Obesity Clinical Trials in Lexington, Kentucky

8 studies are recruiting for obesity in Lexington, Kentucky right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

   This trial will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF hospitalizations and urgent HF visits, cardiovascular (CV) deaths and improvement in HF symptoms in participants with HF with preserved ejection frac…

   Stage

   Phase 3

   Ages

   18 to 99

   Site

   The Research Group of Lexington LLC, Lexington, Kentucky

   Locations

   657 in total

   Run by

   Amgen

   See if you can join NCT07037459 on ClinicalTrials.gov

2. A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

   The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo in participants with persistent obesity or overweight, with or without type 2 diabetes, and on stable incretin background therapy. Participation in the study will last about 80 weeks.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   AMR Clinical, Lexington, Kentucky

   Locations

   187 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07392190 on ClinicalTrials.gov

3. A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

   The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight. Participants will either get cagrilintide, the active study medicine being tested or placebo, a medicine that has no active medicine in it. Whic…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   The Alliance for Multispecialty Research LLC AMR, Lexington, Kentucky

   Locations

   36 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT07745504 on ClinicalTrials.gov

4. The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

   The investigator hypothesizes that treatment with the ß3 agonist mirabegron results in improved glucose metabolism, including a reversal of prediabetes in obese, insulin-resistant human research participants, and this is further improved by combination therapy with tadalafil. The investigator will …

   Stage

   Phase 4

   Ages

   35 to 65

   Site

   University of Kentucky, Lexington, Kentucky

   Run by

   Philip Kern

   See if you can join NCT05051436 on ClinicalTrials.gov

5. A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

   This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe and effective CagriSema is for body weight loss in these participants. Participants will receive eit…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   The Research Group of Lexington LLC, Lexington, Kentucky

   Locations

   303 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT07564414 on ClinicalTrials.gov

6. A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

   This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo. The purpose of this clinical study is to f…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   The Research Group of Lexington LLC, Lexington, Kentucky

   Locations

   838 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT07567001 on ClinicalTrials.gov

7. Cannabis for Obesity Trial

   The goal of this study is to determine the initial efficacy of once daily oral cannabis for weight loss in obese individuals.

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   University of Kentucky, Lexington, Kentucky

   Run by

   Joshua A. Lile, Ph.D.

   See if you can join NCT06137365 on ClinicalTrials.gov

8. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

   The purpose of this study is to evaluate the safety and tolerability of single and multiple subcutaneous (SC) doses of MBX 4291 in adults with obesity.

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   MBX Biosciences Investigational Site, Lexington, Kentucky

   Locations

   4 in total

   Run by

   MBX Biosciences

   See if you can join NCT07142707 on ClinicalTrials.gov