Suicidal Ideation Clinical Trials

50 studies are recruiting for suicidal ideation in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

   There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who p…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   University of Kansas Medical Center Emergency Department, Kansas City, Kansas

   Locations

   2 in total

   Run by

   Lindsay Maguire, MD

   See if you can join NCT06085937 on ClinicalTrials.gov

2. Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury

   The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI). These conditions have been shown to be linked. The investigators are using a hig…

   Stage

   Phase 1

   Ages

   22 to 65

   Site

   Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois

   Run by

   VA Office of Research and Development

   See if you can join NCT05647044 on ClinicalTrials.gov

3. Flourish in Schools Pilot Study

   This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1. Examine if Flourish is effective and can be feasibly delivered within schools among middle and high school students who are experiencing cyberbullying…

   Stage

   Not phased

   Ages

   11 to 21

   Site

   Bay Village School District, Bay Village, Ohio

   Locations

   2 in total

   Run by

   Candice Biernesser

   See if you can join NCT07506525 on ClinicalTrials.gov

4. MicroRNA Correlates of Childhood Maltreatment and Suicidality

   This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g. miRNA [MiRNA]) levels. miRNAs are a type of RNA (genetic material that is translated into…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   2 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04923685 on ClinicalTrials.gov

5. Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

   The investigators hypothesized that during the 9-week course of Engage \& Connect treatment there will be an increase in brain functions of the Positive Valence System which in turn will lead to reduction in suicidality.

   Stage

   Not phased

   Ages

   50 to 80

   Site

   Weill Cornell Medicine, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT05925322 on ClinicalTrials.gov

6. Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk

   The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts. The treatment is non-invasive (does not involve surgery or medications), is given over 5 days, and uses brai…

   Stage

   Not phased

   Ages

   15 to 25

   Site

   UC Davis Medical Center, Sacramento, California

   Run by

   University of California, Davis

   See if you can join NCT07025720 on ClinicalTrials.gov

7. Cannabis, Linked Emotions, and Adolescent Risk Study

   The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of …

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Massachusetts General Hopsital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06576076 on ClinicalTrials.gov

8. Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

   The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for posttraumatic stress disorder (PTSD), will reduce suicidal thoughts and b…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Carl R. Darnall Army Medical Center, Fort Hood, Texas

   Run by

   Ohio State University

   See if you can join NCT07238192 on ClinicalTrials.gov

9. Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

   This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with productive time in the Emergency Departments (EDs). The EBPs satisfy several…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UMass Memorial Health, Worcester, Massachusetts

   Run by

   University of Massachusetts, Worcester

   See if you can join NCT06223867 on ClinicalTrials.gov

10. Assessment of Emotion Regulation Strategies Used When Suicidal

    Crisis Response Planning is an efficacious, one-session intervention that increases positive affect, decreases negative affect and psychiatric hospitalizations, and reduces suicide attempts by 76% among Servicemembers. Crisis Response Planning is hypothesized to reduce suicidality by identifying a …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University Wexner Medical Center, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT05722197 on ClinicalTrials.gov

11. Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic Stimulation

    Evaluate the feasibility, safety, and preliminary efficacy of deep Transcranial Magnetic Stimulation (dTMS) as an adjunctive treatment for adolescents hospitalized with major depressive disorder (MDD).

    Stage

    Not phased

    Ages

    14 to 18

    Site

    Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT07217444 on ClinicalTrials.gov

12. Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior

    This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change strategies for adolescents at risk of suicidal behavior who suffer from d…

    Stage

    Not phased

    Ages

    11 to 18

    Site

    Nationwide Children's Hospital, Columbus, Ohio

    Run by

    Jeff Bridge

    See if you can join NCT05390918 on ClinicalTrials.gov

13. Teen Recovery Through Inspiration, Support, and Empowerment

    The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility. The intervention aims to reduce suicidality, depression, anxiety, re-hospitalization, and to imp…

    Stage

    Not phased

    Ages

    15 to 18

    Site

    The University of Texas Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT07170657 on ClinicalTrials.gov

14. Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans

    Suicide prevention is a top priority for VA as all continue to seek new and inventive ways to reduce suicide rates among Veterans. Many experts agree that suicide prevention efforts could be improved by making suicide-specific interventions easier to access. The current project aims to move toward …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Southeast Louisiana Veterans Health Care System, New Orleans, LA, New Orleans, Louisiana

    Run by

    VA Office of Research and Development

    See if you can join NCT05884476 on ClinicalTrials.gov

15. Advancing Suicide Intervention Strategies for Teens During High Risk Periods

    To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.

