Surgery Clinical Trials

42 studies are recruiting for surgery in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Houston, Texas 8 Philadelphia, Pennsylvania 6 Ann Arbor, Michigan 5 Boston, Massachusetts 5 New York, New York 5 Aurora, Colorado 4 Cincinnati, Ohio 4 St Louis, Missouri 4 Baltimore, Maryland 3 Chapel Hill, North Carolina 3 Charlottesville, Virginia 3 Chicago, Illinois 3 Dallas, Texas 3 Durham, North Carolina 3 Pittsburgh, Pennsylvania 3 Salt Lake City, Utah 3 Washington D.C., District of Columbia 3

Studies now recruiting

  1. FOCUS Pre-Post Study

    The Facilitating Goal-based Conversations for Understanding Surgery (FOCUS) Guide is a communication intervention designed to support discussion and documentation of the goal for surgery during outpatient surgical consultations. The purpose of this study is to assess the efficacy of the FOCUS guide…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Utah Hospital, Salt Lake City, Utah
    Run by
    University of Utah

    See if you can join NCT07664514 on ClinicalTrials.gov

  2. Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

    The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to repla…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG), San Francisco, California
    Run by
    University of California, San Francisco

    See if you can join NCT05157113 on ClinicalTrials.gov

  3. Music Interventions During Wide-Awake Hand Surgery

    The purpose of this study is to examine if patients have a lower anxiety level during wide awake hand surgery while listening to their choice of music vs standardized relaxation music. Patients who are planning to undergo wide awake (local anesthetic only hand surgery) and agree to participate will…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Wisconsin, Madison, Wisconsin
    Run by
    University of Wisconsin, Madison

    See if you can join NCT05472909 on ClinicalTrials.gov

  4. Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

    This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll. Eligible participants will be randomized to prescription of 1 of 2 groups of medic…

    Stage
    Phase 4
    Ages
    12 to 20
    Site
    Children's Hospital Los Angeles (CHLA), Los Angeles, California
    Locations
    9 in total
    Run by
    University of Michigan

    See if you can join NCT06671002 on ClinicalTrials.gov

  5. Prevent Cardiac Surgery Associated AKI Trial

    Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the …

    Stage
    Phase 2
    Ages
    18 to 70
    Site
    George Washington University Hospital, Washington D.C., District of Columbia
    Run by
    George Washington University

    See if you can join NCT06620523 on ClinicalTrials.gov

  6. Maestro 1.1 Post-Market Registry

    The objective of the study is to observe the real-life usage of the Maestro Platform for surgical assistance in laparoscopic surgery.

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Rose Medical Center, Denver, Colorado
    Locations
    12 in total
    Run by
    Moon Surgical

    See if you can join NCT06103136 on ClinicalTrials.gov

  7. Ultrasound Evaluation for Improving Patient Selection in vNOTES

    Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is an emerging field in minimally invasive surgery. An international consensus-based statement was recently published to help guide the basis for adopting vNOTES into clinical practice, including regarding patient selection. It was ag…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Texas, Houston, Texas
    Run by
    The University of Texas Health Science Center, Houston

    See if you can join NCT05623514 on ClinicalTrials.gov

  8. Sentinel Node Biopsy in Endometrial Cancer

    Endometrial cancer (EC) is the most common gynaecological cancer. Current treatment of EC typically includes removal of the uterus and to determine the extent of the disease (removal of fallopian tubes, ovaries \& if required a lymph node dissection (surgical staging)). While lymph node dissection …

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Houston Methodist Hospital, Houston, Texas
    Locations
    23 in total
    Run by
    Queensland Centre for Gynaecological Cancer

    See if you can join NCT04073706 on ClinicalTrials.gov

  9. Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

    The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Arkansas for Medical Sciences (UAMS), Little Rock, Arkansas
    Locations
    24 in total
    Run by
    Washington University School of Medicine

    See if you can join NCT05991453 on ClinicalTrials.gov

  10. Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

    This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal A…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    University of Michigan, Ann Arbor, Michigan
    Locations
    8 in total
    Run by
    University of Michigan

    See if you can join NCT05722002 on ClinicalTrials.gov

  11. AI-driven Clinical Decision Support for Perioperative Blood Orders

    20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion. Presurgical preparation for transfusion is important to allow for safe and timely transfusion during surgery; however, excessive preparation is u…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Washington University / Barnes Jewish Hospital, St Louis, Missouri
    Run by
    Washington University School of Medicine

    See if you can join NCT07223853 on ClinicalTrials.gov

  12. Continuous Versus Intermittent Ward Monitoring

    The investigators will randomize adults having major non-cardiac inpatient surgery to blinded versus unblinded continuous postoperative vital sign monitoring (saturation, ventilation, and heart rate). The investigators will use a wearable, untethered, and battery-powered sensor (Masimo Radius PPG, …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Memorial Hermann Hospital, Houston, Texas
    Locations
    2 in total
    Run by
    The University of Texas Health Science Center, Houston

    See if you can join NCT06232876 on ClinicalTrials.gov

  13. Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.

