Rheumatoid Arthritis Clinical Trials in Houston, Texas

8 studies are recruiting for rheumatoid arthritis in Houston, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

   The study will evaluate the long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with moderate to severe Rheumatoid Arthritis (RA) who have an inadequate response or intolerance to tumor necrosis factor (TNF) and/or Janus kinase (JAK) inhibitors, and who were previo…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Accurate Clinical Management LLC, Houston, Texas

   Locations

   10 in total

   Run by

   Hoffmann-La Roche

   See if you can join NCT07620392 on ClinicalTrials.gov

2. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

   This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   UT MD Anderson Cancer Center, Houston, Texas

   Locations

   52 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT03816345 on ClinicalTrials.gov

3. A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

   This study will assess the efficacy and safety of Afimkibart (also known as RO7790121) compared with placebo in participants with moderate to severe rheumatoid arthritis (RA) who have an inadequate response or intolerance to TNF and/or JAK inhibitors.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Accurate Clinical Management, Houston, Texas

   Locations

   63 in total

   Run by

   Hoffmann-La Roche

   See if you can join NCT07137598 on ClinicalTrials.gov

4. A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

   This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Nkarta Investigational Site, Houston, Texas

   Locations

   18 in total

   Run by

   Nkarta, Inc.

   See if you can join NCT06733935 on ClinicalTrials.gov

5. RA-PRO PRAGMATIC TRIAL

   The 2021 ACR RA treatment guideline, based on widely acknowledged low to moderate quality evidence, recommends switching to a non-tumor necrosis factor (TNFi) biologic (choose among existing medications, currently, rituximab, abatacept, tocilizumab, or sarilumab) or a targeted synthetic DMARD arm (…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Baylor University, Houston, Texas

   Locations

   49 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04692493 on ClinicalTrials.gov

6. A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

   Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. This study will evaluate the efficacy and safety of targeted therapies through a series of substudies for the treatment of moderately to severely active Rheumatoid Arthritis (RA…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Accurate Clinical Research - Houston /ID# 272271, Houston, Texas

   Locations

   104 in total

   Run by

   AbbVie

   See if you can join NCT06972446 on ClinicalTrials.gov

7. A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

   Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Research Site, Houston, Texas

   Locations

   144 in total

   Run by

   AstraZeneca

   See if you can join NCT07276581 on ClinicalTrials.gov

8. Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

   This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibility, and content of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT04751396 on ClinicalTrials.gov