Autism Spectrum Disorder Clinical Trials

104 studies are recruiting for autism spectrum disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. How Simplified Language Affects Comprehension and Learning in Young Autistic Children

   The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD. The overall objective is to determine how single-word and telegraphic simplification affects real-time language processing and word lear…

   Stage

   Not phased

   Ages

   1 to 4

   Site

   Michigan State University, East Lansing, Michigan

   Run by

   Michigan State University

   See if you can join NCT05707923 on ClinicalTrials.gov

2. Early Diagnostic Response Model (EDRM)

   Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this study is to develop, pilot, and evaluate a diagnostic protocol for childr…

   Stage

   Not phased

   Ages

   1 to 3

   Site

   Emory Autism Center, Atlanta, Georgia

   Run by

   Emory University

   See if you can join NCT05419895 on ClinicalTrials.gov

3. Retrieval-Based Word Learning in Autistic Children

   Children on the autism spectrum sometimes have difficulty learning new words and using the newly taught information in different situations. In this study, the investigators are testing whether strategies that have been found to improve word learning in non-autistic children will also help autistic…

   Stage

   Not phased

   Ages

   4 to 10

   Site

   Louisiana State University, Baton Rouge, Louisiana

   Run by

   Louisiana State University and A&M College

   See if you can join NCT06466876 on ClinicalTrials.gov

4. Cerebellar tDCS in Children With Autism Spectrum Disorder

   The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to examine its effects on some of the symptoms of ASD, such as repetitive beha…

   Stage

   Not phased

   Ages

   4 to 17

   Site

   Children's Medical Center, Dallas, Texas

   Locations

   2 in total

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT04446442 on ClinicalTrials.gov

5. GAIP ASD Research Study

   This clinical research study evaluates the safety and preliminary effects of AdiaVita (umbilical cord blood-derived stem cells and exosomes) combined with glutathione versus glutathione alone in people aged 3 and older with Autism Spectrum Disorder (ASD). In this randomized, participant-blinded cro…

   Stage

   Phase 1

   Ages

   3 and older

   Site

   Greater Atlanta Integrative Pediatrics, Roswell, Georgia

   Locations

   2 in total

   Run by

   Greater Atlanta Integrative Pediatrics

   See if you can join NCT07622316 on ClinicalTrials.gov

6. FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

   FOXP1, also known as Forkhead-box Protein P1, is a transcription factor protein belonging to the FOX gene family. Disruptions in the FOXP1 gene cause a phenotype characterized by global developmental delay, speech deficits, mild dysmorphic features, and traits of autism spectrum disorder. This stud…

   Stage

   Not phased

   Ages

   2 and older

   Site

   The Seaver Autism Center for Research and Treatment, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT03718923 on ClinicalTrials.gov

7. Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

   The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and s…

   Stage

   Not phased

   Ages

   1 to 3

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT05880225 on ClinicalTrials.gov

8. Emergent Multi-Class Imitation Training

   The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate generalized imitation called Emergent Multi-Class Imitation Training (…

   Stage

   Not phased

   Ages

   1 to 6

   Site

   Rutgers University, New Brunswick, New Jersey

   Run by

   Rutgers, The State University of New Jersey

   See if you can join NCT05849376 on ClinicalTrials.gov

9. Online Pivotal Response Treatment Training in Autism Spectrum Disorder

   This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD). The study will specifically investigate whether participants can learn to deliver PRT effectively following part…

   Stage

   Not phased

   Ages

   2 to 5

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT06523387 on ClinicalTrials.gov

10. Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose

    The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings…

    Stage

    Phase 2

    Ages

    3 to 12

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT04278898 on ClinicalTrials.gov

11. Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial

    The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings…

    Stage

    Phase 2

    Ages

    3 to 12

    Site

    Department of Psychiatry and Behavioral Sciences, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT05664789 on ClinicalTrials.gov

12. Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism

    This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11. BlinkLab Dx1 is a non-invasive, smartphone-based application under development as a diagnostic …

    Stage

    Not phased

    Ages

    2 to 11

    Site

    Remote study conducted nationwide; all participation occurs via smartphone app at home., Princeton, New Jersey

    Run by

    Blinklab Limited

    See if you can join NCT07590973 on ClinicalTrials.gov

13. TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

    Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure. Autistic people identify approaches to effectively addressing trauma as a top mental health research priority, yet provid…

    Stage

    Not phased

    Ages

    6 and older

    Site

    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT07420478 on ClinicalTrials.gov

14. Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism

    The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves social communication as well as the core and associated symptoms of ASD. The investigators wil…

