Peripheral Arterial Disease Clinical Trials

35 studies are recruiting for peripheral arterial disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Pounce™ Thrombectomy System Retrospective Registry

   The PROWL registry is an open-label retrospective, multi-center, US study of the Surmodics™ Pounce™ Thrombectomy System for the non-surgical removal of emboli and thrombi in the peripheral arterial vasculature.

   Stage

   Not phased

   Ages

   18 and older

   Site

   OSF St. Francis Medical Center, Peoria, Illinois

   Locations

   9 in total

   Run by

   SurModics, Inc.

   See if you can join NCT05868161 on ClinicalTrials.gov

2. A Real-World Registry of Chronic Wounds and Ulcers

   WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers. Data are collected during routine care from over 1,400 clinicians across the USA and Puerto Rico using a highly structured c…

   Stage

   Not phased

   Ages

   Any age

   Site

   US Wound Registry, The Woodlands, Texas

   Run by

   U.S. Wound Registry

   See if you can join NCT02280733 on ClinicalTrials.gov

3. The ROAMM-EHR Study

   In recent years, mobile health (mHealth) apps have promised improved monitoring of health conditions to improve clinical outcomes. The objective of this study is to conduct a pilot randomized clinical trial (RCT) to evaluate the impact of using remotely collected patient generated health data (PGHD…

   Stage

   Not phased

   Ages

   60 to 100

   Site

   Institute of Aging, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06263322 on ClinicalTrials.gov

4. Effects of Carnosine In Patients With Peripheral Arterial Disease Patients

   The purpose of this study is to determine whether carnosine (a food ingredient found in chicken and red meat) supplementation (2 g) for 6 months in participants with non-claudication and claudication peripheral arterial disease (PAD) improves walking ability. Previous studies with heart failure pat…

   Stage

   Phase 1

   Ages

   40 to 80

   Site

   University of Louisville School of Medicine, Department of Medicine, Division of Environmental Medicine, Louisville, Kentucky

   Locations

   3 in total

   Run by

   Shahid Baba

   See if you can join NCT06480760 on ClinicalTrials.gov

5. Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis

   Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities. The most common clinical manifestation of PAD is claudication, i.e., a severe functional limitation identified as gait dysfunction…

   Stage

   Phase 4

   Ages

   18 to 90

   Site

   VA Medical Center, Omaha, Nebraska

   Run by

   University of Nebraska

   See if you can join NCT02842424 on ClinicalTrials.gov

6. Passive Stretching in Peripheral Arterial Disease Patients

   Peripheral artery disease (PAD) leads to higher mortality rates and strains healthcare systems due to increased costs. It causes leg pain during walking due to reduced blood flow. Nitric oxide (NO) deficiency contributes to vascular issues in PAD, with few effective treatments available. Passive ca…

   Stage

   Phase 2

   Ages

   40 to 90

   Site

   University of Wisconsin La Crosse, La Crosse, Wisconsin

   Run by

   University of Wisconsin, La Crosse

   See if you can join NCT06420752 on ClinicalTrials.gov

7. Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment

   The objective of this trial is to determine if Near-infrared spectroscopy (NIRS) can accurately evaluate the degree of Peripheral Arterial Disease (PAD) during a Provocative Elevation Maneuver of the Lower Extremity (PEMLE) test, as compared to routine clinical assessments.

   Stage

   Not phased

   Ages

   35 to 99

   Site

   University of Texas Health Science Center at San Antonio, San Antonio, Texas

   Run by

   Kent Imaging Inc

   See if you can join NCT06237621 on ClinicalTrials.gov

8. Prehabilitation and Rehabilitation in PAD

   To determine the effectiveness of pre and post-operative exercise therapy in patients undergoing peripheral artery stenting for peripheral arterial disease.

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA Palo Alto Health Care System, Palo Alto, California

   Run by

   Palo Alto Veterans Institute for Research

   See if you can join NCT06566976 on ClinicalTrials.gov

9. Ultrasound Cavitation Therapy for CLI

   In this study, we will explore how ultrasound exposure of ultrasound contrast agents, which produces beneficial shear-mediated bioeffects, can be used to treat patients with severe non-healing ulcers secondary to peripheral arterial disease (PAD). The primary outcome measure is whether ultrasound e…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Virginia, Charlottesville, Virginia

   Run by

   University of Virginia

   See if you can join NCT05749250 on ClinicalTrials.gov

10. Augmentation of Limb Perfusion With Contrast Ultrasound

    Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion. These observations have been made in mice with and without peripheral artery disease (PAD), and also in humans where high power cont…

    Stage

    Not phased

    Ages

    19 to 99

    Site

    OHSU, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT03195556 on ClinicalTrials.gov