Parkinson Disease Clinical Trials in Cleveland, Ohio

9 studies are recruiting for parkinson disease in Cleveland, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

   This is a Phase 2 study in people with Parkinson's disease who experience motor fluctuations while taking levodopa. The study will evaluate how effective two different doses of the study drug AP-472 are when added to levodopa treatment, compared with a placebo. The study will last about 12 weeks. P…

   Stage

   Phase 2

   Ages

   30 to 80

   Site

   Cleveland Clinic (Site #223), Cleveland, Ohio

   Locations

   30 in total

   Run by

   Appello Pharmaceuticals, Inc.

   See if you can join NCT07432958 on ClinicalTrials.gov

2. Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

   This study employs an exploratory, prospective, single center, naturalistic clinical trial design with a randomized crossover intervention.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT07110376 on ClinicalTrials.gov

3. Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

   The proposed multi-site, Genetics and Aerobic Exercise to Slow PD (GEARS) Trial will, for the first time, determine the interplay between genetics and exercise in altering PD progression. In sum, 200 PD patients will be recruited from the Cleveland and Salt Lake City metro areas to participate in t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Cleveland Clinic, Cleveland, Ohio

   Run by

   Jay Alberts

   See if you can join NCT06442033 on ClinicalTrials.gov

4. Personalized Real-Time DBS and PD Mechanisms

   A prospective cohort of patients scheduled to undergo deep brain stimulation (DBS) implantation surgery for the treatment of Parkinson's disease as per standard of care will be invited to participate in this study. This mechanistic study is aimed at better understanding the role of basal ganglia be…

   Stage

   Phase 4

   Ages

   18 to 80

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   David Escobar

   See if you can join NCT06013956 on ClinicalTrials.gov

5. PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

   The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest…

   Stage

   Not phased

   Ages

   30 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Locations

   50 in total

   Run by

   Michael J. Fox Foundation for Parkinson's Research

   See if you can join NCT04477785 on ClinicalTrials.gov

6. BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

   The purpose of this study is to evaluate the effect of IPX203 (Crexont®) - the newest extended-release levodopa formulation - on the duration and quality of good on time, using a wearable device to monitor symptoms. 'Good on time' refers to a period (minutes to hours) when a patient experiences opt…

   Stage

   Phase 4

   Ages

   40 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT07138560 on ClinicalTrials.gov

7. Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

   BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to tra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University Hospitals Cleveland Medical Center, Cleveland, Ohio

   Locations

   12 in total

   Run by

   Michael J. Fox Foundation for Parkinson's Research

   See if you can join NCT06719583 on ClinicalTrials.gov

8. Abbott DBS Post-Market Study of Outcomes for Indications Over Time

   The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.

   Stage

   Not phased

   Ages

   Any age

   Site

   The Cleveland Clinic Foundation, Cleveland, Ohio

   Locations

   48 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT04071847 on ClinicalTrials.gov

9. A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

   The primary purpose of this study is to evaluate efficacy and safety of CREXONT under real world conditions in participants with Parkinson disease (PD).

   Stage

   Phase 4

   Ages

   18 and older

   Site

   University Hospitals Cleveland Medical Center, Cleveland, Ohio

   Locations

   27 in total

   Run by

   Impax Laboratories, LLC

   See if you can join NCT06765668 on ClinicalTrials.gov