Pain, Postoperative Clinical Trials

42 studies are recruiting for pain, postoperative in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.

   This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, sev…

   Stage

   Phase 4

   Ages

   18 to 59

   Site

   Loma Linda University Health, Loma Linda, California

   Run by

   Loma Linda University

   See if you can join NCT04860141 on ClinicalTrials.gov

2. Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

   The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative pain, as measured by visual analog scale (VAS). The amount of pain medica…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Stanford University, Redwood City, California

   Run by

   Stanford University

   See if you can join NCT04109638 on ClinicalTrials.gov

3. VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)

   The goal of this project is to test the effects of the VibraCool mechanical stimulation neuromodulatory therapeutic device on post-operative pain and opioid use following anterior crucitate ligament reconstruction (ACLR), and thus residual opioids in circulation.

   Stage

   Not phased

   Ages

   Any age

   Site

   Columbia University Medical Center, New York, New York

   Run by

   Columbia University

   See if you can join NCT06456268 on ClinicalTrials.gov

4. fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

   Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).

   Stage

   Not phased

   Ages

   8 to 35

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT04439552 on ClinicalTrials.gov

5. Transcutaneous Auricular Neurostimulation After Lumbar Surgery

   The purpose of this study, entitled "Delivering Transcutaneous Auricular Neurostimulation as an Adjunct Non-Opioid Pain Management Therapy for Patients Undergoing Lumbar Surgery", is to demonstrate whether transcutaneous auricular neurostimulation (tAN) can non-invasively reduce the perception of p…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   UT Southwestern Medical Center, Dallas, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT06100172 on ClinicalTrials.gov

6. Continuous Infusions vs Scheduled Bolus Infusions

   The goal of the study is to compare continuous infusions and scheduled bolus infusions for peripheral nerve blocks and their effect on post-surgical pain.

   Stage

   Phase 4

   Ages

   18 and older

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT03230565 on ClinicalTrials.gov

7. Opioid Dispenser for Microdiscectomy/Laminectomy

   The opioid crisis continues to plague the United States. While great strides have been made nationwide to decrease overprescribing, improvements are still needed to appropriately educate patients on the safe and responsible use, storage and disposal of opioids. Pain after surgery is often treated w…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hospital for Special Surgery, New York, New York

   Run by

   Hospital for Special Surgery, New York

   See if you can join NCT06358040 on ClinicalTrials.gov

8. Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

   The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.

   Stage

   Phase 4

   Ages

   3 to 17

   Site

   Duke University Medical Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06576830 on ClinicalTrials.gov

9. Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children

   The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery. We hypothesize that patients who are given gabapentin will need fewer morphine equivalents postoperatively than those who were not …

   Stage

   Phase 2

   Ages

   Up to 17

   Site

   UC Davis Medical Center, Sacramento, California

   Run by

   University of California, Davis

   See if you can join NCT04724252 on ClinicalTrials.gov

10. Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy

    The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation. The research team is conducting this study to determine if cryoablation provides more effective pain control when compared to an epidur…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Michigan, Ann Arbor, Michigan

    Run by

    University of Michigan

    See if you can join NCT06384664 on ClinicalTrials.gov

11. Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

    During breast surgery, sensory nerves are cut which may lead to reduced sensation and pain. Surgical reinnervation techniques have been developed with the aim of improving postoperative sensation by preserving the nerves and connecting them to the nipple and areola. The investigators aim to compare…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT06094257 on ClinicalTrials.gov

12. Depo-Medrol on Psoas After LLIF

    The goal of this study is to determine the effects of a corticosteroid administered to the psoas muscle following a transpsoas lateral lumbar interbody fusion (LLIF) on postoperative hip flexor weakness and thigh pain and numbness.

    Stage

    Phase 4

    Ages

    18 to 75

    Site

    UConn Health, Farmington, Connecticut

    Run by

    Hardeep Singh

    See if you can join NCT05929755 on ClinicalTrials.gov

13. Comparison of Methods for Recording Post Operative Pain

    The purpose of the current study is to identify the optimal method of collection of pain intensity data. The study will compare three collection methods: a hand-written pain journal, a smartphone app, and a novel electronic pain recorder device. Patients will be randomly assigned to one of three me…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Zuckerberg San Francisco General Hospital, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT06206148 on ClinicalTrials.gov

14. Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

    This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries. The investigators hypothesize that receipt of acetaminophen, celecoxib and gabapentin preoperatively versus acetaminophen alone …

    Stage

    Phase 4

    Ages

    Any age

    Site

    Northwell Health South Shore Surgery Center, Bay Shore, New York

    Run by

    Northwell Health

    See if you can join NCT06379425 on ClinicalTrials.gov

15. Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

    The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the additio…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Loyola University Chicago, Maywood, Illinois

    Run by

    Loyola University

    See if you can join NCT05824832 on ClinicalTrials.gov

16. Scheduled or As Needed Pain Regimen?

    The aim of this study is to determine feasibility of a randomized controlled trial and estimates of efficacy for pain control of a scheduled pain regimen versus an as needed pain regimen for participants undergoing same day surgery procedures.

    Stage

    Phase 4

    Ages

    18 to 65

    Site

    Cape Fear Valley Medical Center, Fayetteville, North Carolina

    Run by

    Cape Fear Valley Health System

    See if you can join NCT06495632 on ClinicalTrials.gov

17. Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

    Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly. This is especially true in patients with cerebral palsy (CP), who often have concomitant developmental delay, intellectual disability…

    Stage

    Phase 4

    Ages

    Up to 18

    Site

    Orthopaedic Institute for Children, Los Angeles, California

    Locations

    4 in total

    Run by

    University of California, Los Angeles

    See if you can join NCT06189781 on ClinicalTrials.gov