Parkinson Disease Clinical Trials in Ann Arbor, Michigan

7 studies are recruiting for parkinson disease in Ann Arbor, Michigan right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

   This is a Phase 2 study in people with Parkinson's disease who experience motor fluctuations while taking levodopa. The study will evaluate how effective two different doses of the study drug AP-472 are when added to levodopa treatment, compared with a placebo. The study will last about 12 weeks. P…

   Stage

   Phase 2

   Ages

   30 to 80

   Site

   University of Michigan Health System (UMHS) (Site #202), Ann Arbor, Michigan

   Locations

   30 in total

   Run by

   Appello Pharmaceuticals, Inc.

   See if you can join NCT07432958 on ClinicalTrials.gov

2. A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

   This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static st…

   Stage

   Phase 1

   Ages

   50 and older

   Site

   Domino's Farms, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT07543861 on ClinicalTrials.gov

3. PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

   The Parkinson Progression Marker Initiative (PPMI) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest…

   Stage

   Not phased

   Ages

   30 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Locations

   50 in total

   Run by

   Michael J. Fox Foundation for Parkinson's Research

   See if you can join NCT04477785 on ClinicalTrials.gov

4. Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

   This study explores how a specific genetic mutation of leucine-rich repeat kinase 2 (LRRK2) affects individuals with Parkinson's disease (PD), comparing those with the mutation to others with Parkinson's disease and without the mutation (iPD). Participants will complete positron emission tomography…

   Stage

   Not phased

   Ages

   45 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT07642908 on ClinicalTrials.gov

5. Natural History Study of Synucleinopathies

   Synucleinopathies are a group of rare diseases associated with worsening neurological deficits and the abnormal accumulation of the protein α-synuclein in the nervous system. Onset is usually in late adulthood at age 50 or older. Usually, synucleinopathies present clinically with slowness of moveme…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Locations

   8 in total

   Run by

   NYU Langone Health

   See if you can join NCT01799915 on ClinicalTrials.gov

6. Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease

   This trial aims to test whether one year of Varenicline, when compared to placebo, can reduce fall risk and show improvement in the ability to multitask while walking. Participants that are eligible after screening for the study will be randomized to receive Varenicline or placebo. Along with the s…

   Stage

   Phase 2

   Ages

   45 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   Vikas Kotagal

   See if you can join NCT06679374 on ClinicalTrials.gov

7. Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

   The goal of this clinical trial is to learn if taking a tributyrin supplement works to improve memory and thinking and walking and balance in adults with Parkinson disease Parkinson disease dementia. It will also learn about the safety of tributyrin supplementation. The main questions it aims to an…

   Stage

   Phase 1

   Ages

   45 and older

   Site

   Domino's Farms, Ann Arbor, Michigan

   Run by

   Prabesh Kanel

   See if you can join NCT07154511 on ClinicalTrials.gov