Surgery Clinical Trials

42 studies are recruiting for surgery in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Collecting Outcomes and Managing Pain After Surgery

   The primary aim of this study is to measure pain and psychosocial patient reported outcomes, objective functionality, and actual daily at home opioid usage in orthopedic patients. The study's goal following the data collection is to predict which patients are at high risk for chronic opioid use.

   Stage

   Not phased

   Ages

   18 to 90

   Site

   Duke Orthopaedics, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT03834818 on ClinicalTrials.gov

2. The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery

   The study is enrolling adults who are scheduled for either inpatient or outpatient elective surgical procedures at The University of Chicago. At pre-operative visits, patients will be consented and a blood sample will be obtained for preemptive genotyping across a panel of actionable germline varia…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University Of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT03729180 on ClinicalTrials.gov

3. The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

   Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful. This study intends to characterize perioperative fasting practices and their potential effects on clinical outcomes th…

   Stage

   Not phased

   Ages

   Any age

   Site

   Mass General Brigham Hospital Network of secondary, tertiary, and quaternary care hospitals, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07022951 on ClinicalTrials.gov

4. Neuralert Stroke Monitor Trial

   The Neuralert monitoring system, a non-invasive device worn on each wrist, is designed to provide continuous monitoring and expedited recognition of stroke by identifying asymmetry in the extremities, facilitating patient treatment and improving outcomes. This study is designed to evaluate the safe…

   Stage

   Not phased

   Ages

   22 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   Neuralert Technologies LLC

   See if you can join NCT07362303 on ClinicalTrials.gov

5. Evaluation of Resection Techniques for Pancreatic Tumors

   The objective of this study is to compare open and minimally invasive pancreatic and liver resection techniques and analyze the different outcome variables from the clinical standpoint. The plan is to investigate patient survival, length of stay, complication rates, operative time, transfusion rate…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Methodist Dallas Medical Center, Dallas, Texas

   Run by

   Methodist Health System

   See if you can join NCT05128890 on ClinicalTrials.gov

6. Implementation Pilot of Preoperative CGA Before Major Surgery

   The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery. The main question it aims to answer is: Can the implementation package help give more people access to this resource? Participants will be in two groups: older adults who…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Wisconsin, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT06184724 on ClinicalTrials.gov

7. Terumo Aortic Global Endovascular Registry

   Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Long Beach Memorial Medical Center, Long Beach, California

   Locations

   58 in total

   Run by

   Vascutek Ltd.

   See if you can join NCT04246463 on ClinicalTrials.gov

8. Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures

   The purpose of this study is to determine whether eating solid food prior to undergoing a wide awake local-only no tourniquet (WALANT) procedure reduces anxiety in patients or has any effect on outcomes. Patients will be split randomly into two groups and told whether to eat or fast before their pr…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UCI Health Manchester Pavilion, Orange, California

   Run by

   University of California, Irvine

   See if you can join NCT05819801 on ClinicalTrials.gov

9. Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

   Coagulopathic-induced bleeding after cardiopulmonary bypass in cardiac surgery patients is common and is associated with adverse outcomes in cardiac surgery. The hypothesis of the study is that FEIBA will be a more effective treatment than standard of care (FFP) in cardiac surgery patients who have…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   North Shore University Hospital, Manhasset, New York

   Run by

   Northwell Health

   See if you can join NCT07032792 on ClinicalTrials.gov

10. Green Light for Post-Operative Wellness

    This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside. The primary outcome measure will be pain intensity with secondary outcome measures including opioid requirements, sleep quality, mood, and overall p…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UPMC Shadyside Hospital, Pittsburgh, Pennsylvania

    Run by

    Rebecca E Kotcher, MD

    See if you can join NCT07218289 on ClinicalTrials.gov

11. The Neuralert Stroke Monitor Pilot Trial

    This trial aims to demonstrate that the Neuralert Monitoring System will detect strokes before they would be identified by current standard of care. Each patient will be monitored for up to five days, depending on device connectivity or battery duration. Each monitoring session will consist of wear…

    Stage

    Not phased

    Ages

    22 and older

    Site

    Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    Neuralert Technologies LLC

    See if you can join NCT06368193 on ClinicalTrials.gov

12. Physical Therapy After Endometriosis Excision

    This is a randomized controlled pilot study comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy. Quality of life and endometriosis symptoms will be compared following the recovery period.

    Stage

    Not phased

    Ages

    18 to 50

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT07127783 on ClinicalTrials.gov

13. Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

    This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty. Investigators will randomize participants to either continuous nerve block or single injection nerve block for the adductor can…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    University of California, San Diego, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT06784882 on ClinicalTrials.gov

14. The Pediatric Anesthesia Quality Improvement Project

    The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this infor…

    Stage

    Not phased

    Ages

    Up to 21

    Site

    Phoenix Children's Hospital, Phoenix, Arizona

    Locations

    37 in total

    Run by

    The Society for Pediatric Anesthesia

    See if you can join NCT00674388 on ClinicalTrials.gov

15. Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

    The objective is to determine the effectiveness of pulsatile flow during cardiopulmonary bypass to reduce the incidence of acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during c…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    University of Colorado Hospital, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT06349577 on ClinicalTrials.gov

16. Geriatric Thoracic Surgery Ambulation Challenge

    This study is examining collecting data on steps walked (ambulation) per day by thoracic surgery patients over the age of 65 years-old before surgery. The name(s) of the study device involved in this study is: * Fitbit inspire

    Stage

    Not phased

    Ages

    65 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT04630496 on ClinicalTrials.gov

17. LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors

    Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent m…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT04979156 on ClinicalTrials.gov