of the intestinal tract).

   Stage

   Phase 3

   Ages

   18 and older

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Locations

   160 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07499232 on ClinicalTrials.gov

3. A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

   The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active Crohn's disease (a long-term, progressive [worsens with time] and life-threatening disease of the intesti…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   University of North Carolina Hospital, Chapel Hill, North Carolina

   Locations

   142 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07577843 on ClinicalTrials.gov

4. A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

   The purpose of this post-marketing study is to assess the amount of guselkumab in breast milk of lactating women receiving guselkumab as part of their standard clinical care provided by their treating physician, for any of the approved indications.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07654751 on ClinicalTrials.gov

5. COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

   The purpose of the study is to compare the clinical effectiveness and safety of newer inflammatory bowel disease (IBD) medications in anti-tumor necrosis factor (TNF) refractory patients with pediatric IBD (PIBD). Refractory means that there was no clinical response to anti-tumor necrosis factor (T…

   Stage

   Not phased

   Ages

   1 to 18

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Locations

   4 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT07198113 on ClinicalTrials.gov