Obstructive Sleep Apnea Clinical Trials in Cincinnati, Ohio

6 studies are recruiting for obstructive sleep apnea in Cincinnati, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

   The overall objective of this randomized clinical trial is to test the effectiveness of a personalized approach to the surgical treatment of OSA in children with Down syndrome (DS).The estimated prevalence of obstructive sleep apnea (OSA) in children with DS ranges from 45-83%, compared to 1-6% in …

   Stage

   Not phased

   Ages

   2 to 17

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Locations

   7 in total

   Run by

   Oregon Health and Science University

   See if you can join NCT05508971 on ClinicalTrials.gov

2. Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

   This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are not on PAP therapy and are living with overweight or obesity.

   Stage

   Phase 3

   Ages

   18 to 99

   Site

   CTI Clinical Research Center, Cincinnati, Ohio

   Locations

   57 in total

   Run by

   Amgen

   See if you can join NCT07226765 on ClinicalTrials.gov

3. Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

   This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are receiving positive airway pressure (PAP) therapy and are living with overweight or obesity.

   Stage

   Phase 3

   Ages

   18 to 99

   Site

   CTI Clinical Research Center, Cincinnati, Ohio

   Locations

   61 in total

   Run by

   Amgen

   See if you can join NCT07225686 on ClinicalTrials.gov

4. Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

   To create a validated computational tool to predict surgical outcomes for pediatric patients with obstructive sleep apnea (OSA). The first line of treatment for children with OSA is to remove their tonsils and adenoids; however, these surgeries do not always cure the patient. Another treatment, con…

   Stage

   Phase 4

   Ages

   3 to 18

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT04991389 on ClinicalTrials.gov

5. Down Syndrome Obstructive Sleep Apnea

   The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) with moderate to severe Obstructive Sleep Apnea (OSA).

   Stage

   Phase 2

   Ages

   5 to 18

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   7 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06043440 on ClinicalTrials.gov

6. Pediatric Post-Approval Registry

   This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe obstructive sleep apnea (OSA). Implanted subjects will be followed for 5 ye…

   Stage

   Not phased

   Ages

   18 to 21

   Site

   Cincinnati Childrens Hospital, Cincinnati, Ohio

   Locations

   8 in total

   Run by

   Inspire Medical Systems, Inc.

   See if you can join NCT04457154 on ClinicalTrials.gov