Autism Spectrum Disorder Clinical Trials

103 studies are recruiting for autism spectrum disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project

   The purpose of this research study is to investigate the effects of transcranial direct current stimulation (tDCS) on some of the challenges faced by children with Autism Spectrum Disorder (ASD).

   Stage

   Not phased

   Ages

   5 to 21

   Site

   UT Southwestern Medical Center, Dalls, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT05691283 on ClinicalTrials.gov

2. Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare

   Autism spectrum disorder (ASD) is a developmental condition that can affect communication, social interaction, and behavior. Identifying ASD early helps children and families access support services sooner. Pupillometry is a way of measuring the nervous system and brain function by recording the pu…

   Stage

   Not phased

   Ages

   2 to 5

   Site

   SEL Health Clinic - Lewiston, Lewiston, Idaho

   Locations

   4 in total

   Run by

   Schweitzer Engineering Laboratories

   See if you can join NCT07903675 on ClinicalTrials.gov

3. COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD

   Purpose: The purpose of this project is to develop and test the COMPASS [Collaborative Model for Competence and Success] Across Settings (CAST) intervention to enhance the goal setting and attainment skills of autistic youth. Despite federal education law mandating transition services as part of th…

   Stage

   Not phased

   Ages

   16 to 99

   Site

   Ball State University, Muncie, Indiana

   Run by

   Ball State University

   See if you can join NCT06309160 on ClinicalTrials.gov

4. Word Learning From Parentese in Autistic Children

   The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

   Stage

   Not phased

   Ages

   1 to 4

   Site

   University of Texas at Dallas, Richardson, Texas

   Run by

   The University of Texas at Dallas

   See if you can join NCT06649916 on ClinicalTrials.gov

5. AWARE: Management of ADHD in Autism Spectrum Disorder

   This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism. Using a sequential, multiple assignment randomization trial (SMART) design the study will…

   Stage

   Phase 4

   Ages

   4 to 17

   Site

   University of California, Irvine, Irvine, California

   Locations

   13 in total

   Run by

   Daniel Coury

   See if you can join NCT05916339 on ClinicalTrials.gov

6. Improving Academic and Social Functioning in Middle-Schoolers With Autism

   The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD). One of the interventions focuses on teaching parents and adolescent skills to help improve their social functioning and the other focuses on teaching parents and a…

   Stage

   Not phased

   Ages

   10 to 15

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT06705907 on ClinicalTrials.gov

7. Heart Rate Variability Biofeedback for Anxiety in Autistic Youth

   Heart rate variability biofeedback (HRVB) is a breathing-based intervention that reduces anxiety in a range of populations. Second-generation wearable HRVB devices not only deliver scheduled biofeedback practice sessions but also allow patients to practice HRVB in-the-moment when it is needed most.…

   Stage

   Phase 2

   Ages

   12 to 17

   Site

   Lurie Center, Lexington, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07812233 on ClinicalTrials.gov

8. FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

   FOXP1, also known as Forkhead-box Protein P1, is a transcription factor protein belonging to the FOX gene family. Disruptions in the FOXP1 gene cause a phenotype characterized by global developmental delay, speech deficits, mild dysmorphic features, and traits of autism spectrum disorder. This stud…

   Stage

   Not phased

   Ages

   2 and older

   Site

   The Seaver Autism Center for Research and Treatment, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT03718923 on ClinicalTrials.gov

9. Developing Brain, Impulsivity and Compulsivity

   Background: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders. Researchers want to study changes in the brain to learn more about these behaviors…

   Stage

   Not phased

   Ages

   6 to 80

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT04631042 on ClinicalTrials.gov

10. Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

    This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia, bipolar disorder or autism spectrum disorder.

    Stage

    Phase 3

    Ages

    5 to 17

    Site

    Southwest Autism Research and Resource Center, Phoenix, Arizona

    Locations

    65 in total

    Run by

    Intra-Cellular Therapies, Inc.

    See if you can join NCT06229210 on ClinicalTrials.gov

11. Adia Med of Winter Park LLC Autism Spectrum Disorder Research Study

    This 12-month study tests whether AdiaVita (umbilical cord blood-derived stem cells and exosomes) plus glutathione improves autism symptoms more than glutathione alone in children ages 3-12. About 100 children with confirmed autism will be randomly assigned to one of two groups. One group receives …

    Stage

    Phase 1

    Ages

    3 to 12

    Site

    Adia Med Of Winter Park, Winter Park, Florida

    Locations

    2 in total

    Run by

    Adia Med of Winter Park LLC

    See if you can join NCT07304440 on ClinicalTrials.gov

12. Buspirone for Anxiety in Autistic Youth

    The purpose of the study is to do a preliminary trial to determine if buspirone is effective, safe, and tolerable in autistic youth with anxiety.

