Type 2 Diabetes Clinical Trials

101 studies are recruiting for type 2 diabetes in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Type 2 Continuous Glucose Monitoring Academy

   The goal of this clinical trial is to evaluate the Impact of Continuous Glucose Monitoring Academy Education Curriculum Versus Standard Care on Glycemic Outcomes for Youth With Type 2 Diabetes (T2D): * The first aim is to determine how feasible it is to adapt the Continuous Glucose Monitoring Acade…

   Stage

   Not phased

   Ages

   8 to 21

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT06516640 on ClinicalTrials.gov

2. Ultrasound Effects on Glycemic Control in T2DM

   This is an open label, exploratory pilot study that will assess the effects of dual site focused pulsed ultrasound treatment on glycemic parameters in subjects with T2DM.

   Stage

   Not phased

   Ages

   21 to 75

   Site

   Yale-New Haven Hospital, New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT05354947 on ClinicalTrials.gov

3. Extracellular Vesicles, Insulin Action, and Exercise

   Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people. The purpose of this study is to understand how EVs play a role in type 2 diabetes…

   Stage

   Not phased

   Ages

   30 to 80

   Site

   Institute for Food, Nutrition, and Health, New Brunswick, New Jersey

   Locations

   3 in total

   Run by

   Rutgers, The State University of New Jersey

   See if you can join NCT06546085 on ClinicalTrials.gov

4. Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

   This study will provide insight into whether cardiac function changes with oral Ketone Esters (KE) administered to patients with Type 2 Diabetes Mellitus (T2DM) and Heart failure with reduced ejection fraction (HFrEF). Plasma ketones are avidly extracted by cardiac muscle and their uptake is not de…

   Stage

   EARLY_Phase 1

   Ages

   18 to 80

   Site

   University of Texas Health Science Center at San Antonio, San Antonio, Texas

   Run by

   The University of Texas Health Science Center at San Antonio

   See if you can join NCT06108076 on ClinicalTrials.gov

5. Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

   Objectives: This study aims to test whether a mobile app called PortionSize Ed can help adults who have had a recent stroke and also have prediabetes or type 2 diabetes improve their diet. Specifically, we want to see if the app can help people follow a Mediterranean-style diet, which may lower the…

   Stage

   Not phased

   Ages

   30 to 65

   Site

   University of Hawaii Cancer Center, Honolulu, Hawaii

   Run by

   University of Hawaii

   See if you can join NCT07120334 on ClinicalTrials.gov

6. Precision Dosing of Metformin in Youth With T2D

   The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).

   Stage

   EARLY_Phase 1

   Ages

   10 to 21

   Site

   UCSF Benioff Children's Hospital Oakland, Pediatric Diabetes Clinic, Oakland, California

   Locations

   2 in total

   Run by

   University of California, San Francisco

   See if you can join NCT06120881 on ClinicalTrials.gov

7. High Fructose Diet, the Gut Microbiome, and Metabolic Health

   Americans commonly consume excess amounts of dietary fructose. Added fructose has been shown to have an adverse impact on metabolic health, including increased insulin resistance and type 2 diabetes (T2D) risk. However, the mechanisms that link dietary fructose and metabolic health are poorly under…

   Stage

   Not phased

   Ages

   25 to 45

   Site

   Mount Sinai Morningside, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT06329544 on ClinicalTrials.gov

8. A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients

   The purpose of this project is to test the effect of a low carb diet compared to standard carb diet among adolescents with T2D over a 24-week period.

   Stage

   Not phased

   Ages

   12 to 18

   Site

   University of Alabama at Birmingham/ Children's of Alabama, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06902077 on ClinicalTrials.gov

9. Continuous Glucose Monitors (CGMs) for All: Studying the Impact of Expanding CGM Access

   This non-blinded, non-randomized pre-post study will examine the impact of providing CGM sensors free of charge to adult patients of Fair Haven Community Health Care with poorly controlled type 2 diabetes on glycemic control and quality of life.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Fair Haven Community Health Care (FHCHC), New Haven, Connecticut

   Run by

   Yale University

   See if you can join NCT06658067 on ClinicalTrials.gov

10. More Fresh Fruit and Vegetable Prescription Program for Families With Type 2 Diabetes Mellitus

    Rady Children's Hospital San Diego (RCHSD), UCSD Division of Child and Community Health and the Center for Community Health, and Northgate Gonzalez (NG) Markets will collaborate to create a Produce Prescription Program (Fruit and Vegetable Prescription Program) to be implemented in the RCHSD Diabet…

    Stage

    Not phased

    Ages

    Up to 18

    Site

    Rady Children's Hospital San Diego, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT05138432 on ClinicalTrials.gov

11. Gut Microbiota in Metabolic Surgery

    Metabolic surgery is an emerging option to treat obesity-related metabolic diseases (e.g., type 2 diabetes) and prevent cardiovascular disease (CVD). Metabolic surgery can profoundly alter the gut microbiota; meanwhile, gut microbiota may affect surgical outcomes. Longitudinal studies that examined…

    Stage

    Not phased

    Ages

    21 to 65

    Site

    Vanderbilt_University MC, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05000996 on ClinicalTrials.gov

12. Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

    The goal of this clinical trial is to examine the role of autophagy on microvascular function in adults with Type 2 Diabetes. The main question it aims to answer are: * Does presence of Type 2 Diabetes reduce autophagy and impair microvascular function? * Does exposure to high glucose impair autoph…

    Stage

    EARLY_Phase 1

    Ages

    18 to 80

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT05593549 on ClinicalTrials.gov

13. Implementation of Team Clinic for Type 2 Diabetes (TCT2)

    The goal of this clinical trial is to learn if shared medical appointment is an acceptable way to deliver care to youth with type 2 diabetes. The main question[s] it aims to answer are: * Is shared medical appointments an acceptable care delivery model for this population? * Does shared medical app…

