Posttraumatic Stress Disorder Clinical Trials

38 studies are recruiting for posttraumatic stress disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry

   Objective: Posttraumatic stress disorder (PTSD) is a prevalent neuropsychiatric disorder in children and is associated with increased neurovascular inflammation, suicidality, adulthood mental health disorder, and major adverse events. Reminder focused positive psychiatry (RFPP) has been shown as we…

   Stage

   Not phased

   Ages

   11 to 15

   Site

   UCLA, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT04529031 on ClinicalTrials.gov

2. Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

   Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improving outcomes and providing Veteran-centered care, and surveys of Veterans in outpatient VA PTSD care …

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Locations

   3 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT05267665 on ClinicalTrials.gov

3. CIH Stepped Care for Co-occurring Chronic Pain and PTSD

   The goal of this clinical trial is to evaluate the feasibility, acceptability, appropriateness, and retention of patient participants of a CIH Stepped Care approach for co-occurring chronic pain and PTSD vs. treatment as usual in two primary care settings (one rural and one urban). Researchers will…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Washington, Seattle, Washington

   Run by

   University of Washington

   See if you can join NCT06219408 on ClinicalTrials.gov

4. Written Exposure Therapy for Veterans With SUD and PTSD

   The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD). While SUD treatment programs traditionally do not address PTSD, effective trauma tr…

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut

   Run by

   VA Office of Research and Development

   See if you can join NCT05327504 on ClinicalTrials.gov

5. Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

   The goal of this clinical trial is to compare two different intensive formats of delivering cognitive-behavioral treatment for people with PTSD and anxiety disorders. The main questions it aims to answer are: * Is iTCBT delivered in individual and group formats more effective than TAU in improving …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Michael E. DeBakey VA Medical Center, Houston, Texas

   Run by

   Baylor College of Medicine

   See if you can join NCT05843695 on ClinicalTrials.gov

6. Mitigating PTSD-CUD After Sexual Assault

   683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD). The current proposal will test the acceptability, initial efficacy, and mechanisms underlying …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Harbor Shelter, Smithfield, North Carolina

   Locations

   6 in total

   Run by

   University of Nevada, Las Vegas

   See if you can join NCT05989841 on ClinicalTrials.gov

7. Evaluation of the PE Coach Mobile Application Among Veterans With PTSD

   Thousands of mental health mobile applications (apps) are available but limited research has been conducted on their effectiveness. VA has been a leader in mental health mobile app development and must research whether these apps work, and if so, how? PE Coach is a well-designed treatment companion…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington

   Run by

   VA Office of Research and Development

   See if you can join NCT04959695 on ClinicalTrials.gov

8. Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

   Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members. This research hopes to learn about the effects of art therapy on emotional expre…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   National Intrepid Center of Excellence, Bethesda, Maryland

   Locations

   2 in total

   Run by

   Walter Reed National Military Medical Center

   See if you can join NCT05414708 on ClinicalTrials.gov

9. Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

   By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly that might improve treatment response. The investigators also want to l…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Augusta VA, Augusta, Georgia

   Locations

   4 in total

   Run by

   The University of Texas Health Science Center at San Antonio

   See if you can join NCT07176273 on ClinicalTrials.gov

10. A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation

    This study will be the first of its kind to explore the impact of continuous theta burst stimulation (cTBS) to the intraparietal sulcus (IPS) on arousal symptoms among patients with posttraumatic stress disorder (PTSD). The investigators will demonstrate that IPS cTBS results in significant reducti…

    Stage

    Not phased

    Ages

    18 to 60

    Site

    Center for the Treatment and Study of Anxiety, University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT06234969 on ClinicalTrials.gov

11. Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

    Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Texas at Austin, Austin, Texas

    Run by

    University of Texas at Austin

    See if you can join NCT05427708 on ClinicalTrials.gov

12. Mechanisms Underlying the Efficacy of Prolonged Exposure

    The primary objective of this research is to collect pilot data that demonstrates that proposed neural, psychophysiological and subjective markers measured before, during, and after treatment change over the course of Prolonged Exposure therapy (PE) for posttraumatic stress disorder (PTSD). The aim…

    Stage

    Not phased

    Ages

    18 to 90

    Site

    VA Boston Healthcare System, Boston, Massachusetts

    Run by

    VA Boston Healthcare System

    See if you can join NCT05663151 on ClinicalTrials.gov

13. Biomarkers in the Retina for Prognosticating Mental Health Treatments

    Title: ERG as a potential biomarker of SSRI-responsive PTSD: A pilot study Posttraumatic stress disorder (PTSD) affects many individuals who experience a traumatic event. Previous studies suggest that there is a connection between the brain and the retina, and that the electroretinogram (ERG) may b…

    Stage

    Not phased

    Ages

    21 to 75

    Site

    VA Puget Sound Health Care System, Seattle, Washington

    Run by

    VA Puget Sound Health Care System

    See if you can join NCT06363968 on ClinicalTrials.gov