Breast Cancer Clinical Trials

414 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 9

1. Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

   This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-313 administered orally as a single agent or combination therapy in patients w…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Investigative Site #108, Goodyear, Arizona

   Locations

   18 in total

   Run by

   MOMA Therapeutics

   See if you can join NCT06545942 on ClinicalTrials.gov

2. The Florida ASCENT Study

   The goal of this clinical trial is to adapt, implement, and evaluate MyCarePulse and ASCENT patient navigator to overcome barriers to care among patients with cancer. The main hypotheses it aims to test are: * At the patient level, the intervention will result in higher levels of food security, sel…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT07042243 on ClinicalTrials.gov

3. Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors

   This study will explore whether tirzepatide is a practical and acceptable treatment for postmenopausal females with a history of hormone receptor-positive breast cancer and obesity. The investigators aim to understand whether participants are willing and able to take this medication once weekly for…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   Weill Cornell Medicine, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT07257484 on ClinicalTrials.gov

4. TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

   This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast cancer to receive all of their planned chemotherapy according to sched…

   Stage

   Not phased

   Ages

   65 and older

   Site

   Dana Farber Cancer Institute, Boston, Massachusetts

   Locations

   4 in total

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT05535192 on ClinicalTrials.gov

5. Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

   Breast-conserving surgery followed by re-irradiation with partial breast irradiation (rPBI) has recently been found to be a safe alternative to mastectomy for women who have undergone prior whole breast radiation. By reducing the volume of tissue receiving radiation, rPBI has been associated with l…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   NYU Langone Health, New York, New York

   Locations

   19 in total

   Run by

   University Health Network, Toronto

   See if you can join NCT05592938 on ClinicalTrials.gov

6. Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer

   This research study evaluates the effect of chemotherapy on cognition (thinking) and the brain in people with breast cancer.

   Stage

   Not phased

   Ages

   60 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT02290834 on ClinicalTrials.gov

7. The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts

   To learn whether a new imaging technology, Contrast-Enhanced Mammography (CEM), compared to standard mammography, can better detect breast cancers in women with dense breasts

   Stage

   Not phased

   Ages

   30 to 75

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT05667532 on ClinicalTrials.gov

8. Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

   This is a phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining the impact of riluzole therapy on circulating brain derived neuropathic factor (BDNF) levels in cancer survivors (recently completing prior treatment regimens) or patients who have received whole bra…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Chao Family Comprehensive Cancer Center, University of California Irvine, Orange, California

   Run by

   University of California, Irvine

   See if you can join NCT06580002 on ClinicalTrials.gov

9. PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival

   This is a hybrid decentralized, single-arm, interventional study designed to evaluate the impact of precision medicine navigation and reflexive expert review of next-generation sequencing (NGS) for patients with stage IV solid tumor malignancies (breast, lung, colorectal, and bladder cancers). The …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina

   Run by

   UNC Lineberger Comprehensive Cancer Center

   See if you can join NCT06896162 on ClinicalTrials.gov

10. Study to Evaluate the Feasibility of Twice Daily Use of Topical Azelaic Acid in Breast Cancer Patients Undergoing Radiation

    This pilot study will evaluate the feasibility of at least twice daily use of azelaic acid in breast cancer patients undergoing radiation treatment.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Virginia Commonwealth University, Richmond, Virginia

    Run by

    Virginia Commonwealth University

    See if you can join NCT06966388 on ClinicalTrials.gov

11. Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

    Checkpoint inhibitor therapy represents a significant advance in cancer care. The interaction between PD-1 and PD-L1 induces immune tolerance, and the inhibition of this interaction is an effective treatment strategy for numerous malignancies. Despite its demonstrated potential, immunotherapy is no…

    Stage

    Phase 1

    Ages

    18 to 99

    Site

    University of Florida, Gainesville, Florida

    Run by

    University of Florida

    See if you can join NCT05000294 on ClinicalTrials.gov

12. Screening For BCRL In Targeted Therapy For Breast Cancer

    This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer. A Perometer and Sozo devise will be used to measure volume changes

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT05142800 on ClinicalTrials.gov

13. Opioid Dispensing Device for Post-Operative Pain in Cancer Patients

    This research study will evaluate the use of, and participants experience with, a new device called Addinex that safely stores and dispenses opioid medication. The purpose of this study is to evaluate the use of the Addinex device in cancer patients undergoing cancer-related surgery that require pa…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Columbia University Medical Center, New York, New York

    Run by

    Columbia University

    See if you can join NCT05585788 on ClinicalTrials.gov

14. A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement

    The researchers are doing this study to find out whether Stimulan Rapid Cure works to reduce the risk of infections in people getting tissue expanders placed during mastectomy. The researchers will also study whether Stimulan Rapid Cure affects the risk of seroma, a possible complication of surgery…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

