Spinal Cord Injury Clinical Trials

46 studies are recruiting for spinal cord injury in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Chicago, Illinois 5 Cleveland, Ohio 5 Houston, Texas 5 West Orange, New Jersey 4 Pittsburgh, Pennsylvania 3 The Bronx, New York 3

Studies, page 2

  1. Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)

    The purpose of this research study is to measure the tolerability and preliminary efficacy of a drug, galantamine, to treat metabolic syndrome (MetS) by reducing circulating inflammation in people with spinal cord injury (SCI). Galantamine is FDA-approved for the treatment of Alzheimer's disease. H…

    Stage
    Phase 2
    Ages
    21 to 75
    Site
    Northwell Health, Manhasset, New York
    Locations
    3 in total
    Run by
    Northwell Health

    See if you can join NCT07625332 on ClinicalTrials.gov

  2. Tele-Exercise to Promote Empowered Movement in Individuals With Spinal Cord Injury

    To achieve our specific aims and hypotheses we will conduct a parallel group mixed methods randomized control trial comparing participation in the TEEMS program with exercise via asynchronous video library equivalent (control). The use of mixed methods will allow for the integration of quantitative…

    Stage
    Not phased
    Ages
    18 to 75
    Site
    Drexel University Health Science Building, Philadelphia, Pennsylvania
    Run by
    Drexel University

    See if you can join NCT07022808 on ClinicalTrials.gov

  3. Cortical Recording and Stimulating Array Brain-Machine Interface

    The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.

    Stage
    Not phased
    Ages
    22 to 70
    Site
    University of Chicago, Chicago, Illinois
    Locations
    2 in total
    Run by
    Michael Boninger

    See if you can join NCT01894802 on ClinicalTrials.gov

  4. Clinical Outcome Assessment for AT & BCI

    Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers. Clinicians and researchers currently lack a common framework to objectively quantify how much a given AT or BCI improves …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Shirley Ryan AbilityLab, Chicago, Illinois
    Run by
    Shirley Ryan AbilityLab

    See if you can join NCT07407725 on ClinicalTrials.gov

  5. Non-invasive Spinal Cord Stimulation and Blood Pressure Regulation After Spinal Cord Injury

    The goal of this clinical trial is to learn if non-invasive spinal cord stimulation intervention improves blood pressure regulation in individuals with chronic spinal cord injury. The main questions it aims to answer are: * Can site specific spinal cord stimulation enhance blood pressure regulation…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Frazier Rehabilitation Institute, Louisville, Kentucky
    Locations
    2 in total
    Run by
    University of Louisville

    See if you can join NCT07504055 on ClinicalTrials.gov

  6. Neuromodulation to Improve Grasping Function After SCI

    The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI. The main question it aims to answer is if the inputs to late descending signals above…

    Stage
    Not phased
    Ages
    18 to 75
    Site
    The State University of New York at Buffalo, Buffalo, New York
    Run by
    State University of New York at Buffalo

    See if you can join NCT07433959 on ClinicalTrials.gov

  7. Virtual Peer Coaching in Manual Wheelchair Skills

    The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained. Then, trainees will be enrolled into one of three interventions: intervention with remote feedback (Group 1), and a wait list control …

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Pittsburgh, Pittsburgh, Pennsylvania
    Run by
    University of Pittsburgh

    See if you can join NCT06295146 on ClinicalTrials.gov

  8. MEP Up-conditioning to Target Corticospinal Plasticity

    Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist extensor). Investigators will assess the impact of the brain stimulation trai…

    Stage
    EARLY_Phase 1
    Ages
    18 and older
    Site
    Medical University of South Carolina, Charleston, South Carolina
    Run by
    Medical University of South Carolina

    See if you can join NCT06989905 on ClinicalTrials.gov

  9. CE-STAND: Cervical Epidural STimulation After Neurologic Damage

    CE-STAND aims to address three areas under-represented in research: chronic, cervical, and autonomic dysfunction. It is both significant and highly impactful, as treating autonomic dysfunction could substantially improve function and quality of life (QoL) in chronic cervical SCI patients.

