Smoking Cessation Clinical Trials

60 studies are recruiting for smoking cessation in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

   The investigators aim to address the following specific aims: * Determine the efficacy of Prog in preventing postpartum smoking relapse and reducing smoking relapse risk factors. * Examine the effects of this maternal smoking intervention on infant health. * Examine racial and ethnic differences in…

   Stage

   Phase 4

   Ages

   18 to 45

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT04783857 on ClinicalTrials.gov

2. American Indian Smokefree Native RCT

   The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Masonic Cancer Center, Minneapolis, Minnesota

   Run by

   Masonic Cancer Center, University of Minnesota

   See if you can join NCT06544811 on ClinicalTrials.gov

3. Preliminary Effectiveness of Enhanced Text Message + Incentives

   This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives. The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT07420621 on ClinicalTrials.gov

4. Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

   The goal of this study is to: partner with Respiratory Health Association and determine barriers and unmet smoking cessation treatment needs from leaders in behavioral health organizations, treatment programs and adults who smoke (AWS) in Chicago. This will be accomplished by establishing a communi…

   Stage

   Not phased

   Ages

   18 to 26

   Site

   The University of Chicago, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06837220 on ClinicalTrials.gov

5. Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum

   Using both tobacco and cannabis during pregnancy is more common in minoritized groups and can make quitting smoking in pregnancy and remaining smoke free postpartum difficult. Investigators will test an intervention to address prenatal depressive symptoms to encourage people to quit tobacco and can…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Bellefield Towers, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07489443 on ClinicalTrials.gov

6. PASCAL Feasibility Study

   The goal of this randomized study is to assess if a conversational agent (or chatbot) that the investigators have developed to help with quitting smoking is acceptable to people trying to quit smoking and to also collect initial information regarding its effectiveness. In this study, some participa…

   Stage

   Not phased

   Ages

   21 and older

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT07301151 on ClinicalTrials.gov

7. The Options 2 Study

   The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products. Participants will: * Use nicotine pouches, nicotine mini lozenges, or no stud…

   Stage

   Phase 4

   Ages

   21 and older

   Site

   University of Wisconsin, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT06595459 on ClinicalTrials.gov

8. Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities

   This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the smoke has cleared (third-hand smoke (THS)) among Chinese American smok…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07049757 on ClinicalTrials.gov

9. Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

   This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.

   Stage

   Not phased

   Ages

   21 and older

   Site

   Brown University, Providence, Rhode Island

   Run by

   Brown University

   See if you can join NCT06948058 on ClinicalTrials.gov

10. Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

    This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care among cancer survivors who smoke cigarettes and engage in at-risk alcohol use. Investigators will evaluate implementation outcomes through structured stakeholder …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Moffitt Cancer Center, Tampa, Florida

    Run by

    H. Lee Moffitt Cancer Center and Research Institute

    See if you can join NCT07447635 on ClinicalTrials.gov

11. Measuring Communal Coping in Dual-smoking Couples Making a Quit Attempt

    Smoking is the leading preventable cause of death in the United States, and quitting is especially difficult for couples who both smoke. When both partners smoke, they are less likely to quit successfully and more likely to relapse compared to people whose partner does not smoke. Research suggests …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Colorado Denver, Denver, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT07553962 on ClinicalTrials.gov

12. Empowering Cessation ACS South Region

    Sexual and/or gender minority (SGM) people face a disproportionate burden of cancer risk, and tobacco use is a key modifiable risk factor. SGM tobacco-related disparities are especially pronounced in places with high levels of stigma against SGM people. This community-engaged and remotely-delivered…

    Stage

    Phase 2

    Ages

    18 to 100

    Site

    University of Oklahoma Health Campus, Oklahoma City, Oklahoma

    Run by

    University of Oklahoma

    See if you can join NCT06820034 on ClinicalTrials.gov

13. Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

    This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA strategies using multilevel interventions that impact determinants of …

