Sleep Clinical Trials

76 studies are recruiting for sleep in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. The Effects of a Nutritional Supplement on Sleep Quality

   This study is a randomized, double-blind, placebo-controlled study of N=140 adult men and women with sub-clinical sleep issues. This study to assess the effect of a novel dietary supplement on sleep related outcomes.

   Stage

   Not phased

   Ages

   35 to 65

   Site

   Citruslabs, Santa Monica, California

   Run by

   Athletic Greens International

   See if you can join NCT07345260 on ClinicalTrials.gov

2. Nighttime Synchrony of Your Nutrition and Circadian Health

   Sleep is an important factor for overall health. This study will see how different light exposure patterns and food intake impact a person's metabolism (how the body breaks down food) when sleeping is reduced. Participants will attend 6 to 8 in-person visits to the study clinic, including three ove…

   Stage

   Not phased

   Ages

   18 to 35

   Site

   College of Health Research Complex - University of Utah, Salt Lake City 84112, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT07329283 on ClinicalTrials.gov

3. Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)

   Ketones are molecules generated by the body during the metabolism of fat. Exogenous ketones (EK) are substances that can raise the level of ketones in the circulation without changing diet. In this research study, the investigators are testing the tolerability, sleep effects, and dose effects of a …

   Stage

   Phase 1

   Ages

   18 to 50

   Site

   Johns Hopkins Bayview, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT07224074 on ClinicalTrials.gov

4. The Effects on Sleep Quality of 1:4 Reishi Liquid Extract

   Examining the effects of 1ml of Reishi mushroom extract (1:4 extraction ratio, two hot water extractions and an alcohol extraction), taken daily, 30 mins before bed on perceived sleep quality and stress levels. Sleep quality includes: duration, sleep onset latency, nighttime wakings, and perceived …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Efforia, New York, New York

   Run by

   Efforia, Inc

   See if you can join NCT07294482 on ClinicalTrials.gov

5. Chilipad Sleep Optimization Study

   This study evaluates the Chilipad Dock Pro Bed Cooling System and Sleep Tracker, examining how bed temperature influences sleep quality and overall well-being.

   Stage

   Not phased

   Ages

   Any age

   Site

   Efforia, New York, New York

   Run by

   Efforia, Inc

   See if you can join NCT07281963 on ClinicalTrials.gov

6. Evaluating SleepWhale Drops for Rest & Resilience

   30-day study evaluating SleepWhale Natural Sleep Drops (Extra Strength)-formulated to support deeper sleep and better days.

   Stage

   Not phased

   Ages

   Any age

   Site

   Efforia, New York, New York

   Run by

   Efforia, Inc

   See if you can join NCT07298161 on ClinicalTrials.gov

7. The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

   The overall purpose of this study is to understand the role of disrupted sleep in the association of exposure to early life adversity (adverse childhood experiences (ACEs)) with vascular endothelial (dys)function. In Aim 1 (The Iowa ACEs and Sleep Cohort Study), the investigators will utilize a cro…

   Stage

   Not phased

   Ages

   18 to 29

   Site

   Integrative Laboratory of Applied Physiology and Lifestyle Medicine, Iowa City, Iowa

   Run by

   Nathaniel Jenkins

   See if you can join NCT06454344 on ClinicalTrials.gov

8. A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

   The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main que…

   Stage

   Not phased

   Ages

   3 to 4

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT06667661 on ClinicalTrials.gov

9. Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

   To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this st…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   MD Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT05474846 on ClinicalTrials.gov

10. COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise

    The purpose of this study is to find out whether the COVID pandemic has affected participants' current physical activity, fitness, blood pressure, sleep, and mental stress to better understand its long-term health effects. To complete this study, participants will visit the Neurovascular Physiology…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Indiana University School of Public Health, Bloomington, Indiana

    Run by

    Indiana University

    See if you can join NCT07128095 on ClinicalTrials.gov

11. The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)

    Opioid use disorder (OUD) is a chronic relapsing disorder and is well-known for its high-risk rate of overdoses and death. In OUD, sleep and circadian disruptions are highly prevalent, interfere with opioid maintenance treatment outcomes and increase the risk of relapse. So far, commonly used pharm…

    Stage

    Not phased

    Ages

    18 to 60

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT06832007 on ClinicalTrials.gov

12. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

    Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06055036 on ClinicalTrials.gov

13. Wellness Intervention for Smoking and HIV

    The investigators propose to use a parallel group, randomized controlled trial to test the efficacy of a 13-week personalized approach to reducing smoking intervention versus a second approach using a different health intervention on smoking cessation, healthy sleep metrics, and biomarkers of cardi…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Banner University Medical Center Phoenix, Phoenix, Arizona

