Smoking Cessation Clinical Trials

59 studies are recruiting for smoking cessation in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. CONNECTing to LungCare

   This study evaluates a smoking cessation intervention (CONNECTing to LungCare) for improving shared decision-making conversations about smoking cessation and lung cancer screening between patients and providers. Shared decision making is a patient care model in which providers offer information reg…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT06213532 on ClinicalTrials.gov

2. Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

   This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smok…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07049757 on ClinicalTrials.gov

3. Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

   This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.

   Stage

   Not phased

   Ages

   21 and older

   Site

   Brown University, Providence, Rhode Island

   Run by

   Brown University

   See if you can join NCT06948058 on ClinicalTrials.gov

4. Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

   This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care among cancer survivors who smoke cigarettes and engage in at-risk alcohol use. Investigators will evaluate implementation outcomes through structured stakeholder …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Moffitt Cancer Center, Tampa, Florida

   Run by

   H. Lee Moffitt Cancer Center and Research Institute

   See if you can join NCT07447635 on ClinicalTrials.gov

5. Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt

   Smoking is the leading preventable cause of death in the United States, and quitting is especially difficult for couples who both smoke. When both partners smoke, they are less likely to quit successfully and more likely to relapse compared to people whose partner does not smoke. Research suggests …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Colorado Denver, Denver, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT07553962 on ClinicalTrials.gov

6. Empowering Cessation ACS South Region

   Sexual and/or gender minority (SGM) people face a disproportionate burden of cancer risk, and tobacco use is a key modifiable risk factor. SGM tobacco-related disparities are especially pronounced in places with high levels of stigma against SGM people. This community-engaged and remotely-delivered…

   Stage

   Phase 2

   Ages

   18 to 100

   Site

   University of Oklahoma Health Campus, Oklahoma City, Oklahoma

   Run by

   University of Oklahoma

   See if you can join NCT06820034 on ClinicalTrials.gov

7. Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

   This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA strategies using multilevel interventions that impact determinants of …

   Stage

   Not phased

   Ages

   50 to 80

   Site

   LSUHSC School of Public Health, New Orleans, Louisiana

   Locations

   2 in total

   Run by

   Louisiana State University Health Sciences Center in New Orleans

   See if you can join NCT07576595 on ClinicalTrials.gov

8. Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

   The goal of this clinical trial is to improve cancer patient's health, survival, and quality of life by dispelling risk behaviors for Northwestern Memorial Health Care (NMHC) patients who are cancer survivors. The main question[s] STELLAR aims to answer are: * How best to combine three behavior int…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northwestern University-Feinberg School of Medicine, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT05687604 on ClinicalTrials.gov

9. Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors

   The purpose of the study is to develop a new quit-smoking treatment among individuals with a cancer diagnosis using a smartphone app.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Institute for Nicotine & Tobacco Studies, New Brunswick, New Jersey

   Run by

   Rutgers, The State University of New Jersey

   See if you can join NCT07210567 on ClinicalTrials.gov

10. A Culturally Tailored Smartphone Application for African American Smokers

    The overall objectives of this research proposal, are to (a) create a smartphone application for smoking cessation (i.e., HealthyCells), which will be achieved by integrating two pre-existing evidence-based smartphone interventions, (b) create culturally tailored treatment content (i.e., messages, …

    Stage

    Not phased

    Ages

    18 and older

    Site

    TSET Health Promotion Research Center, Oklahoma City, Oklahoma

    Run by

    University of Oklahoma

    See if you can join NCT05188287 on ClinicalTrials.gov

11. Bladder Cancer Screening Trial

    There is currently no accepted screening strategy for patients at high risk of developing bladder cancer. This study will ask patients to complete a urine test every 6 months for 2 years to help assess if routine screening helps finding bladder cancer at an earlier stage.

    Stage

    Not phased

    Ages

    50 and older

    Site

    University of Texas Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT05646485 on ClinicalTrials.gov

12. Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

    The purpose of this study is to refine and pilot an intervention using the Nicotine Metabolite Ratio (NMR) to inform the selection of pharmacologic treatment to increase smoking abstinence among Alaska Native and American Indian people. This is a single-arm pilot trial to assess and improve accepta…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Anchorage Native Primary Care Center, Anchorage, Alaska

    Run by

    Southcentral Foundation

    See if you can join NCT06556238 on ClinicalTrials.gov

13. Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

    The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia. The main questions it aims to answer are: * Is QuitAid, alone or combined wi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT05660525 on ClinicalTrials.gov

14. The Avenues Study: Dual Use Cessation

    The overarching goal of this research is to determine the most effective approach for helping dual users of cigarettes and electronic nicotine delivery systems (ENDS) quit smoking. 500 participants will be enrolled and can expect to be on study for 12 months.

