Vascular Diseases Clinical Trials in Boston, Massachusetts

5 studies are recruiting for vascular diseases in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

   The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy informed by coronary CT angiography (CCTA) will improve procedural efficiency and effectiveness compared with the current standard of care (IVUS-…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Bringham and Women's Hospital, Boston, Massachusetts

   Locations

   14 in total

   Run by

   Fundación EPIC

   See if you can join NCT07286578 on ClinicalTrials.gov

2. A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

   This is a Phase 2, open-label, multi-center clinical study to evaluate the safety and tolerability of inhaled mosliciguat in participants with pulmonary hypertension associated with interstitial lung disease (PH-ILD) on a background inhaled treprostinil.

   Stage

   Phase 2

   Ages

   18 to 85

   Site

   Clinical Research Site, Boston, Massachusetts

   Locations

   13 in total

   Run by

   Pulmovant, Inc.

   See if you can join NCT07333183 on ClinicalTrials.gov

3. Global Paradise System US Post Approval Study

   The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   43 in total

   Run by

   ReCor Medical, Inc.

   See if you can join NCT06297291 on ClinicalTrials.gov

4. SPYRAL GEMINI Pilot Study

   The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Locations

   18 in total

   Run by

   Medtronic Vascular

   See if you can join NCT06907147 on ClinicalTrials.gov

5. Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

   This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypertension. This research will be conducted using de-identified electronic health records (EHR) and administrative health insurance claims data.…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Medtronic Vascular

   See if you can join NCT07174622 on ClinicalTrials.gov