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Children's Hospital Los Angeles, Los Angeles, California

    Locations

    2 in total

    Run by

    Children's Hospital Los Angeles

    See if you can join NCT06923046 on ClinicalTrials.gov

14. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

    Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06055036 on ClinicalTrials.gov

15. Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes

    This study will test the preliminary efficacy of a joint patient/informal caregiver telephone-delivered intervention that includes diabetes education; problem solving around social needs; and behavioral activation for older African Americans with poorly controlled type 2 diabetes by randomizing 100…

    Stage

    Not phased

    Ages

    50 to 120

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT06279637 on ClinicalTrials.gov

16. Effectiveness of the Diabetes Homeless Medication Support (D-HOMES) Program on Diabetes Management

    The goal of this clinical trial is to learn if the Diabetes Homelessness Medication Support (D-HOMES) wellness coaching model is effective for adults who speak English or Spanish, have Type 2 diabetes with an HbA1c at or above 7.5, and have recently experienced homelessness. Researchers will compar…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Hennepin Healthcare Research Institute, Minneapolis, Minnesota

    Run by

    Katherine Vickery

    See if you can join NCT07091487 on ClinicalTrials.gov

17. Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

    This study has 3 aims. Aim 1: Identify social determinants of cardiometabolic health and determine facilitators and modifiable barriers in achieving treatment goals. Aim 2: Assess PLWH knowledge, skills, and confidence for self-management of cardiometabolic disorders. Aim 3: Tailor a self-managemen…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Duke University - Charlotte Study Sites, Charlotte, North Carolina

    Locations

    2 in total

    Run by

    Duke University

    See if you can join NCT05129345 on ClinicalTrials.gov

18. Enhancing Diabetes Care: Exposome &Amp; Sensors

    The study aims to integrate various data types, such as electronic health records, wearable device data, and environmental data, to create a comprehensive, personalized diabetes care model. The study will focus on people with type 2 diabetes living in specified vulnerable zip codes.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    University of Illinois - Chicago, Chicago, Illinois

    Locations

    2 in total

    Run by

    University of Illinois at Chicago

    See if you can join NCT06989008 on ClinicalTrials.gov

19. DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

    SGLT2 inhibitors have demonstrated to mitigate cardiorenal risk in people with type 2 diabetes and are likely to play an increasingly large role in the treatment of patients with diabetes, chronic kidney disease and hypertension. Yet the underlying mechanisms of its protective effects are incomplet…

    Stage

    Phase 4

    Ages

    18 to 85

    Site

    Childrens hospital colorado, Denver, Colorado

    Locations

    2 in total

    Run by

    Amsterdam UMC, location VUmc

    See if you can join NCT06983054 on ClinicalTrials.gov

20. ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community

    The purpose of this project is to examine the feasibility/acceptability of a one-day Acceptance and Commitment Therapy + Lifestyle Education group intervention paired with 12-weeks of Continuous Glucose Monitoring for patients with type 2 diabetes (T2D) living in rural communities. This study is be…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Sam Houston State University College of Osteopathic Medicine, Conroe, Texas

    Run by

    Sam Houston State University

    See if you can join NCT06028503 on ClinicalTrials.gov

21. The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults

    The goal of this study is to determine the impact of pre-diabetes and type 2 diabetes on muscle atrophy during a period of bed rest and recovery of muscle mass, strength, and physical function following bed rest.

    Stage

    Not phased

    Ages

    60 to 80

    Site

    Translational Research Institute for Metabolism and Diabetes, Orlando, Florida

    Run by

    AdventHealth Translational Research Institute

    See if you can join NCT03761446 on ClinicalTrials.gov

22. My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes

    The proposed research and training will allow Dr. Alana Biggers to obtain critical research skills and study a mindfulness meditation program designed to improve sleep and reduce stress in African-American adults with diabetes. If effective, this program may reduce the risk of cardiovascular diseas…

    Stage

    Not phased

    Ages

    21 to 75

    Site

    University of Illinois at Chicago, Chicago, Illinois

    Run by

    University of Illinois at Chicago

    See if you can join NCT05208164 on ClinicalTrials.gov

23. Mobile App Logging for Diabetes in Pregnancy

    To determine the effect of using a mobile app versus paper logs on compliance and percentage in range blood sugars in monitoring blood sugar in pregnant women with diabetes.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Augusta University, Augusta, Georgia

    Run by

    Carolyn Zahler-Miller

    See if you can join NCT06005987 on ClinicalTrials.gov

24. Latinos Understanding the Need for Adherence in Diabetes Using E-Health

    Latinos Understanding the Need for Adherence in Diabetes using Care Coordination, Integrated Medical and Behavioral Care and E-Health (LUNA-E) is a randomized controlled trial (RCT) that will test the effectiveness a patient-centered, team-based, primary care intervention with E-Health enhancements…

    Stage

    Not phased

    Ages

    18 and older

    Site

    South Bay Latino Research Center, Chula Vista, California

    Run by

    San Diego State University

    See if you can join NCT05570734 on ClinicalTrials.gov

25. Enhancing Preventative Health Behaviors Among Emergency Department Hyperglycemic Patients

    The goal of this clinical trial is to increase Type 2 Diabetes Mellitus knowledge and awareness among patients who present to the Emergency Department with hyperglycemia. The main questions it aims to answer are: * How do patients view their risk of developing type 2 diabetes based on their demogra…

    Stage

    Not phased

    Ages

    18 and older

    Site

    One Robert Wood Johnson Place, New Brunswick, New Jersey

    Locations

    2 in total

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT06663813 on ClinicalTrials.gov