Myasthenia Gravis Clinical Trials in Columbus, Ohio

5 studies are recruiting for myasthenia gravis in Columbus, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

   This study is part of the ADAPT Forward platform study (NCT07294170). ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects a…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Ohio State Martha Morehouse Outpatient Care, Columbus, Ohio

   Locations

   32 in total

   Run by

   argenx

   See if you can join NCT07284420 on ClinicalTrials.gov

2. ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

   ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Ohio State Martha Morehouse Outpatient Care, Columbus, Ohio

   Locations

   35 in total

   Run by

   argenx

   See if you can join NCT07294170 on ClinicalTrials.gov

3. Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

   This Phase 2 proof-of-concept, dose range finding study aims to evaluate the safety and efficacy of 3 dose levels of NMD670 vs placebo in adult patients with MG with antibodies against AChR or MuSK, administered twice a day (BID) for 21 days.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   The Ohio State University, Columbus, Ohio

   Locations

   40 in total

   Run by

   NMD Pharma A/S

   See if you can join NCT06414954 on ClinicalTrials.gov

4. A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

   The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG). The purpose of the subcutaneous substudy is to evaluate how well it works in the body (pharmacodynamic [PD]) when given as an injection under…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   The Ohio State University, Columbus, Ohio

   Locations

   112 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT04951622 on ClinicalTrials.gov

5. A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

   A Phase 1 dose-escalation study designed to evaluate the safety, tolerability, and preliminary efficacy of anito-cel in subjects with generalized myasthenia gravis (GMG). Anitocabtagene autoleucel (anito-cel) is a BCMA-directed CAR-T cell therapy.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Ohio State University, Columbus, Ohio

   Locations

   13 in total

   Run by

   Arcellx, Inc.

   See if you can join NCT06626919 on ClinicalTrials.gov