Treatment Resistant Depression Clinical Trials in New York, New York

6 studies are recruiting for treatment resistant depression in New York, New York right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

   The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation (DBS) as an adjunctive treatment of non-psychotic unipolar Major Depressive Disorder (MDD) in adults.

   Stage

   Not phased

   Ages

   22 to 70

   Site

   Mount Sinai Hospital, New York, New York

   Locations

   25 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT06423430 on ClinicalTrials.gov

2. DBS for TRD With the Medtronic Percept PC

   Of the estimated 30 million Americans who suffer from Major Depressive Disorder, approximately 10% are considered treatment resistant. Deep brain stimulation (DBS) to a region of the brain called the subcallosal cingulate (SCC) is an emerging strategy for treatment resistant depression (TRD), which…

   Stage

   Not phased

   Ages

   25 to 70

   Site

   Icahn School of Medicine at Mount Sinai, Mount Sinai West, New York, New York

   Run by

   Helen Mayberg, MD

   See if you can join NCT05773755 on ClinicalTrials.gov

3. A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

   Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Icahn School of Medicine at Mount Sinai, New York, New York

   Locations

   101 in total

   Run by

   LivaNova

   See if you can join NCT03887715 on ClinicalTrials.gov

4. A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

   This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatment resistant Major Depressive disorder (TRD) and will characterize the onset and durability of ant…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   The Medical Research Network, LLC, New York, New York

   Locations

   48 in total

   Run by

   atai Therapeutics, Inc.

   See if you can join NCT06524830 on ClinicalTrials.gov

5. Maintenance rTMS for Depression (Maitr-De)

   Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising intervention for treatment-resistant depression (TRD), yet substantial uncertainties persist regarding its efficacy as a maintenance treatment. This prospective study seeks to investigate the efficacy of maintenance rTMS…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Weill Cornell Medicine, New York, New York

   Locations

   3 in total

   Run by

   University of California, San Diego

   See if you can join NCT06938841 on ClinicalTrials.gov

6. Biomarker-guided rTMS for Treatment Resistant Depression

   Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression. The investigators are continuing to learn how to optimize outcomes from rTMS treatment. The purpose of this research project is to use brain network connectivity patterns as measured by resting state functional magne…

   Stage

   Phase 3

   Ages

   22 to 65

   Site

   Weill Cornell Medicine, New York, New York

   Locations

   2 in total

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT04041479 on ClinicalTrials.gov