    Stage

    Phase 4

    Ages

    7 to 17

    Site

    Lurie Center, Lexington, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07439042 on ClinicalTrials.gov

13. Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

    Background: Creatine transporter deficiency (CTD) is a genetic disorder that mainly affects the brain in males. CTD causes intellectual disability that can be mild to severe. People with CTD may have seizures and behavioral issues. They may have slow growth and tire easily. CTD may sometimes be con…

    Stage

    Not phased

    Ages

    2 to 40

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    See if you can join NCT05600946 on ClinicalTrials.gov

14. Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)

    The purpose of this clinical trial is to investigate the effects of multiple sessions of transcranial direct current stimulation (tDCS) delivered while participants complete tasks that target social learning with high functioning adults with ASD and/or high traits of ASD. The main question it aims …

    Stage

    Not phased

    Ages

    18 to 35

    Site

    University of New Mexico, Albuquerque, New Mexico

    Run by

    University of New Mexico

    See if you can join NCT06495684 on ClinicalTrials.gov

15. Family-school Partnership Intervention for Early Childhood Education

    Strategies for creating and maintaining reciprocal partnerships between teachers and parents are considered essential elements of developmentally appropriate practice in early childhood education (ECE). Particularly for children who are high-risk for behavioral, developmental, or mental health prob…

    Stage

    Not phased

    Ages

    2 to 6

    Site

    UNT, Denton, Texas

    Run by

    University of North Texas, Denton, TX

    See if you can join NCT06506097 on ClinicalTrials.gov

16. Pimavanserin for Rigid-compulsive Symptoms in Autism Spectrum Disorder

    This Phase 2 study examines the safety, tolerability, and preliminary efficacy of pimavanserin in individuals with Autism Spectrum Disorder. Male or female participants aged 12 to 40 years of age will be randomized to receive single doses of either placebo or pimavanserin in this randomized, placeb…

    Stage

    Phase 2

    Ages

    12 to 40

    Site

    University of Kansas, Center for Research, Lawrence, Kansas

    Locations

    2 in total

    Run by

    New York State Psychiatric Institute

    See if you can join NCT05999240 on ClinicalTrials.gov

17. A Phase 2A Trial of DT402 for Autism Spectrum Disorder

    A Phase 2A Trial of DT402 Open-Label Study in Adults with Autism Spectrum Disorder

    Stage

    Phase 2

    Ages

    18 to 65

    Site

    Spectrum Neuroscience and Treatment Institute, New York, New York

    Run by

    Definium Therapeutics US, Inc.

    See if you can join NCT07303907 on ClinicalTrials.gov

18. Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

    The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors. Participants will be randomly assigned to receive either propranolol or a placebo (a look-al…

    Stage

    Phase 2

    Ages

    12 to 40

    Site

    New York State Institute for Basic Research (IBR), Staten Island, New York

    Locations

    2 in total

    Run by

    Jeremy Veenstra-vanderweele

    See if you can join NCT07091279 on ClinicalTrials.gov

19. Smart Inhaler and Remote Asthma Management in Adolescents With Intellectual and Developmental Disabilities

    Correct use of daily medications containing inhaled corticosteroids is key for asthma control, yet children with intellectual and developmental disabilities (IDD) face additional barriers to proper inhaler use. Smart inhalers, a novel technology that provides guidance and immediate feedback on inha…

    Stage

    Not phased

    Ages

    10 to 17

    Site

    Children's Hospital Los Angeles, Los Angeles, California

    Run by

    Children's Hospital Los Angeles

    See if you can join NCT07746921 on ClinicalTrials.gov

20. Evaluation and Refinement of KF-STRIDE Into the Interview!

    Examine the acceptability, usability, feasibility, and initial efficacy of KF-STRIDE 3.0, the data from which will serve as a basis for a future fully powered RCT

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Kessler Foundation, East Hanover, New Jersey

    Run by

    Kessler Foundation

    See if you can join NCT07168941 on ClinicalTrials.gov

21. Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder

    The goal of this clinical trial is to learn how prednisone affects adults with autism spectrum disorder (ASD). It will also learn about the safety of prednisone. The main questions it aims to answer are: * How does prednisone affect the core features and associated target symptoms of ASD in adults …

    Stage

    EARLY_Phase 1

    Ages

    18 to 50

    Site

    MGH Lurie Center for Autism, Lexington, Massachusetts

    Run by

    Christopher John McDougle, M.D.

    See if you can join NCT06934915 on ClinicalTrials.gov

22. Improving Social Communication in Individuals With ASD Using AI

    The purpose of this study is to identify whether researched and commonly used face-to-face interventions can be effectively implemented through artificial intelligence (AI) using an application on the phone or computer. The investigators plan to recruit individuals diagnosed with autism spectrum di…

    Stage

    Not phased

    Ages

    3 to 35

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT05987774 on ClinicalTrials.gov

23. Auricular Transcutaneous Electrical Nerve Stimulation Treatment of Autism

    In this study, investigators will examine the treatment effects of transcutaneous electrical nerve stimulation with different stimulation frequencies on individuals with autism.

    Stage

    Not phased

    Ages

    18 to 60

    Site

    MGB, Charlestown, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT03827941 on ClinicalTrials.gov

24. Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder

    This study will assess clinical and behavioral measures along with electroencephalogram (EEG), event-related potentials (ERPS), and eye-tracking (ET) prior to and following a single intermittent Theta Burst Stimulation (iTBS) session to provide preliminary insight into the potential of TMS as an in…

    Stage

    Not phased

    Ages

    18 to 40

    Site

    Yale Psychiatric Hospital, New Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT06142955 on ClinicalTrials.gov

25. Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients

    The purpose of this study is to evaluate the effectiveness of the behavior analytic intervention in reducing the number of challenging behaviors exhibited by patients with Autism Spectrum Disorder (ASD) while increasing compliance with needle-related simulations and procedures. A second purpose is …

    Stage

    Not phased

    Ages

    3 and older

    Site

    Boston Medical Center, Boston, Massachusetts

    Run by

    Boston Medical Center

    See if you can join NCT06712784 on ClinicalTrials.gov