Surgery Clinical Trials

45 studies are recruiting for surgery in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Implementation Pilot of Preoperative CGA Before Major Surgery

   The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery. The main question it aims to answer is: Can the implementation package help give more people access to this resource? Participants will be in two groups: older adults who…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Wisconsin, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT06184724 on ClinicalTrials.gov

2. Terumo Aortic Global Endovascular Registry

   Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Long Beach Memorial Medical Center, Long Beach, California

   Locations

   58 in total

   Run by

   Vascutek Ltd.

   See if you can join NCT04246463 on ClinicalTrials.gov

3. Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

   The purpose of this study is to determine whether eating solid food prior to undergoing a wide awake local-only no tourniquet (WALANT) procedure reduces anxiety in patients or has any effect on outcomes. Patients will be split randomly into two groups and told whether to eat or fast before their pr…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UCI Health Manchester Pavilion, Orange, California

   Run by

   University of California, Irvine

   See if you can join NCT05819801 on ClinicalTrials.gov

4. Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

   Coagulopathic-induced bleeding after cardiopulmonary bypass in cardiac surgery patients is common and is associated with adverse outcomes in cardiac surgery. The hypothesis of the study is that FEIBA will be a more effective treatment than standard of care (FFP) in cardiac surgery patients who have…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   North Shore University Hospital, Manhasset, New York

   Run by

   Northwell Health

   See if you can join NCT07032792 on ClinicalTrials.gov

5. Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

   This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll. Eligible participants will be randomized to prescription of 1 of 2 groups of medic…

   Stage

   Phase 4

   Ages

   12 to 20

   Site

   Children's Hospital Los Angeles (CHLA), Los Angeles, California

   Locations

   4 in total

   Run by

   University of Michigan

   See if you can join NCT06671002 on ClinicalTrials.gov

6. Green Light for Post-Operative Wellness

   This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside. The primary outcome measure will be pain intensity with secondary outcome measures including opioid requirements, sleep quality, mood, and overall p…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UPMC Shadyside Hospital, Pittsburgh, Pennsylvania

   Run by

   Rebecca E Kotcher, MD

   See if you can join NCT07218289 on ClinicalTrials.gov

7. The Neuralert Stroke Monitor Pilot Trial

   This trial aims to demonstrate that the Neuralert Monitoring System will detect strokes before they would be identified by current standard of care. Each patient will be monitored for up to five days, depending on device connectivity or battery duration. Each monitoring session will consist of wear…

   Stage

   Not phased

   Ages

   22 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Neuralert Technologies LLC

   See if you can join NCT06368193 on ClinicalTrials.gov

8. Prevent Cardiac Surgery Associated AKI Trial

   Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the …

   Stage

   Phase 2

   Ages

   18 to 70

   Site

   George Washington University Hospital, Washington D.C., District of Columbia

   Run by

   George Washington University

   See if you can join NCT06620523 on ClinicalTrials.gov

9. Physical Therapy After Endometriosis Excision

   This is a randomized controlled pilot study comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Quality of life and endometriosis symptoms will be compared following the recovery period.

   Stage

   Not phased

   Ages

   18 to 50

   Site

   Oregon Health & Science University, Portland, Oregon

   Run by

   Oregon Health and Science University

   See if you can join NCT07127783 on ClinicalTrials.gov

10. Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

    The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to repla…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG), San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT05157113 on ClinicalTrials.gov

11. Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)

    This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Fox Chase Cancer Center - Philadelphia, Philadelphia, Pennsylvania

    Run by

    Fox Chase Cancer Center

    See if you can join NCT05454280 on ClinicalTrials.gov

12. Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

    This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor can…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of California, San Diego, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT06784882 on ClinicalTrials.gov

13. The Pediatric Anesthesia Quality Improvement Project

    The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this infor…

    Stage

    Not phased

    Ages

    Up to 21

    Site

    Phoenix Children's Hospital, Phoenix, Arizona

    Locations

    37 in total

    Run by

    The Society for Pediatric Anesthesia

    See if you can join NCT00674388 on ClinicalTrials.gov

14. Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

    The objective is to determine the effectiveness of pulsatile flow during cardiopulmonary bypass to reduce the incidence of acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during c…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    University of Colorado Hospital, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT06349577 on ClinicalTrials.gov

15. Geriatric Thoracic Surgery Ambulation Challenge

    This study is examining collecting data on steps walked (ambulation) per day by thoracic surgery patients over the age of 65 years-old before surgery. The name(s) of the study device involved in this study is: * Fitbit inspire

    Stage

    Not phased

    Ages

    65 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT04630496 on ClinicalTrials.gov

16. Maestro 1.1 Post-Market Registry

    The objective of the study is to observe the real-life usage of the Maestro Platform for surgical assistance in laparoscopic surgery.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Rose Medical Center, Denver, Colorado

    Locations

    12 in total

    Run by

    Moon Surgical

    See if you can join NCT06103136 on ClinicalTrials.gov

17. Ultrasound Evaluation for Improving Patient Selection in vNOTES

    Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is an emerging field in minimally invasive surgery. International consensus-based statement was recently published to help guide the basis for adopting vNOTES into clinical practice, including regarding patient selection. It was agree…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Texas, Houston, Texas

    Run by

    The University of Texas Health Science Center, Houston

    See if you can join NCT05623514 on ClinicalTrials.gov

18. A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery

    Feasibility study of Bevonescein to highlight Nerves and Ureter in patients undergoing Minimally Invasive Surgery

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of California San Diego, San Diego, California

    Run by

    Alume Biosciences, Inc.

    See if you can join NCT06662097 on ClinicalTrials.gov

19. LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors

    Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent m…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT04979156 on ClinicalTrials.gov

20. RCT: Early Feeding After PEG Placement

    Randomized controlled trial to establish evidence on which to base timing of enteral feeding after bedside PEG placement in ventilated Trauma and Surgical ICU patients.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Carilion Roanoke Memorial Hospital, Roanoke, Virginia

    Run by

    Carilion Clinic

    See if you can join NCT04110613 on ClinicalTrials.gov