Suicide Clinical Trials

42 studies are recruiting for suicide in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Youth Empowerment and Safety Intervention

   This clinical trial will implement and evaluate the feasibility, acceptability, and initial impact of Peer Support Specialist (PSS) services for public system-involved sexual and gender minority (lesbian, gay, bisexual, queer and/or transgender) youth (SGMY) at risk of suicide.

   Stage

   Not phased

   Ages

   12 to 17

   Site

   Case Western Reserve University, Cleveland, Ohio

   Run by

   Case Western Reserve University

   See if you can join NCT07214233 on ClinicalTrials.gov

2. Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

   There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who p…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   University of Kansas Medical Center Emergency Department, Kansas City, Kansas

   Locations

   2 in total

   Run by

   Lindsay Maguire, MD

   See if you can join NCT06085937 on ClinicalTrials.gov

3. Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b

   This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing the acceptability, feasibility, and preliminary effectiveness of the combination of two psychosocial interventions, Cog…

   Stage

   Not phased

   Ages

   12 and older

   Site

   Children's Hospital of Michigan (CHM) Emergency Department, Detroit, Michigan

   Locations

   2 in total

   Run by

   University of Michigan

   See if you can join NCT07506460 on ClinicalTrials.gov

4. Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans

   Mental health care for Veterans with suicidal symptoms is of paramount import to the VA. Unfortunately, VA suicide reports show suicide rates increasing, suggesting a need for enhancing current VA suicide mental health care efforts. While several psychotherapeutic treatments exist for acute suicida…

   Stage

   Not phased

   Ages

   18 and older

   Site

   James J. Peters VA Medical Center, Bronx, NY, The Bronx, New York

   Run by

   VA Office of Research and Development

   See if you can join NCT04731519 on ClinicalTrials.gov

5. A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

   Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death among youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be used to provide a unique understanding of risk factors, including psychol…

   Stage

   Not phased

   Ages

   13 to 18

   Site

   Columbia University, New York, New York

   Run by

   Ksana Health

   See if you can join NCT05920252 on ClinicalTrials.gov

6. Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

   This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Eastern Colorado Health Care System, Aurora, Colorado

   Run by

   VA Eastern Colorado Health Care System

   See if you can join NCT06375083 on ClinicalTrials.gov

7. Suicide Risk Interventions

   The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Run by

   VA Office of Research and Development

   See if you can join NCT05931289 on ClinicalTrials.gov

8. Real-time Examination of Skills and Coping Use in Teen's Everyday Lives

   The goal of this clinical trial is to compare two core intervention skills among adolescents with a history of engaging in at least 3 lifetime incidents of self-inflicted injury (SII), at least one of which was a suicide attempt of at least moderate lethality and moderate intent to die. The main qu…

   Stage

   Not phased

   Ages

   13 to 18

   Site

   University of Utah, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT06720753 on ClinicalTrials.gov

9. Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

   This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 13-24 who present to the Emergency Department (ED) with suicidal ideation or behavior. Outcomes will be monitored at baseline and at 3, 6 \& 12 month follow-up assessments.

   Stage

   Phase 2

   Ages

   13 to 24

   Site

   Ronald Reagan Medical Center, Los Angeles, California

   Locations

   5 in total

   Run by

   University of California, Los Angeles

   See if you can join NCT05304065 on ClinicalTrials.gov

10. Text-based Support for Parents of Adolescents Following an Emergency Department Visits

    The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.

    Stage

    Not phased

    Ages

    13 and older

    Site

    University of Michigan, Ann Arbor, Michigan

    Locations

    2 in total

    Run by

    University of Michigan

    See if you can join NCT06660199 on ClinicalTrials.gov

11. Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

    The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use with this population to use in primary care via telehealth and will r…

    Stage

    Not phased

    Ages

    18 to 24

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Locations

    3 in total

    Run by

    Elizabeth Arnold

    See if you can join NCT05869552 on ClinicalTrials.gov

12. Just-in-time Interventions for Reducing Short-term Suicide Risk

    The goal of this study is to test the effects of just-in-time intervention strategies aimed to promote implementation of the safety plan and its components at different levels of suicidal urges and intent. The main questions the investigators aim to answer are: 1. What is the acceptability and feas…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Mass General Brigham, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT05793541 on ClinicalTrials.gov

13. Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

    Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today. For example, in 2018 suicide was reported as the 2nd leading cause of death among Black Americans ages 10 to14 years old. Findings yielded fro…

    Stage

    Not phased

    Ages

    11 to 15

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT07125144 on ClinicalTrials.gov

14. Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)

    The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary outcomes (i.e., suicidal ideation and behavior; re-hospitalization).

    Stage

    Not phased

    Ages

    18 to 26

    Site

    Butler Hospital, Providence, Rhode Island

    Run by

    Butler Hospital

    See if you can join NCT05180344 on ClinicalTrials.gov

15. e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide

    The investigators propose to create e-Connect, a new service delivery model that will enable real time identification and targeted, county-specific referral and linkage of participants with suicidal behavior (SB) and related behavioral health (BH) problems. e-Connect will: (i) establish and formali…

    Stage

    Not phased

    Ages

    10 and older

    Site

    Columbia University, New York, New York

    Run by

    Columbia University

    See if you can join NCT03586895 on ClinicalTrials.gov

16. Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

    Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents. Although death by firearm remains the most common cause of suicide in the United States, an intentional overdose of substance usage such as pre…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    The Menninger Clinic, Houston, Texas

    Run by

    Baylor College of Medicine

    See if you can join NCT05489042 on ClinicalTrials.gov

17. Reaching Out to Distressed Medical Residents, Fellows and Faculty

    The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and suicidal thoughts. The screening and ability to interact online with …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Oregon Health and Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT02010866 on ClinicalTrials.gov