    Stage
    Phase 1
    Ages
    22 and older
    Site
    University of Minnesota, Minneapolis, Minnesota
    Run by
    University of Minnesota

    See if you can join NCT06410001 on ClinicalTrials.gov

  10. Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis

    This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves functional arm/hand movements in individuals with paralysis or paresis due t…

    Stage
    EARLY_Phase 1
    Ages
    18 to 75
    Site
    Northwell Health's The Feinstein Institute for Medical Research, Manhasset, New York
    Run by
    Northwell Health

    See if you can join NCT04755699 on ClinicalTrials.gov

  11. VR Mindfulness Training for Veterans With SCI

    This study involves delivering a mindfulness program that was developed for Veterans called VA Compassionate Awareness Learning Module (VA CALM) to Veterans with spinal cord injuries (SCI) to develop accommodations to make the VA CALM program more accessible for those with SCI. It will involve deli…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
    Run by
    VA Office of Research and Development

    See if you can join NCT06587607 on ClinicalTrials.gov

  12. Improving Bladder Function in SCI by Neuromodulation

    This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury.

    Stage
    Not phased
    Ages
    18 to 45
    Site
    University of California, Los Angeles, Los Angeles, California
    Run by
    University of California, Los Angeles

    See if you can join NCT02331979 on ClinicalTrials.gov

  13. A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury

    The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI). LCTOPC1 is designed to replace or support cells that are absent or dysfunctional due to traumatic injury, with a g…

    Stage
    Phase 1
    Ages
    18 to 65
    Site
    University of California, San Diego, La Jolla, California
    Locations
    2 in total
    Run by
    Lineage Cell Therapeutics, Inc.

    See if you can join NCT06841770 on ClinicalTrials.gov

  14. Self-balancing Personal Exoskeleton for SCI (WINY)

    This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

    Stage
    Not phased
    Ages
    18 and older
    Site
    Walk in New York (WINY) Physical Therapy, P.C., New York, New York
    Run by
    Wandercraft

    See if you can join NCT07222033 on ClinicalTrials.gov

  15. Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia

    In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after cervical SCI; and 2) Maximize the recovery of reaching and grasping pote…

    Stage
    Not phased
    Ages
    18 to 70
    Site
    Shirley Ryan AbilityLab, Chicago, Illinois
    Locations
    2 in total
    Run by
    VA Office of Research and Development

    See if you can join NCT05157282 on ClinicalTrials.gov

  16. Exoskeleton and Spinal Cord Stimulation for SCI

    The overall aim of this project is to assess the effect of combining transcutaneous lumbosacral stimulation (TLS) during Exoskeleton Assisted Walking (EAW) compared to EAW alone without stimulation on walking recovery.

    Stage
    Not phased
    Ages
    18 to 65
    Site
    Kessler Foundation, West Orange, New Jersey
    Run by
    Kessler Foundation

    See if you can join NCT03096197 on ClinicalTrials.gov

  17. Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury

    Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury. While some scientists have begun to study the effect of electrical stimulation on patient's ability to walk and move their legs after lower spinal cor…

    Stage
    Not phased
    Ages
    18 and older
    Site
    NewYork-Presbyterian Hospital / Columbia University Irving Medical Center (NYPH/CUIMC), New York, New York
    Locations
    2 in total
    Run by
    Jason Carmel

    See if you can join NCT06867809 on ClinicalTrials.gov

  18. SCI&U Peer Health Coaching Program for Individuals Newly Discharged From Inpatient Rehabilitation

    The goal of this clinical trial is to learn if the online program and web-based platform for delivery of self-management services to people with spinal cord injury (SCI) called "SCI \& U" can support transitions from hospital to the community after injury. Specifically, can providing support from t…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Spinal Cord Injury Association of Connecticut, Milford, Connecticut
    Locations
    2 in total
    Run by
    University of Toronto

    See if you can join NCT06677905 on ClinicalTrials.gov

  19. Improve Dynamic Lateral Balance of Humans With SCI

    This study is to test whether pelvis perturbation training paired with transcutaneous spinal direct current stimulation (tsDCS) will be effective in improving dynamic balance and locomotor function in humans with SCI. One group will receive pelvis perturbation training paired with tsDCS, one group …

    Stage
    Not phased
    Ages
    18 to 65
    Site
    Abilitylab, Chicago, Illinois
    Run by
    Shirley Ryan AbilityLab

    See if you can join NCT02991248 on ClinicalTrials.gov

  20. Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

    This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunct…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    North Florida/South Georgia Veterans Health System, Gainesville, Florida
    Locations
    2 in total
    Run by
    North Florida Foundation for Research and Education

    See if you can join NCT04460872 on ClinicalTrials.gov

  21. Spinal Cord Injury Registry - North American Clinical Trials Network

    The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI). Information will be collected on the natural hi…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Miami, Miami, Florida
    Locations
    14 in total
    Run by
    Robert G. Grossman, MD

    See if you can join NCT00178724 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.