Osteosarcoma Clinical Trials in Boston, Massachusetts

5 studies are recruiting for osteosarcoma in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

   This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small round cell tumor (DSRCT) that is newly diagnosed or has come back after a period of improvement (recurrent) or that has not responded to prev…

   Stage

   Phase 2

   Ages

   12 to 39

   Site

   Dana-Farber Cancer Institute, Boston, Massachusetts

   Locations

   29 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT04616560 on ClinicalTrials.gov

2. Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

   This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through …

   Stage

   Phase 3

   Ages

   Up to 50

   Site

   Massachusetts General Hospital Cancer Center, Boston, Massachusetts

   Locations

   233 in total

   Run by

   Children's Oncology Group

   See if you can join NCT05235165 on ClinicalTrials.gov

3. SPEARHEAD-3 Pediatric Study

   This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.

   Stage

   Phase 1

   Ages

   2 to 21

   Site

   Dana Farber Cancer Institute, Boston, Massachusetts

   Locations

   10 in total

   Run by

   USWM CT, LLC

   See if you can join NCT05642455 on ClinicalTrials.gov

4. Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

   This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in the laboratory from patients receiving dexrazoxane hydrochloride may help doctors learn more about the effects of …

   Stage

   Not phased

   Ages

   Any age

   Site

   Dana-Farber Cancer Institute, Boston, Massachusetts

   Locations

   79 in total

   Run by

   Children's Oncology Group

   See if you can join NCT01790152 on ClinicalTrials.gov

5. Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

   This research is being done to test a new drug called PEEL-224 in combination with two commercially available drugs, Vincristine and Temozolomide, and to determine how effective this combination of drugs is at treating Ewing Sarcoma (EWS) and Desmoplastic Small Round Cell Tumor (DSRCT), as well as …

   Stage

   Phase 1

   Ages

   12 to 49

   Site

   Dana-Farber Cancer Institute, Boston, Massachusetts

   Locations

   3 in total

   Run by

   David S Shulman, MD

   See if you can join NCT06709495 on ClinicalTrials.gov