    Stage

    Not phased

    Ages

    50 to 80

    Site

    LSUHSC School of Public Health, New Orleans, Louisiana

    Locations

    2 in total

    Run by

    Louisiana State University Health Sciences Center in New Orleans

    See if you can join NCT07576595 on ClinicalTrials.gov

14. Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

    The goal of this clinical trial is to improve cancer patient's health, survival, and quality of life by dispelling risk behaviors for Northwestern Memorial Health Care (NMHC) patients who are cancer survivors. The main question[s] STELLAR aims to answer are: * How best to combine three behavior int…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northwestern University-Feinberg School of Medicine, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT05687604 on ClinicalTrials.gov

15. Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors

    The purpose of the study is to develop a new quit-smoking treatment among individuals with a cancer diagnosis using a smartphone app.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Institute for Nicotine & Tobacco Studies, New Brunswick, New Jersey

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT07210567 on ClinicalTrials.gov

16. A Culturally Tailored Smartphone Application for African American Smokers

    The overall objectives of this research proposal, are to (a) create a smartphone application for smoking cessation (i.e., HealthyCells), which will be achieved by integrating two pre-existing evidence-based smartphone interventions, (b) create culturally tailored treatment content (i.e., messages, …

    Stage

    Not phased

    Ages

    18 and older

    Site

    TSET Health Promotion Research Center, Oklahoma City, Oklahoma

    Run by

    University of Oklahoma

    See if you can join NCT05188287 on ClinicalTrials.gov

17. Bladder Cancer Screening Trial

    There is currently no accepted screening strategy for patients at high risk of developing bladder cancer. This study will ask patients to complete a urine test every 6 months for 2 years to help assess if routine screening helps finding bladder cancer at an earlier stage.

    Stage

    Not phased

    Ages

    50 and older

    Site

    University of Texas Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT05646485 on ClinicalTrials.gov

18. Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

    The purpose of this study is to refine and pilot an intervention using the Nicotine Metabolite Ratio (NMR) to inform the selection of pharmacologic treatment to increase smoking abstinence among Alaska Native and American Indian people. This is a single-arm pilot trial to assess and improve accepta…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Anchorage Native Primary Care Center, Anchorage, Alaska

    Run by

    Southcentral Foundation

    See if you can join NCT06556238 on ClinicalTrials.gov

19. Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

    The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia. The main questions it aims to answer are: * Is QuitAid, alone or combined wi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT05660525 on ClinicalTrials.gov

20. Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

    This study's long-term goal is to improve clinical outcomes among smokers living with HIV (SLWH) by providing smoking cessation interventions in HIV clinical care that will increase the chances of quitting smoking, limits costs and burden on staff and reach many smokers living with HIV.

    Stage

    Phase 4

    Ages

    18 and older

    Site

    New York University School of Global Public Health, New York, New York

    Run by

    New York University

    See if you can join NCT06598397 on ClinicalTrials.gov

21. Quitxt Mobile Text Messaging Cessation Research Study

    The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke. The goal of the proposed study is to evaluate the effectiveness of the bilingual and culturally tailored Quitxt mobile ces…

    Stage

    Not phased

    Ages

    18 to 29

    Site

    The University of Texas Health Science Center at San Antonio, San Antonio, Texas

    Run by

    The University of Texas Health Science Center at San Antonio

    See if you can join NCT05958667 on ClinicalTrials.gov

22. ACT Lung Health Intervention: Phase Two

    This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Dana-Farber Cancer Institute, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT06945120 on ClinicalTrials.gov

23. Enhancing Smoking Cessation Via Telehealth Options in Primary Care

    The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking about smoking history, motivation to …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT05493254 on ClinicalTrials.gov

24. Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

    The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation across rural primary care settings. Participants will be randomly assigned to receive either the smoking cessation e-visit or not. The e-visit will look similar to an online questionnaire asking ab…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT05764759 on ClinicalTrials.gov

25. Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment

    This study will evaluate the efficacy of extended bupropion(6 months) versus standard bupropion treatment (7 weeks) among African American daily smokers.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Missouri

    Run by

    University of Kansas Medical Center

    See if you can join NCT05732272 on ClinicalTrials.gov