Bladder Cancer Clinical Trials

86 studies are recruiting for bladder cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

   BCDx is a urine-based multi-omic assay for early cancer recurrence detection in patients with a history of bladder cancer. This prospective, blinded study evaluates its efficacy in detecting recurrent NMIBC, offering a noninvasive monitoring solution.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Arkansas Urology Research Center, Little Rock, Arkansas

   Locations

   3 in total

   Run by

   Early is Good Inc.

   See if you can join NCT05982561 on ClinicalTrials.gov

2. A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin Cancer

   The purpose of this study is to see whether 68Gallium PSMA-PET/CT scans are an effective way to detect sites of cancer in people with metastatic bladder cancer or skin cancer. The study researchers want to learn if a 68Gallium PSMA PET/CT scan will work better, the same, or not as well as the PET/C…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Memorial Sloan Kettering Basking Ridge (Consent Only), Basking Ridge, New Jersey

   Locations

   7 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT05562791 on ClinicalTrials.gov

3. Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

   The goal of this clinical trial is to learn whether a combination of two chemotherapy drugs, Gemcitabine and Docetaxel, can treat high-grade non-muscle-invasive bladder cancer (HG-NMIBC) in adults whose cancer failed conventional BCG therapy. The drugs are given directly into the bladder (intravesi…

   Stage

   Phase 2

   Ages

   18 to 99

   Site

   University of Iowa, Iowa City, Iowa

   Run by

   Michael A. O'Donnell

   See if you can join NCT07322263 on ClinicalTrials.gov

4. Metabolism Evaluation Through Resting Indirect Calorimetry in Bladder Cancer (METRICS)

   This study is being done to learn more about energy needs and muscle function during treatment for bladder cancer. These insights can help improve future patient care. The study team found in a previous study that resting energy can be different than what estimates show. Patients with bladder cance…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Locations

   2 in total

   Run by

   University of Kansas Medical Center

   See if you can join NCT06721260 on ClinicalTrials.gov

5. Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery

   In this 2-arm, non-randomized, phase II trial, the investigators will evaluate the efficacy and safety of comprehensive multimodal prehabilitation (CMMP) alone or in combination with planned neoadjuvant (NAT) in pre-frail/frail patients with probable/proven pancreaticobiliary, ovarian, kidney, or b…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Houston Methodist Neal Cancer Center, Houston, Texas

   Run by

   The Methodist Hospital Research Institute

   See if you can join NCT07050771 on ClinicalTrials.gov

6. Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder Cancer

   Bladder cancer is the 8th most common cancer in the UF Health Cancer Center catchment area and the 7th most common cancer presenting to UFHealth. Most newly diagnosed cases are stage I bladder cancer, which is defined by having no deep muscle invasion and no evidence of disease beyond the bladder. …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06488222 on ClinicalTrials.gov

7. Bladder Cancer Longitudinal Biorepository for Development of Novel Therapeutics/Biomarkers

   The purpose of this study is to create a registry, which is a "bank" of information about patients who have had similar medical conditions and treatments. The registry will be used by researchers to learn more about long term outcome of patients with bladder cancer, how bladder cancer tissues are r…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT03413982 on ClinicalTrials.gov

8. The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

   The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpos…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Allegheny Health Network, Pittsburgh, Pennsylvania

   Locations

   18 in total

   Run by

   UMC Utrecht

   See if you can join NCT04075305 on ClinicalTrials.gov

9. Telehealth Intervention for Ostomy Self-Management

   Over one million individuals in the U.S. have ostomies. An ostomy is a surgical procedure that creates an opening in the abdominal wall that allows bodily waste (urinary or fecal) to pass through into an external pouch; in essence, it is the externalization of the gastrointestinal or urinary struct…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   City of hope Medical Center, Duarte, California

   Run by

   City of Hope Medical Center

   See if you can join NCT06528990 on ClinicalTrials.gov

10. Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

    The goal of this clinical trial is to learn if an investigational drug CP-383 works to treat advanced cancer. It will also learn about the safety of CP-383. The main questions if aims to answer are: * Does CP-383 slow or stop the growth of cancer in patients with advanced cancer * What medical prob…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Sarah Cannon Research Institute at HealthONE, Denver, Colorado

    Locations

    13 in total

    Run by

    Tasca Therapeutics

    See if you can join NCT07030257 on ClinicalTrials.gov

11. Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

    The goal of this study is to better understand how to best treat participants with advanced bladder cancer who may not be able to tolerate all of the chemotherapy drugs that have been shown to be effective. In this study, investigators are assessing the role of the survey, the Geriatric-8, and its …

    Stage

    Not phased

    Ages

    65 and older

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT06138561 on ClinicalTrials.gov

12. Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

    Subjects will be randomized into 2 groups (stent or no stent) prior to radical cystectomy with ileal conduit urinary diversion (RCIC). They will follow the standard of care and be enrolled in the study for 12 months post-op. Risk of post-op complications will be analyzed.

