Overweight and Obesity Clinical Trials

33 studies are recruiting for overweight and obesity in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Optimal Digital Weight Loss Treatment for Rural Individuals

   Over 130 million adults in the US experience overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases. Although lifestyle interventions successfully produce clinically significant weight losses, the availability of weight management…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of South Carolina, Columbia, South Carolina

   Run by

   University of South Carolina

   See if you can join NCT06105957 on ClinicalTrials.gov

2. Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

   Obesity has become an important public health issue that leads to insulin resistance, diabetes, hypertension, dyslipidemia, and cardiovascular diseases. Although weight loss with calorie restriction and increased physical activity improve these complications, many people fail these lifestyle interv…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06069622 on ClinicalTrials.gov

3. Social Determinants and a Diabetes Prevention Program Tailored for African Americans

   African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that s…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Missouri-Kansas City, Kansas City, Missouri

   Locations

   2 in total

   Run by

   University of Missouri, Kansas City

   See if you can join NCT05301413 on ClinicalTrials.gov

4. Food Prescriptions to Promote Affordable Diets

   This is an Randomized controlled trial (RCT) to assess the impact of meal planning and affordable grocery delivery on weight loss, dietary quality and health on members of multigenerational Latino households.

   Stage

   Phase 3

   Ages

   2 and older

   Site

   Kaiser Permanente, Pasadena, California

   Run by

   Kaiser Permanente

   See if you can join NCT05309395 on ClinicalTrials.gov

5. Lifestyle Intervention for Healthy Change

   The purpose of this study is to determine the effectiveness of a physician led, multi-disciplinary approach to treating obesity that incorporates nutrition (mainly, using genetics to identify appropriate food intake), exercise, and motivational counseling. The investigators plan to recruit overweig…

   Stage

   Not phased

   Ages

   18 to 40

   Site

   Augusta University, Augusta, Georgia

   Run by

   Augusta University

   See if you can join NCT05956574 on ClinicalTrials.gov

6. Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity

   Obesity, affecting 40% of US adults and costing 173b annually, represents a significant health care burden (1). It is associated with increased risk for multiple chronic diseases including hypertension, type 2 diabetes (T2D), cardiovascular disease, and NAFLD, as well as cancer, osteoarthritis, and…

   Stage

   Phase 2

   Ages

   18 to 70

   Site

   Clinical and Translational Research Unit, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT05912621 on ClinicalTrials.gov

7. A Pilot Factorial Trial of an Integrated Lifestyle Intervention

   This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Colorado Anschutz Medical Campus, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT06116435 on ClinicalTrials.gov

8. Control Systems Engineering for Weight Loss Maintenance

   This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance using behavioral, psychosocial, and environmental indicators evaluated in a system identification experiment. A 6-month behavioral obesity trea…

   Stage

   Phase 2

   Ages

   18 to 70

   Site

   Miriam Hospital Weight Control and Diabetes Resarch Center, Providence, Rhode Island

   Run by

   The Miriam Hospital

   See if you can join NCT06244888 on ClinicalTrials.gov