    Locations

    2 in total

    Run by

    University of Arizona

    See if you can join NCT04725617 on ClinicalTrials.gov

14. Cannabis for Palliative Care in Cancer

    Many cancer patients suffer from pain, sleep, and mood problems and are using cannabis to relieve these symptoms. Cannabis may provide such relief but may also produce negative side effects including cognitive impairment, an especially problematic issue for cancer patients, indicating more research…

    Stage

    Phase 2

    Ages

    25 and older

    Site

    Anschutz Health Sciences Building, Aurora, Colorado

    Run by

    University of Colorado, Boulder

    See if you can join NCT06266611 on ClinicalTrials.gov

15. Apple Health Study

    The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information collected from apps and devices relate to health and may be used to predict, detect, monitor, and manage changes in health. To enroll, US r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    MCRA, Washington D.C., District of Columbia

    Locations

    2 in total

    Run by

    Apple Inc.

    See if you can join NCT06958523 on ClinicalTrials.gov

16. Shifting Sleep Timing in Teens

    The goal of this clinical trial is to determine whether a combination of a novel lighting intervention and a behavioral intervention are able to increase total sleep time in adolescents. The main questions this trial aims to answer are whether this combination therapy is able to meaningfully increa…

    Stage

    Not phased

    Ages

    14 to 18

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT05808179 on ClinicalTrials.gov

17. Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

    The aim of this study is to design a sleep and mindfulness intervention to improve sleep, quality of life, and cognitive function among older adults.

    Stage

    Not phased

    Ages

    55 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06989619 on ClinicalTrials.gov

18. Sleep-dependent Learning in Aging

    The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory pro…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University of Massachusetts, Amherst, Massachusetts

    Run by

    University of Massachusetts, Amherst

    See if you can join NCT03840083 on ClinicalTrials.gov

19. The Sweet Dreams Study - Accuracy of Sleep Trackers in Children

    The study aims to evaluate the accuracy of sleep trackers in children aged 2 to less than 18 years. Children undergoing polysomnography, the gold standard for assessing sleep quality and duration, at Arkansas Children's Hospital may be eligible to participate. Participants will be asked to wear sle…

    Stage

    Not phased

    Ages

    2 to 17

    Site

    Arkansas Children's Hospital, Little Rock, Arkansas

    Locations

    2 in total

    Run by

    Arkansas Children's Hospital Research Institute

    See if you can join NCT06787378 on ClinicalTrials.gov

20. My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes

    The proposed research and training will allow Dr. Alana Biggers to obtain critical research skills and study a mindfulness meditation program designed to improve sleep and reduce stress in African-American adults with diabetes. If effective, this program may reduce the risk of cardiovascular diseas…

    Stage

    Not phased

    Ages

    21 to 75

    Site

    University of Illinois at Chicago, Chicago, Illinois

    Run by

    University of Illinois at Chicago

    See if you can join NCT05208164 on ClinicalTrials.gov

21. Home Sleep Therapy for Older Adults With MCI

    The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in people with mild cognitive impairment via home use sleep therapy device (SleepWISP) as well as learn about biomarkers as…

    Stage

    Not phased

    Ages

    40 to 85

    Site

    Brain Electrophysiology Laboratory Company, Eugene, Oregon

    Locations

    2 in total

    Run by

    Brain Electrophysiology Laboratory Company

    See if you can join NCT05771844 on ClinicalTrials.gov

22. Lemborexant Treatment of Insomnia Linked to Epilepsy

    The goal of this clinical trial is to assess whether Lemborexant can improve sleep in patients with epilepsy.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Health Sciences Centre, Winnipeg, Manitoba

    Locations

    2 in total

    Run by

    University of Manitoba

    See if you can join NCT06262594 on ClinicalTrials.gov

23. The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

    Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children. In this study the investigators will adapt, refine, and pilot test the implementation of…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Rhode Island Hospital, Providence, Rhode Island

    Run by

    Rhode Island Hospital

    See if you can join NCT06737055 on ClinicalTrials.gov

24. Student Exercise and Sleep Timing Study - Part 2

    The purpose of this study is to examine the effects of a morning exercise intervention on sleep (quality and duration), mood (positive affect, anxiety, depression, anger), stress and productivity among undergraduate students (18-23 years) evening-exercisers with poor self-reported sleep quality. Ai…

    Stage

    Not phased

    Ages

    18 to 23

    Site

    College Avenue Gym, New Brunswick, New Jersey

    Locations

    6 in total

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT06336590 on ClinicalTrials.gov

25. Research Framework Exploring Sleep Health

    This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers. We are also collecting survey/questionnaire data on baseline health and sleep characteristics as well as bi-weekly assessments of sleep quality and mood. Overall, we…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Scripps Research Institute, La Jolla, California

    Run by

    Scripps Translational Science Institute

    See if you can join NCT05197738 on ClinicalTrials.gov