Parkinson Disease Clinical Trials in Philadelphia, Pennsylvania

6 studies are recruiting for parkinson disease in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

   The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic p…

   Stage

   Phase 2

   Ages

   40 to 80

   Site

   Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

   Locations

   72 in total

   Run by

   Neuron23 Inc.

   See if you can join NCT06680830 on ClinicalTrials.gov

2. Using the EHR to Advance Genomic Medicine Across a Diverse Health System

   Given the expansion of indications for genetic testing and our understanding of conditions for which the results change medical management, it is imperative to consider novel ways to deliver care beyond the traditional genetic counseling visit, which are both amenable to large-scale implementation …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Penn Medicine, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06377033 on ClinicalTrials.gov

3. PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

   The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest…

   Stage

   Not phased

   Ages

   30 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   50 in total

   Run by

   Michael J. Fox Foundation for Parkinson's Research

   See if you can join NCT04477785 on ClinicalTrials.gov

4. A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

   The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered to the putamen in subjects with moderate Parkinson's Disease.

   Stage

   Phase 2

   Ages

   45 to 75

   Site

   University of Pennsylvania (Neurology), Philadelphia, Pennsylvania

   Locations

   46 in total

   Run by

   AskBio Inc

   See if you can join NCT06285643 on ClinicalTrials.gov

5. Abbott DBS Post-Market Study of Outcomes for Indications Over Time

   The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.

   Stage

   Not phased

   Ages

   Any age

   Site

   Thomas Jefferson Department or Neurosurgery, Philadelphia, Pennsylvania

   Locations

   48 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT04071847 on ClinicalTrials.gov

6. Parkinson's Disease and Movement Disorders Clinical Database

   The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and brain images of patients with Parkinson's disease and related disorders receiving care at the Parki…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT04997642 on ClinicalTrials.gov