    Stage

    Phase 4

    Ages

    21 and older

    Site

    University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin

    Run by

    University of Wisconsin, Madison

    See if you can join NCT06474299 on ClinicalTrials.gov

15. Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

    This study's long-term goal is to improve clinical outcomes among smokers living with HIV (SLWH) by providing smoking cessation interventions in HIV clinical care that will increase the chances of quitting smoking, limits costs and burden on staff and reach many smokers living with HIV.

    Stage

    Phase 4

    Ages

    18 and older

    Site

    New York University School of Global Public Health, New York, New York

    Run by

    New York University

    See if you can join NCT06598397 on ClinicalTrials.gov

16. Quitxt Mobile Text Messaging Cessation Research Study

    The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke. The goal of the proposed study is to evaluate the effectiveness of the bilingual and culturally tailored Quitxt mobile ces…

    Stage

    Not phased

    Ages

    18 to 29

    Site

    The University of Texas Health Science Center at San Antonio, San Antonio, Texas

    Run by

    The University of Texas Health Science Center at San Antonio

    See if you can join NCT05958667 on ClinicalTrials.gov

17. ACT Lung Health Intervention: Phase Two

    This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT06945120 on ClinicalTrials.gov

18. Enhancing Smoking Cessation Via Telehealth Options in Primary Care

    The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking about smoking history, motivation to …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT05493254 on ClinicalTrials.gov

19. Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

    The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation across rural primary care settings. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking ab…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT05764759 on ClinicalTrials.gov

20. Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment

    This study will evaluate the efficacy of extended bupropion(6 months) versus standard bupropion treatment (7 weeks) among African American daily smokers.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Missouri

    Run by

    University of Kansas Medical Center

    See if you can join NCT05732272 on ClinicalTrials.gov

21. Tobacco Education and Lung Health Study (TEAL)

    Primary Objective To compare two smoking cessation interventions among individuals undergoing lung cancer screening. Primary outcomes are: 3-month self-reported abstinence from cigarettes and 6-month self-reported and bioverified abstinence from cigarettes. Secondary Objectives 1) To evaluate reach…

    Stage

    Phase 3

    Ages

    50 to 80

    Site

    Georgetown University Medical Center, Washington D.C., District of Columbia

    Run by

    Georgetown University

    See if you can join NCT06290869 on ClinicalTrials.gov

22. Take A Break - Rural

    The study team proposes a multi-level trial to test 1) novel implementation programs in rural counties designed to increase access to 2) recent advances in tobacco control services for people who are not-yet-ready-to-quit smoking. In this field, most trials have focused only on those already ready-…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wake Forest University Health Sciences, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT05790486 on ClinicalTrials.gov

23. Veteran Social Support for Enhancing Use of Smoking Cessation Treatment

    This study is recruiting Veterans who currently smoke cigarettes and support persons who are nominated by the Veterans. The purpose of this study is to assist Veterans with smoking cessation by asking Veterans to choose a support person who will assist them with the quitting process, or who may ass…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota

    Run by

    VA Office of Research and Development

    See if you can join NCT05868421 on ClinicalTrials.gov

24. Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study

    Tobacco use remains the leading cause of death in the United States and contributes to more than 7 million hospitalizations annually. Being admitted to the hospital offers the perfect opportunity to support smoking cessation. Patients are motivated to quit because of their current illness and socie…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Baystate Medical Center, Springfield, Massachusetts

    Run by

    Baystate Medical Center

    See if you can join NCT05733767 on ClinicalTrials.gov

25. Quitting Matters Human Immunodeficiency Virus Hybrid Trial

    The purpose of this study is to compare the advantages and disadvantages of two approaches for quitting smoking among people living with HIV (PWH). Participants will complete a 24- week (~6-month) study where the Participants will be assigned to one of two smartphone apps to help with quitting smok…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wake Forest University, Implementation Science, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT06883097 on ClinicalTrials.gov