Osteosarcoma Clinical Trials in Philadelphia, Pennsylvania

5 studies are recruiting for osteosarcoma in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

    This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small round cell tumor (DSRCT) that is newly diagnosed or has come back after a period of improvement (recurrent) or that has not responded to prev…

    Stage
    Phase 2
    Ages
    12 to 39
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    29 in total
    Run by
    National Cancer Institute (NCI)

    See if you can join NCT04616560 on ClinicalTrials.gov

  2. Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

    The purpose of this study is to better understand how safe and effective the drug cabozantinib in combination with high-dose ifosfamide is in the treatment of children and adults with relapsed/refractory sarcomas.

    Stage
    Phase 1
    Ages
    5 to 40
    Site
    Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    Locations
    4 in total
    Run by
    Children's Hospital of Philadelphia

    See if you can join NCT06156410 on ClinicalTrials.gov

  3. Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

    This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through …

    Stage
    Phase 3
    Ages
    Up to 50
    Site
    Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
    Locations
    233 in total
    Run by
    Children's Oncology Group

    See if you can join NCT05235165 on ClinicalTrials.gov

  4. SPEARHEAD-3 Pediatric Study

    This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.

    Stage
    Phase 1
    Ages
    2 to 21
    Site
    Children's Hospital of Philedephia, Philadelphia, Pennsylvania
    Locations
    10 in total
    Run by
    USWM CT, LLC

    See if you can join NCT05642455 on ClinicalTrials.gov

  5. Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

    This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in the laboratory from patients receiving dexrazoxane hydrochloride may help doctors learn more about the effects of …

    Stage
    Not phased
    Ages
    Any age
    Site
    Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania
    Locations
    79 in total
    Run by
    Children's Oncology Group

    See if you can join NCT01790152 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.