    The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving recovery in adults undergoing surgery for severe knee arthritis or in…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Walter Reed National Military Medical Center, Bethesda, Maryland
    Run by
    Walter Reed National Military Medical Center

    See if you can join NCT07151417 on ClinicalTrials.gov

  14. Optimizing Pain Self-Management in Total Knee Arthroplasty

    The purpose of this study is to investigate the efficacy of a positive affect enhancing intervention designed to reduce pain and augment reward system function in knee osteoarthritis (KOA) patients undergoing total knee arthroplasty (TKA). The scientific premise is that patient use of a positive em…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Fontaine Research Park, Charlottesville, Virginia
    Run by
    University of Virginia

    See if you can join NCT06038240 on ClinicalTrials.gov

  15. NO During CPB in Neonates to Reduce Risk of AKI

    Acute kidney injury (AKI) following cardiac surgery for congenital heart defects (CHD) in children affects up to 60% of high risk-patients and is a major cause of both short- and long-term morbidity and mortality. Despite effort, to date, no successful therapeutic agent has gained widespread succes…

    Stage
    Phase 3
    Ages
    0 to 0
    Site
    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
    Run by
    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT04216927 on ClinicalTrials.gov

  16. Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation

    Rotator cuff (RC) injuries are particularly prevalent, difficult to repair, and attachment between the bone and tendon is notoriously difficult to achieve. The most common method and current standard of care (SOC) for reattaching connective tissues (e.g., ligaments, tendons) to bone typically invol…

    Stage
    Phase 4
    Ages
    18 to 65
    Site
    10th Medical Group - Air Force Academy, Air Force Academy, Colorado
    Locations
    5 in total
    Run by
    Brooke Army Medical Center

    See if you can join NCT06289686 on ClinicalTrials.gov

  17. Intraoperative Neuromonitoring (IONM) and Bipolar Electrocautery (BE) During Axillary Lymph Node Dissection (ALND)

    The purpose of this study is to determine whether the implementation of existing neurosurgical techniques of intraoperative neuromonitoring (IONM) and the replacement of monopolar electrocautery with bipolar electrocautery (BE), during ALND, will improve the early identification of nerves that have…

    Stage
    Not phased
    Ages
    18 to 70
    Site
    University of Cincinnati, Cincinnati, Ohio
    Run by
    University of Cincinnati

    See if you can join NCT07528638 on ClinicalTrials.gov

  18. Adapting Enhanced Recovery Programs for Low Health Literacy Patients

    Low health literacy patients are a vulnerable population at high-risk for surgical disparities including longer hospital stays, more complications, and more readmissions. This study will adapt enhanced recovery programs (ERPs) to low health literacy patients with a multilevel, health literacy-based…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Alabama at Birmingham, Birmingham, Alabama
    Run by
    University of Alabama at Birmingham

    See if you can join NCT06356558 on ClinicalTrials.gov

  19. A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer

    The purpose of this study is to find out how many participants are interested in a surgical preventive procedure after watching an educational video. Before and after watching the video, participants will complete questionnaires in the clinic.

    Stage
    Not phased
    Ages
    45 and older
    Site
    Johns Hopkins University (Data Collection Only), Baltimore, Maryland
    Locations
    10 in total
    Run by
    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06312124 on ClinicalTrials.gov

  20. Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

    This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Cleveland Clinic Foundation, Cleveland, Ohio
    Run by
    The Cleveland Clinic

    See if you can join NCT06298721 on ClinicalTrials.gov

  21. VR-Based Cognitive Stimulation Games for Delirium Prevention

    This trial aims to evaluate the feasibility, safety, and acceptability of a virtual reality (VR)-based cognitive stimulation game to reduce postoperative delirium among older surgical patients at high risk due to pre-existing cognitive impairment.

    Stage
    Not phased
    Ages
    Up to 65
    Site
    Houston Methodist Hospital, Houston, Texas
    Locations
    2 in total
    Run by
    The Methodist Hospital Research Institute

    See if you can join NCT07641153 on ClinicalTrials.gov

  22. Regular Diet After Colorectal Surgery

    The goal of this pilot study is to assess the safety and feasibility of regular diet after surgical removal of the colon. The study will enroll patients preoperatively, prior to colon surgery, and will follow participants for up to 30 days. The study hypothesizes that simplifying nutritional recomm…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Weill Cornell Medicine-Section of Colon and Rectal Surgery, New York, New York
    Run by
    Weill Medical College of Cornell University

    See if you can join NCT07540845 on ClinicalTrials.gov

  23. Impact of Uterine and Ovarian Vessel Occlusion on Blood Loss in High Burden Minimally Invasive Myomectomy.

    This study hypothesizes that temporary bilateral uterine and utero-ovarian artery occlusion with laparoscopic clamps at time of minimally invasive myomectomy will lead to a decreased blood loss at time of myomectomy compared to minimally invasive myomectomy without temporary occlusion.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Memorial Hermann Hospital, Houston, Texas
    Run by
    The University of Texas Health Science Center, Houston

    See if you can join NCT07182045 on ClinicalTrials.gov

  24. Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis

    This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at Vanderbilt. Outcomes will include intra- and post-operative bleeding and postope…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Vanderbilt University Medical Center, Nashville, Tennessee
    Run by
    Vanderbilt University Medical Center

    See if you can join NCT05774717 on ClinicalTrials.gov

  25. A Study of the Use of 3D Technology to Guide Head and Neck Surgery

    The purpose of this study is to test how the new 3D technology can be used to help improve the surgeon's ability to use information from standard imaging scans to guide head and neck surgery. Researchers will use the Scaniverse app during a standard ultrasound to create 3D images of participants' h…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Memorial Sloan Kettering at Basking Ridge (Consent Only), Basking Ridge, New Jersey
    Locations
    7 in total
    Run by
    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06676592 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.