    Stage

    Not phased

    Ages

    11 to 17

    Site

    Nationwide Children's, Columbus, Ohio

    Locations

    2 in total

    Run by

    Seattle Children's Hospital

    See if you can join NCT05078970 on ClinicalTrials.gov

16. Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

    The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use with this population to use in primary care via telehealth and will r…

    Stage

    Not phased

    Ages

    18 to 24

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Locations

    3 in total

    Run by

    Elizabeth Arnold

    See if you can join NCT05869552 on ClinicalTrials.gov

17. Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI

    This is a prospective clinical trial to confirm the effectiveness of bilateral accelerated theta burst stimulation (aTBS) on suicidal ideation (SI), while exploring cortical inhibition measures in this treatment paradigm. In this proposed study, the investigators will evaluate the anti-suicidal eff…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    UCSD Interventional Psychiatry, San Diego, California

    Run by

    University of California, San Diego

    See if you can join NCT05377177 on ClinicalTrials.gov

18. Effect of Morning Light Exposure on Mood

    Mood dysregulation and suicidal ideation are closely associated with disruption of sleep and circadian rhythms. Moreover, sleep problems and circadian disruption are commonplace features of military life. Critically, specifically timed light exposure plays a powerful role in regulating mood, circad…

    Stage

    Not phased

    Ages

    18 to 60

    Site

    University of Arizona, Tucson, Arizona

    Run by

    University of Arizona

    See if you can join NCT05616819 on ClinicalTrials.gov

19. Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates

    Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional awareness, and understanding the self in relation to others. The compara…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Auburn University, Auburn, Alabama

    Run by

    Auburn University

    See if you can join NCT05285111 on ClinicalTrials.gov

20. Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

    Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today. For example, in 2018 suicide was reported as the 2nd leading cause of death among Black Americans ages 10 to14 years old. Findings yielded fro…

    Stage

    Not phased

    Ages

    11 to 15

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT07125144 on ClinicalTrials.gov

21. Stepped Approach to Reducing Risk of Suicide in Primary Care

    Suicide is the second leading cause of death among young people aged 12-17 years in the United States, yet many youth at risk for suicide are not identified or go untreated. Stepped care approaches have been shown to be effective at reducing suicide risk in clinical settings, including primary care…

    Stage

    Not phased

    Ages

    12 to 17

    Site

    AxessPointe Community Health Centers/Health Quarters, Akron, Ohio

    Locations

    15 in total

    Run by

    Cynthia Fontanella

    See if you can join NCT06018285 on ClinicalTrials.gov

22. Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)

    The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary outcomes (i.e., suicidal ideation and behavior; re-hospitalization).

    Stage

    Not phased

    Ages

    18 to 26

    Site

    Butler Hospital, Providence, Rhode Island

    Run by

    Butler Hospital

    See if you can join NCT05180344 on ClinicalTrials.gov

23. Swift Outpatient Alternatives for Rapid Stabilization

    The goal of this clinical trial is to improve the effective outpatient management of acute youth suicide risk by optimizing intervention components to build an efficient, evidence-based intervention that is responsive to the needs of, and coordinated with, providers in primary care settings. The ma…

    Stage

    Not phased

    Ages

    13 to 21

    Site

    Seattle Children's, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT05996172 on ClinicalTrials.gov

24. Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization

    Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization. The investigators propose testing a brief, scalable intervention using evaluative conditioning aimed at reducing suicidal thoughts a…

    Stage

    Not phased

    Ages

    12 to 19

    Site

    Franciscan Hospital For Children, Inc., Brighton, Massachusetts

    Run by

    Franciscan Hospital For Children, INC.

    See if you can join NCT05796531 on ClinicalTrials.gov

25. Suicide Treatment Alternatives for Teens

    Quasi-Randomized trial to compare inpatient care versus outpatient crisis intervention clinic. This study plans to enroll up to 1,000 participants across 4 sites in a 5 years period.

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Northwell Health, Glen Oaks, New York

    Locations

    4 in total

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT04089254 on ClinicalTrials.gov