Bladder Cancer Clinical Trials

85 studies are recruiting for bladder cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)

   The goal of this clinical trial is to learn if gemcitabine/cisplatin plus cemiplimab with or without fianlimab works to treat bladder cancer in adults. The main question it aims to answer is: Can gemcitabine, cisplatin, and cemiplimab with or without fianlimab treat bladder cancer? Participants wil…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York, New York

   Run by

   Columbia University

   See if you can join NCT06571708 on ClinicalTrials.gov

2. Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

   The purpose of this study is to examine the usefulness of implanting small 24-K gold fiducial markers around a bladder tumor site, so that a Radiation Oncologist can identify the original tumor location at the time of radiation treatment. Other goals of the study include assessing whether a new MRI…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center (CSMC), Los Angeles, California

   Locations

   3 in total

   Run by

   Cedars-Sinai Medical Center

   See if you can join NCT04442724 on ClinicalTrials.gov

3. A Beta-only IL-2 ImmunoTherapY Study

   This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Sharp Memorial Hospital, San Diego, California

   Locations

   27 in total

   Run by

   Medicenna Therapeutics, Inc.

   See if you can join NCT05086692 on ClinicalTrials.gov

4. Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer

   This is a phase II, single arm, Simon two-stage design, trial, enrolling patients with cisplatin ineligible MIBC and/or those patients who decline cisplatin based NAC. Assess rates of pathologic downstaging and quality of life in MIBC cisplatin-ineligible/declined patients when IVC is added to gemc…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   The University of Kansas Cancer Center, Kansas City, Kansas

   Locations

   2 in total

   Run by

   University of Kansas Medical Center

   See if you can join NCT06493370 on ClinicalTrials.gov

5. Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

   The goal of this clinical trial is to demonstrate the feasibility of bladder transplantation in patients with terminal bladder diseases who would benefit from a new bladder or a combined kidney and bladder transplant. The main questions it aims to answer are: * Is human bladder transplantation feas…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   UCLA, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT06337942 on ClinicalTrials.gov

6. Pre-Habilitation with Mindfulness and Exercise for Patients Undergoing Radical Cystectomy (PRIMER Trial)

   The PRIMER (Pre-Habilitation With Mindfulness and Exercise for Patients Undergoing Radical Cystectomy) trial is a pilot designed to estimate the feasibility of integrating a home-based pre-operative exercise and mindfulness program (pre-habilitation program) for patients scheduled to undergo radica…

   Stage

   Not phased

   Ages

   18 to 90

   Site

   University of Virginia, Charlottesville, Virginia

   Run by

   University of Virginia

   See if you can join NCT05790850 on ClinicalTrials.gov

7. LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors

   Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent m…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT04979156 on ClinicalTrials.gov

8. A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

   This research study is a pilot clinical trial, which hypothesizes that the combination of electromagnetic tracking in conjunction with laparoscope imaging and ultrasound probe imaging will aid in reducing the complexity of both laparoscopic lymphadenectomy and/or organ removal in patients with a co…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT05899361 on ClinicalTrials.gov

9. Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol

   To determine if Alvimopan during open or robotic radical cystectomy with urinary diversion results in quicker return of bowel function (GI-2 recovery = time to upper [first toleration of solid food] and lower [first bowel movement] gastrointestinal recovery) compared to placebo.

   Stage

   Phase 3

   Ages

   18 to 85

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT03216525 on ClinicalTrials.gov

10. Patient-Centered Surgical Prehabilitation

    The purpose of this research is to validate the prehabilitation program which is defined as a set of interventions meant to prepare the body physically and nutritionally for the cystectomy procedure.

    Stage

    Not phased

    Ages

    18 to 85

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT05715684 on ClinicalTrials.gov