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

    Locations

    2 in total

    Run by

    Thomas Jefferson University

    See if you can join NCT07234968 on ClinicalTrials.gov

13. A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

    Phase 1 dose escalation and expansion study of CLSP-1025, a first-in-class HLA-A*02:01 specific T cell engager (TCE) targeting solid tumors that harbor the p53 R175H mutation.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    HonorHealth Research Institute, Scottsdale, Arizona

    Locations

    21 in total

    Run by

    Clasp Therapeutics, Inc.

    See if you can join NCT06778863 on ClinicalTrials.gov

14. CONFIRM: Magnetic Resonance Guided Radiation Therapy

    This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham & Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT04368702 on ClinicalTrials.gov

15. Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

    This study is a first in human Phase 1 study that involves patients with a type of cancer called HER2 (Human Epidermal Growth Factor Receptor 2) positive cancer. This study asks patients to volunteer to take part in a research study investigating the safety and efficacy of using special immune cell…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Baylor St. Luke's Medical Center, Houston, Texas

    Run by

    Baylor College of Medicine

    See if you can join NCT03740256 on ClinicalTrials.gov

16. Improving Care for Rural Patients With Solid Tumors

    This study will assess if the CARES (Cancer Advocacy, Resources, Education and Support) intervention improves time to start of treatment after diagnosis and time to treatment completion for solid tumors (ex: lung, head, neck, thyroid, cervical, breast, bladder, colon, and rectal cancers) in rural p…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of Colorado Hospital, Aurora, Colorado

    Locations

    14 in total

    Run by

    University of Colorado, Denver

    See if you can join NCT04916990 on ClinicalTrials.gov

17. A Novel Multiplex ELISA Assay for Surveilling Patients With History of Bladder Cancer

    Voided urinary cytology (VUC) is the most widely used urine-based assay for detecting bladder cancer (BCa); however, it fails to detect approximately 50% of low-grade or early stage BCa when it is most curable. Furthermore, the detection rate of VUC for recurrent BCa is not much better. Because of …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cedars-Sinai Medical Center, Los Angeles, California

    Locations

    4 in total

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT03193515 on ClinicalTrials.gov

18. A Novel Multiplex ELISA Assay for Evaluating Patients With Microscopic Hematuria for Bladder Cancer

    To improve upon the non-invasive detection of BCa by further validating a multiplex ELISA assay directed at a BCa-associated diagnostic signature in voided urine samples of patients with microscopic hematuria.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    VA Long Beach Healthcare System, Long Beach, California

    Locations

    8 in total

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT03193541 on ClinicalTrials.gov

19. cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

    This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gast…

    Stage

    Not phased

    Ages

    40 and older

    Site

    City of Hope, Duarte, California

    Locations

    17 in total

    Run by

    Adela, Inc

    See if you can join NCT05366881 on ClinicalTrials.gov

20. Renal Retention in High Grade Upper Tract Urothelial Cancer

    This trial will evaluate the use of combination pembrolizumab and enfortumab vedotin for patients with high grade non-metastatic (cN0/NxMx, no measurable regional lymph nodes, no metastases) upper tract urothelial cancer (UTUC), preferring to forego standard of care radical nephroureterectomy (RNU)…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Johns Hopkins University: Sibley Memorial Hospital, Washington D.C., District of Columbia

    Locations

    2 in total

    Run by

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    See if you can join NCT05656235 on ClinicalTrials.gov

21. A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

    A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expansion (RDE) of intratumoral ONM-501 as monotherapy and in combination with a PD-1 checkpoint inhibit…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    St Vincent's Hospital, Darlinghurst, New South Wales

    Locations

    16 in total

    Run by

    OncoNano Medicine, Inc.

    See if you can join NCT06022029 on ClinicalTrials.gov

22. Blue Light Cystoscopy With Cysview® Registry

    Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Alabama at Birmingham, Birmingham, Alabama

    Locations

    23 in total

    Run by

    Photocure

    See if you can join NCT02660645 on ClinicalTrials.gov

23. Image-Guided Gynecologic Brachytherapy

    This research is being done to evaluate multimodality imaging, including magnetic resonance imaging-guided therapy (MRT), as a possible treatment for gynecologic cancers. The therapy takes place in the Department of Radiation Oncology at the Johns Hopkins SKCCC. The purpose of this study is to inve…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    The SKCCC at Johns Hopkins, Baltimore, Maryland

    Run by

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    See if you can join NCT02993900 on ClinicalTrials.gov

24. Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

    This is a single arm, interventional pilot study of using chlorhexidine irrigation intra-operatively and post-operatively among patients undergoing radical cystectomy with urinary diversion. The intervention comprises of using irrigation of ileal conduit or ileal neobladder intra-operatively and th…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mount Sinai Hospital, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT06689176 on ClinicalTrials.gov

25. Home Intravenous Fluid Infusion After Undergoing Radical Cystectomy

    Radical cystectomy is the standard of care for muscle invasive bladder cancer, however despite advances, it is still associated with high morbidity. Many complications may be driven by dehydration and it is unclear if a home intravenous fluid (IVF) infusion program post-operatively, which is an acc…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Johns Hopkins Hospital, Baltimore, Maryland

    Locations

    2 in total

    Run by

    Johns Hopkins University

    See if you can join NCT07225205 on ClinicalTrials.gov