Type 1 Diabetes Clinical Trials in Houston, Texas

4 studies are recruiting for type 1 diabetes in Houston, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

   This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from randomization in persons aged 9 to <21 with recent-onset stage 3 T1D.

   Stage

   Phase 1

   Ages

   9 to 20

   Site

   Baylor College of Medicine, Houston, Texas

   Locations

   10 in total

   Run by

   City of Hope Medical Center

   See if you can join NCT07061574 on ClinicalTrials.gov

2. SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

   This is a Phase 2b, investigator- and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D).

   Stage

   Phase 2

   Ages

   5 to 40

   Site

   Texas Children's Hospital - Clinical Care Center - Pediatric Renal Clinic, Houston, Texas

   Locations

   70 in total

   Run by

   SAb Biotherapeutics, Inc.

   See if you can join NCT07187531 on ClinicalTrials.gov

3. Registry for Stage 2 Type 1 Diabetes

   Stage 2 Type 1 Diabates (T1D) is an early stage of T1D characterized by dysglycemia but not yet leading to clinical symptoms. Progression of the disease to Stage 3 (clinical T1D), leads to overt hyperglycemia requiring eventually exogenous insulin. TZIELD® (teplizumab-mzwv) has been approved to del…

   Stage

   Not phased

   Ages

   Any age

   Site

   Texas Children's Hospital- Site Number : 8400002, Houston, Texas

   Locations

   37 in total

   Run by

   Sanofi

   See if you can join NCT06481904 on ClinicalTrials.gov

4. Immune Function and the Progression to T1D

   To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammato…

   Stage

   Not phased

   Ages

   0 to 100

   Site

   Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital, Houston, Texas

   Locations

   3 in total

   Run by

   University of Florida

   See if you can join NCT05899439 on ClinicalTrials.gov