Obstructive Sleep Apnea Clinical Trials in Boston, Massachusetts

7 studies are recruiting for obstructive sleep apnea in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral Pharyngeal Collapse

   The goal of this clinical trial is to learn whether removing the tonsils at the time of hypoglossal nerve stimulation improves treatment of obstructive sleep apnea in adults whose airway collapses from the side of the upper airway during sleep. The main questions it aims to answer are: 1. Does hypo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT07724938 on ClinicalTrials.gov

2. Rescue Pharmacotherapy for OSA

   Persistent obstructive sleep apnea (OSA) is common in people treated with mandibular advancement device (MAD) or hypoglossal nerve stimulation (HGNS). For most patients, these treatments are the last line of defense. If MAD or HGNS do not work, then patients are left to suffer the consequences of u…

   Stage

   Phase 1

   Ages

   21 to 70

   Site

   Sleep Disorders Research Program Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT05293600 on ClinicalTrials.gov

3. Atomoxetine and DAW2022 on OSA Severity

   Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. In previous research atomoxetine and oxybutynin showed promising effect at reducing OSA severity, however they reduced arousal threshold, one of the key traits responsible for OSA. Since oxy…

   Stage

   Phase 1

   Ages

   21 to 70

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT05350215 on ClinicalTrials.gov

4. Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

   This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS. Clinical data (MRI, lab results, medical history, labs, and sleep studies) of MS patients will be collected an…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Beth Israel Deaconess Medical Center

   See if you can join NCT04603196 on ClinicalTrials.gov

5. OurSleepKit To Support CPAP Adherence

   The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstructive sleep apnea (OSA). Participants include newly diagnosed patients with OSA who are candidates fo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northeastern University, Boston, Massachusetts

   Locations

   2 in total

   Run by

   National Heart, Lung, and Blood Institute (NHLBI)

   See if you can join NCT06621511 on ClinicalTrials.gov

6. Trazodone on OSA Endotypes

   Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for spontaneous upper airway (UA) dilator muscle recruitment. As a consequen…

   Stage

   Phase 1

   Ages

   21 to 70

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06286189 on ClinicalTrials.gov

7. Pharmacological Activation of HMN for OSA Aim 2

   Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon leads to increased collapsibility of UA compared to normal subjects. In t…

   Stage

   Phase 1

   Ages

   18 to 70

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT03858751 on ClinicalTrials.gov