Sleep Clinical Trials

76 studies are recruiting for sleep in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

   The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep difficulties are a promising target for youth with suicidal thoughts and behavior to focus on as a prev…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   2 in total

   Run by

   University of Pittsburgh

   See if you can join NCT06963463 on ClinicalTrials.gov

2. SCREENS: Sleep, Circadian Rhythms, and Electronics in the EveNing Study

   The proposed project aims to disentangle the impact of evening light exposure emitted from tablet devices from the impact of arousing media content on children's sleep regulation, circadian physiology and next-day emotion regulation and executive functioning.

   Stage

   Not phased

   Ages

   8 to 11

   Site

   Children's Nutrition Research Center, Houston, Texas

   Run by

   Baylor College of Medicine

   See if you can join NCT06192745 on ClinicalTrials.gov

3. Sleep and Performance

   This research is being done to apply new, contrast-free MRI (Magnetic Resonance Imaging) methods to understand the brain's waste clearance system (the "glymphatic" system) in younger adults. The Investigators hope the study will show how the different brain regions are involved in maintaining memor…

   Stage

   Not phased

   Ages

   18 to 30

   Site

   University of Washington School of Medicine, Seattle, Washington

   Run by

   University of Washington

   See if you can join NCT07608614 on ClinicalTrials.gov

4. Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

   The goal of this clinical trial is to conduct a comparative effectiveness trial that will evaluate two school-based interventions to improve adolescent sleep health: the standard Sleep Health Education (SHE) and a stepped care version of the Transdiagnostic Sleep and Circadian intervention (TS-C-ST…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Locations

   2 in total

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT07213908 on ClinicalTrials.gov

5. Light Therapy to Improve Sleep in TBI: Sleep-active Biomarkers and Glymphatic Function

   This is a clinical trial designed to examine how improved sleep through morning bright light therapy is improving downstream key physiologic processes related to brain health, i.e., mitochondrial function, systemic inflammation, and glymphatic function. All proposed methodology is already approved …

   Stage

   Not phased

   Ages

   18 to 89

   Site

   Oregon Health and Science University, Portland, Oregon

   Run by

   Oregon Health and Science University

   See if you can join NCT07601841 on ClinicalTrials.gov

6. The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU

   The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT04737200 on ClinicalTrials.gov

7. Assessing Improvements in Mood and Sleep Trial

   This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things …

   Stage

   Not phased

   Ages

   55 and older

   Site

   The Regents of the University of California, Los Angeles, Los Angeles, California

   Locations

   3 in total

   Run by

   University of Pittsburgh

   See if you can join NCT06639477 on ClinicalTrials.gov

8. Sleep Behaviors in Pregnancy

   The researchers would like to know how long pregnant women spend in different positions during the night - and how often women change positions - across pregnancy. The researchers also want to see if the sleep monitor is able to improve sleep behaviors

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT04205370 on ClinicalTrials.gov

9. The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

   The investigators are interested in finding out how Prolonged Nightly Fasting (PNF) and/or health education may impact health and cancer recovery for breast cancer patients and survivors.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Arizona State University, Phoenix, Arizona

   Run by

   Arizona State University

   See if you can join NCT06938555 on ClinicalTrials.gov

10. Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

    This study will employ cognitive behavioral therapy for insomnia (CBT-I) among individuals with mild traumatic brain injury (mTBI) who experience sleep disturbances. The research aims to evaluate the effects of CBT-I on sleep, mTBI symptoms, and, in particular, the ability of individuals with mTBI …

    Stage

    Not phased

    Ages

    18 to 60

    Site

    University of Missouri-Columbia, Columbia, Missouri

    Run by

    University of Missouri-Columbia

    See if you can join NCT07385105 on ClinicalTrials.gov

11. Light Exposure, Migraine Outcomes, and Sleep Quality

    The purpose of this study is to examine the relationship between daily light exposure patterns, sleep quality, and migraine characteristics in adults with migraine, with and without photophobia, across an 8-week study period.

    Stage

    Not phased

    Ages

    18 and older

    Site

    ASU DeSmart Lab, Tempe, Arizona

    Run by

    Arizona State University

    See if you can join NCT07476053 on ClinicalTrials.gov

12. Sleep Health in U.S. Marines

    The goal of this study is to test a sleep health program designed specifically for U.S. Marine Corps personnel. Researchers want to determine if this program helps Marines improve the participants sleep quality and overall mental health. The study will evaluate whether the program improves sleep qu…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    San Diego State University, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT07420205 on ClinicalTrials.gov

13. The Effect of Sleep Loss on Emotion Regulation

    The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights …

    Stage

    Not phased

    Ages

    18 to 40

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT05393830 on ClinicalTrials.gov

