Pediatric Cancer Clinical Trials in Philadelphia, Pennsylvania

7 studies are recruiting for pediatric cancer in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Lurbinectedin in FET-Fused Tumors

   The purpose of this study is to find out if a drug called lurbinectedin (the "study drug") is safe and effective at treating people with recurrent or relapsed solid tumors, including Ewing sarcoma.

   Stage

   Phase 1

   Ages

   10 and older

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   6 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05918640 on ClinicalTrials.gov

2. Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

   This study will evaluate BCB-276, an investigational B7-H3-targeted Chimeric Antigen Receptor (CAR) T cell therapy, in children and young adults with diffuse intrinsic pontine glioma (DIPG). DIPG is a rare and aggressive brain tumor with limited treatment options. CAR T cell therapy uses a patient'…

   Stage

   Phase 2

   Ages

   1 to 26

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   6 in total

   Run by

   BrainChild Bio, Inc

   See if you can join NCT07680439 on ClinicalTrials.gov

3. Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

   Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

   Stage

   Phase 2

   Ages

   2 to 25

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   5 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT06458036 on ClinicalTrials.gov

4. Massage Impact on Sleep in Pediatric Oncology

   This study aims to determine the impact of massage therapy for pediatric patients receiving intensive chemotherapy or stem cell transplant (SCT).

   Stage

   Not phased

   Ages

   12 to 21

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   2 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT06892158 on ClinicalTrials.gov

5. Targeted Therapy to Increase RAI Uptake in Metastatic DTC

   Papillary thyroid cancer (PTC) is a common type of differentiated thyroid cancer (DTC) in children and represents the second most common cancer in adolescent females. Recently targeted drugs that block many of the genetic drivers of DTC have become available. While Investigators know that these dru…

   Stage

   Not phased

   Ages

   0 and older

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   9 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05024929 on ClinicalTrials.gov

6. Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

   Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve…

   Stage

   Phase 2

   Ages

   2 to 99

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   5 in total

   Run by

   Children's Hospital of Philadelphia

   See if you can join NCT05783323 on ClinicalTrials.gov

7. Childhood Cancer Predisposition Study (CCPS)

   The Childhood Cancer Predisposition Study (CCPS) is a multi-center, longitudinal, observational study that will collect clinical and biological data and specimens from children with a cancer predisposition syndromes (CPS) and their relatives. The central hypothesis is that studying individuals at h…

   Stage

   Not phased

   Ages

   Any age

   Site

   Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

   Locations

   7 in total

   Run by

   Emory University

   See if you can join NCT04511806 on ClinicalTrials.gov