Parkinson Disease Clinical Trials in Minneapolis, Minnesota

8 studies are recruiting for parkinson disease in Minneapolis, Minnesota right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Pathways Mediating Impaired Postural Control in Parkinson's Disease

   The purpose of this project is to use transcranial magnetic stimulation (TMS) to explore the state of excitability of corticocortical and corticofugal (cortex to spinal cord, cortex to brainstem to spinal cord) pathways that project to muscles that control the legs and trunk in people with Parkinso…

   Stage

   Not phased

   Ages

   45 to 80

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06464029 on ClinicalTrials.gov

2. Imaging Core Aim 2, and Udall Project 2 Aim 2

   More than one million people in the United States have Parkinson's disease (PD) and the prevalence is expected to double by 2040. Over 60% of these individuals will develop debilitating postural instability and gait disturbances (PIGD), including freezing of gait (FOG). With disease progression, ax…

   Stage

   Not phased

   Ages

   21 and older

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06998303 on ClinicalTrials.gov

3. Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder

   Sixty patients will be enrolled in this study who are treated for Parkinson's disease (PD) with bilateral deep brain stimulation of subthalamic nucleus (STN) or globus pallidus (GP), who have a pre- operative 7 Tesla MRI including diffusion tensor imaging for tractography and a postoperative head C…

   Stage

   EARLY_Phase 1

   Ages

   18 to 89

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT05893186 on ClinicalTrials.gov

4. Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease

   Currently, there is a lack of comprehensive knowledge about the role of vestibulospinal drive and cortical activity during self-initiated movement transitions in older adults and people with PD (both with and without FOG). This set of experiments has two primary purposes: to (1) understand the path…

   Stage

   Not phased

   Ages

   21 to 80

   Site

   University of Minnesota, Movement Disorders Lab, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06506058 on ClinicalTrials.gov

5. Characterizing the Pathophysiological Role of the Pallido-thalamocortical Motor Pathway in Parkinson's Disease.

   When a patient gets DBS surgery, the neurosurgeon makes a hole in the skull through which they can put the DBS lead down in deep parts of the brain that help control movement. For this study, research participants will also have an ECoG strip put through the same hole (no extra holes are being made…

   Stage

   Not phased

   Ages

   21 to 75

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06692920 on ClinicalTrials.gov

6. Udall Project 2 Aim 2A&C

   This protocol will leverage the novel (on-label, FDA-approved) local field potential measuring capability of the Medtronic Percept™ PC or RC DBS system to study the effects of globus pallidus internus, globus pallidus externus (GPi, GPe), and subthalamic nucleus (STN) DBS on: the wash-out and wash-…

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT05656586 on ClinicalTrials.gov

7. Percept Transitions in FOG and PD

   The purpose of this research is to examine the possible causes and signs of freezing of gait (FOG) secondary to Parkinson's disease (PD). To achieve this, the study will use the novel (on-label and FDA-approved) local field potential (LFP) measuring capability of the Medtronic Percept™ deep brain s…

   Stage

   Not phased

   Ages

   21 to 75

   Site

   University of Minnesota, Movement Disorders Lab, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06848205 on ClinicalTrials.gov

8. Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

   This study will help us better understand how the brain works in people with Parkinson's disease (PD). PD is a brain disease that gets worse over time, and affects over 10 million people world-wide. A common treatment for PD is Deep Brain Stimulation (DBS). To improve DBS therapy for PD, we need a …

   Stage

   Not phased

   Ages

   21 and older

   Site

   University Of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT05658302 on ClinicalTrials.gov