Crohn Disease Clinical Trials in Boston, Massachusetts

8 studies are recruiting for crohn disease in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

   This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Massachusetts General Hospital Cancer Center, Boston, Massachusetts

   Locations

   52 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT03816345 on ClinicalTrials.gov

2. Low Dose IL-2 for the Treatment of Crohn's Disease

   The purpose of this study is to determine the safety and maximum effective dose (MED) of Interleukin-2 in subjects with moderate-to-severe crohn's disease.

   Stage

   Phase 1

   Ages

   12 to 80

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Locations

   3 in total

   Run by

   Boston Children's Hospital

   See if you can join NCT04263831 on ClinicalTrials.gov

3. Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

   Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pain, diarrhea, blood in the stool, weight loss, or delayed growth in children. While the exact cause …

   Stage

   Phase 4

   Ages

   6 to 17

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Locations

   26 in total

   Run by

   Connecticut Children's Medical Center

   See if you can join NCT05781152 on ClinicalTrials.gov

4. Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

   The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-Crohn's) tool on behaviors and biomarkers associated with risk for Crohn's disease in unaffected first-degree relatives of patients with inflammatory bowel…

   Stage

   Not phased

   Ages

   14 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05332639 on ClinicalTrials.gov

5. A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

   The investigators have developed an inexpensive tool to take pictures in the lower GI tract without sedation and to look for signs of disease. The tool is a capsule, about the size of a fish oil or multi-vitamin supplement, attached to a string. The capsule and string are connected to a motor to al…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07219537 on ClinicalTrials.gov

6. Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

   The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-…

   Stage

   Not phased

   Ages

   13 to 20

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT04508088 on ClinicalTrials.gov

7. Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

   The goal of this research is to learn how a new device called the wireless thermal capsule (WTC) can collect thermal data to help see diseases that happen in the gastrointestinal (GI) tract, such as Crohn's Disease.

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07033208 on ClinicalTrials.gov

8. High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

   The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease. The investigators will be collecting some additional bloodwork and questionnaires at the time of participants infusions.

   Stage

   Not phased

   Ages

   5 to 25

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT04331639 on ClinicalTrials.gov