    Locations

    7 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT07220967 on ClinicalTrials.gov

15. Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD

    The purpose of this study is to learn about the effects of the study treatment, Dendritic Cell Vaccine (DCV), in combination with trastuzumab or nivolumab to confirm the highest dose of the study treatment that can be given safely to participants with Breast Cancer (BC) with Leptomeningeal Disease …

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Moffitt Cancer Center, Tampa, Florida

    Run by

    H. Lee Moffitt Cancer Center and Research Institute

    See if you can join NCT07694986 on ClinicalTrials.gov

16. A Study of a Decision Tool for People Considering Breast Reconstruction Surgery

    The purpose of this study is to find out whether it is practical (feasible) to do a larger study looking at the effectiveness of the Breast Reconstruction Decision Aid Tool (RECONJOINT) for breast reconstruction surgery.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

    Locations

    9 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT07335354 on ClinicalTrials.gov

17. Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

    This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-progressive solid tumors as the primary objective. The primary outcome measure is the time to treatment failure (defined as time to change i…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California, Davis, Sacramento, California

    Run by

    University of California, Davis

    See if you can join NCT06103669 on ClinicalTrials.gov

18. Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

    1. Efficacy of PULSAR preoperative radiation 2. Evaluate potential of microbubble CEUS as an alternative to operative SLNBx 3. Evaluate potential of OA to evaluate treatment response of pre-operative radiation on the tumor

    Stage

    Phase 2

    Ages

    18 and older

    Site

    UT Southwestern Medical Center-Dallas, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT06444269 on ClinicalTrials.gov

19. First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

    Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 (LY4064809) in participants with advanced solid tumors with P13Ka mutations. Part 1 will evaluate STX-478 as monotherap…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Ellison Clinic at Saint John's, Los Angeles, California

    Locations

    65 in total

    Run by

    Eli Lilly and Company

    See if you can join NCT05768139 on ClinicalTrials.gov

20. Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

    This is a post-marketing single arm, phase IV trial in which patients with high-risk early-stage HR+HER2- breast cancer will receive adjuvant abemaciclib in combination with endocrine therapy (ET) After study intervention, participants will remain on combination abemaciclib + ET at the discretion o…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of Illinois, Chicago, Illinois

    Locations

    3 in total

    Run by

    University of Illinois at Chicago

    See if you can join NCT06169371 on ClinicalTrials.gov

21. Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing

    Historically, serial testing of patients with metastatic breast cancer has included a combination of physical exam, symptom evaluation, laboratory testing, and imaging. Circulating tumor biomarkers are sometimes also incorporated. Frequent testing with numerous diagnostics at each time point is a s…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Washington University School of Medicine, St Louis, Missouri

    Run by

    Washington University School of Medicine

    See if you can join NCT04968964 on ClinicalTrials.gov

22. Navigation Intervention for Adolescent and Young Adult Cancer Survivors

    The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation trial of this program within Kaiser Permanente Southern California (KP…

    Stage

    Not phased

    Ages

    21 to 45

    Site

    KP Southern California - Department of Research & Evaluation, Pasadena, California

    Run by

    Kaiser Permanente

    See if you can join NCT07406087 on ClinicalTrials.gov

23. Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

    The primary objective of this pharmacokinetics study is to compare the maximum concentration level of paclitaxel in patients with low/sarcopenic skeletal muscle area (SMA), at the end of a 2-3 hour paclitaxel infusion, to the maximum level in patients with normal SMA at the end of a standard 1-hour…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of Michigan Rogel Cancer Center, Ann Arbor, Michigan

    Run by

    University of Michigan Rogel Cancer Center

    See if you can join NCT05183126 on ClinicalTrials.gov

24. Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer

    The purpose of the study is to determine the frequency of systemic metastasis in node positive breast cancer following chemotherapy and surgery. Participants will be asked to spend about 6 months in this study. Participants will undergo a computed tomography (CT) screening of the thorax, abdomen, a…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Moffitt Cancer Center, Tampa, Florida

    Run by

    H. Lee Moffitt Cancer Center and Research Institute

    See if you can join NCT06833502 on ClinicalTrials.gov

25. A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer

    The goal of this interventional study is to to evaluate the effectiveness and acceptability of a focused upper body massage when offered after radiation treatments to participants diagnosed with breast cancer. Given the prevalence of musculoskeletal complaints during radiation therapy delivery and …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University Comprehensive Cancer Center

    See if you can join NCT07447700 on ClinicalTrials.gov