    Stage

    Phase 2

    Ages

    2 to 5

    Site

    State University of New York, Downstate, Brooklyn, New York

    Locations

    2 in total

    Run by

    Southwest Autism Research & Resource Center

    See if you can join NCT04060030 on ClinicalTrials.gov

15. International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder

    To determine sufficient number of biological and clinical markers to identify subgroups of potential best responders to a specific medication

    Stage

    Not phased

    Ages

    12 to 65

    Site

    SARRC, Phoenix, Arizona

    Locations

    21 in total

    Run by

    Stalicla SA

    See if you can join NCT05590715 on ClinicalTrials.gov

16. A Digital Health Parent-Training Intervention for Children With Social Communication Delays

    Early intervention, during a time of optimal brain plasticity, is critical for autistic children to develop functional skills such as communication and daily living abilities. However, many families face barriers to accessing timely autism-specific services due to delays in autism diagnosis (which …

    Stage

    Not phased

    Ages

    1 and older

    Site

    Florida International University, Miami, Florida

    Run by

    Florida International University

    See if you can join NCT07551752 on ClinicalTrials.gov

17. Piloting the Competence in Romance and Understanding Sexual Health Curriculum

    The goal of this clinical trial is to learn whether the CRUSH curriculum is possible (feasible), whether it fits the needs of the adults it is designed for (acceptable), and shows initial signs of being helpful (efficacious). CRUSH is a group-based behavioral intervention plus 1-1 coaching designed…

    Stage

    Not phased

    Ages

    18 to 30

    Site

    Boston Children's Hospital, Two Brookline Place, Brookline, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT07406100 on ClinicalTrials.gov

18. Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

    The study involves up to 5 visits for a fasting blood draw, behavioral assessments, and/or questionnaires. Other samples may be collected when appropriate. This study is currently recruiting. There is no cost for visits or study-related exams.

    Stage

    Not phased

    Ages

    Up to 18

    Site

    Southwestern Research and Resource Center, Phoenix, Arizona

    Locations

    2 in total

    Run by

    Southwest Autism Research & Resource Center

    See if you can join NCT04322734 on ClinicalTrials.gov

19. DINO RCT - Treating Anxiety in Children With Autism

    Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive and language delays. Anxiety treatment models utilizing cognitive-behav…

    Stage

    Not phased

    Ages

    4 to 6

    Site

    Kennedy Krieger Institute, Baltimore, Maryland

    Run by

    Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

    See if you can join NCT06066983 on ClinicalTrials.gov

20. Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services

    This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings. Study aims are to test the clinical and implementation effectiveness of training mental he…

    Stage

    Not phased

    Ages

    6 to 99

    Site

    San Diego State University, San Diego, California

    Locations

    2 in total

    Run by

    San Diego State University

    See if you can join NCT06651086 on ClinicalTrials.gov

21. Patterns of Neurodevelopmental Disorders

    The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.

    Stage

    Not phased

    Ages

    Any age

    Site

    Rossignol Medical Center, Phoenix, Arizona

    Run by

    Richard Frye

    See if you can join NCT06213090 on ClinicalTrials.gov

22. TB006 for Autism Spectrum Disorder

    Multisite 14-week prospective double-blind placebo controlled parallel-group randomized clinical trial with 14-week open-label extension at the end of double-blind treatment phase for placebo subjects. Eligible subjects will be randomized within each site in 2:1 ratio to receive either TB006 or pla…

    Stage

    Phase 2

    Ages

    18 to 35

    Site

    Rossignol Medical Center, Phoenix, Arizona

    Locations

    2 in total

    Run by

    Rossignol Medical Center

    See if you can join NCT06500637 on ClinicalTrials.gov

23. Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults

    Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and limited workforce capacity. It has been argued that improving impairment …

    Stage

    Not phased

    Ages

    10 to 30

    Site

    University of Alabama, Tuscaloosa, Alabama

    Locations

    2 in total

    Run by

    University of Pittsburgh

    See if you can join NCT06158581 on ClinicalTrials.gov

24. Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

    Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric acid (GABA). They want to learn how abnormalities in the GABA system may contribute to ASD. Objective: To see if repetitive transcranial m…

    Stage

    Not phased

    Ages

    11 to 25

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Institute of Mental Health (NIMH)

    See if you can join NCT04798274 on ClinicalTrials.gov

25. Improving Barriers to Care Access for Children With Autism and Related Needs Via Telehealth for Evaluation, Care Navigating, and Caregiver Coaching

    The objectives of the current project are to develop and implement training with community providers to evaluate a supplemental parent coaching intervention delivered via telehealth to improve child communication and behavioral outcomes, parental stress outcomes, and to investigate telehealth model…

    Stage

    Not phased

    Ages

    1 and older

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT07520838 on ClinicalTrials.gov