14. Validation of Presence-IP1.0 for Detection of Consciousness Using Reduced-Montage TMS-EEG

    This study aims to validate a novel real-time algorithm (Presence-IP1.0) designed to detect consciousness from TMS-evoked EEG responses using a reduced electrode montage. Thirty healthy adult participants will undergo TMS-EEG recordings during wakefulness and sleep. The algorithm's ability to diffe…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    UW School of Medicine and Public Health, Madison, Wisconsin

    Run by

    University of Wisconsin, Madison

    See if you can join NCT07523191 on ClinicalTrials.gov

15. Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents

    Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times, which may incre…

    Stage

    Not phased

    Ages

    13 to 18

    Site

    Western Psychiatric Hospital, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT05336084 on ClinicalTrials.gov

16. Effect of Early Parent Education on Children's Sleep

    The goal of this clinical trial is to learn if providing sleep information and advice to expecting parents can increase sleep duration and decrease sleep problems in infants. The main questions it aims to answer is: * Does providing sleep information and advice to parents after birth enhance baby's…

    Stage

    Not phased

    Ages

    Any age

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT07515534 on ClinicalTrials.gov

17. Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

    The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1. Does cannabis use and discontinuation impact sleep drive? 2. Does cannabis use and discontinuation impact light sensitivity…

    Stage

    Not phased

    Ages

    18 to 25

    Site

    Western Psychiatric Hospital (Thomas Detre Hall), Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT06743373 on ClinicalTrials.gov

18. Repurposing Low-Dose Clonidine for PTSD in Veterans

    Hypothesis: Veterans with PTSD prescribed clonidine will demonstrate improvements in PTSD symptoms, including daytime, nighttime, and sleep-related behaviors.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Aurora Psychiatric Hospital, Wauwatosa, Wisconsin

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT04877093 on ClinicalTrials.gov

19. The Use of Multiple Sensors to Track Sleep in Nightshift Workers

    Sleep is often a challenge for nightshift workers because their work and sleep schedules are inverted. Sleep is commonly measured using actigraphy, which is the standard measure of objective sleep in the general population; however, this method has substantial limitations for nightshift workers bec…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Henry Ford Columbus Medical Center, Novi, Michigan

    Run by

    Henry Ford Health System

    See if you can join NCT06670287 on ClinicalTrials.gov

20. MyVitalC: Sleep and Everyday Headache Management

    Sleep disturbance and recurring headaches can negatively affect daily functioning, mood, and productivity. MyVitalC (ESS60 in extra virgin olive oil) is a commercially available dietary supplement that has generated anecdotal claims related to sleep quality and headache relief; however, human data …

    Stage

    Not phased

    Ages

    Any age

    Site

    Efforia, New York, New York

    Run by

    Efforia, Inc

    See if you can join NCT07477236 on ClinicalTrials.gov

21. Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

    To date, there are very few established sleep health education models targeting caregivers of school-aged children from historically marginalized and/or low income communities. To address this significant gap, this project seeks to examine the feasibility, acceptability, and usability of the Bedtim…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT06618040 on ClinicalTrials.gov

22. Sleep and Physical Activity in Patient and Caregiver Dyads Following Allogeneic Hematopoietic Cell Transplantation

    To understand the changes in health-related quality of life of patients and caregivers after allogeneic hematopoietic cell transplantation.

    Stage

    Not phased

    Ages

    18 and older

    Site

    MD Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT07140770 on ClinicalTrials.gov

23. Examination of the Dynamic Relationships of Sleep, Physical Activity, and Circadian Rhythmicity With Neurobehavioral Heterogeneity in ADHD

    Attention deficit/hyperactivity disorder (ADHD) can present differently in individuals, with some individuals having difficulty with attentional control, hyperactivity, impulsivity, emotion dysregulation, and/or neurobehavioral functioning. The factors contributing to these different presentations …

    Stage

    Not phased

    Ages

    8 to 12

    Site

    Hugo W. Moser Research Institute at Kennedy Krieger, Baltimore, Maryland

    Locations

    2 in total

    Run by

    Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

    See if you can join NCT06810180 on ClinicalTrials.gov

24. Sleep and Circadian Mechanisms in Hypertension

    This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).

    Stage

    Not phased

    Ages

    25 to 64

    Site

    Oregon Health and Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT05184933 on ClinicalTrials.gov

25. Sleep and Morning Wellbeing Study

    The study will be a prospective randomized, controlled clinical study. There will be interventional treatment for a total of 30 days. The subjects will complete questionnaires throughout the study at pre-specified timepoints.

    Stage

    Not phased

    Ages

    22 to 59

    Site

    Alethios (Virtual Study Platform), San Francisco, California

    Run by

    Athletic Greens International

    See if you can join NCT07311434 on ClinicalTrials.gov