Tobacco Use Clinical Trials

31 studies are recruiting for tobacco use in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Abuse Liability for Five Modern Oral Nicotine Products

   This is a two-site, open-label, randomized, 4-way (2 arm) cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics [PD]) and plasma nicotine uptake (pharmacokinetics [PK]) during and following ad libitum use of …

   Stage

   Not phased

   Ages

   21 to 60

   Site

   Dr. Vince Clinical Research, Overland Park, Kansas

   Run by

   RAI Services Company

   See if you can join NCT07132814 on ClinicalTrials.gov

2. Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

   This study is investigating tobacco use and providing tobacco treatment among people experiencing homelessness in California, in San Francisco and Los Angeles.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07148232 on ClinicalTrials.gov

3. Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

   Individuals with chronic pain are more likely to smoke cigarettes and have more difficulty quitting smoking than the general population, in part because withdrawal from smoking can lead to temporary increases in pain. This research will examine how smoking withdrawal changes the way the brain proce…

   Stage

   Not phased

   Ages

   21 to 65

   Site

   Duke North Pavilion, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06983678 on ClinicalTrials.gov

4. Impact of Semaglutide on Tobacco Use and Related Health Behaviors

   This pilot randomized trial will assess the impact of 12 weeks of semaglutide administration (vs placebo) on changes in: (i) tobacco use and related factors (nicotine craving, withdrawal, motivation to quit, etc.) and (ii) biological biomarkers of health (e.g., epigenetics, glucose variability via …

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   Health Promotion Research Center, Oklahoma City, Oklahoma

   Run by

   University of Oklahoma

   See if you can join NCT06986993 on ClinicalTrials.gov

5. Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux

   The veteran population is at increased risk for EAC and its precursor lesion, Barrett's esophagus (BE), due to increased prevalence of disease risk factors compared to the general population. BE is traditionally diagnosed only when patients undergo endoscopy with biopsies. However, due to the high …

   Stage

   Not phased

   Ages

   40 to 85

   Site

   VA Northeast Ohio Healthcare System, Cleveland, Ohio

   Run by

   Louis Stokes VA Medical Center

   See if you can join NCT06746623 on ClinicalTrials.gov

6. Reach Through Equitable Implementation in Utah

   The goal of this pragmatic, multilevel Type III Hybrid Effectiveness-Implementation trial is to increase the reach of existing evidence-based interventions (EBIs) for tobacco cessation and to mitigate the impact of adverse Social Drivers of Health (SDOH) among safety-net healthcare system patients …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT06881069 on ClinicalTrials.gov