Multiple Sclerosis Clinical Trials in St Louis, Missouri

6 studies are recruiting for multiple sclerosis in St Louis, Missouri right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

   This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Washington University School of Medicine, St Louis, Missouri

   Locations

   52 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT03816345 on ClinicalTrials.gov

2. An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

   This trial is a Phase 1b, open-label, multi-center, clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and tolerability in adult participants with Multiple Sclerosis.

   Stage

   Phase 1

   Ages

   18 to 60

   Site

   Research Site, St Louis, Missouri

   Locations

   19 in total

   Run by

   AstraZeneca

   See if you can join NCT07224373 on ClinicalTrials.gov

3. This Study Involves a Positron Emission Tomography (PET) Scan Using a New Investigational Radioactive Tracer, [18F]-FZTA, to Detect Inflammation in the Brain. The Tracer Will be Tested in Healthy Younger Adults and Individuals With Multiple Sclerosis.

   This study involves a Positron Emission Tomography (PET) scan using a new investigational radioactive tracer, [18F]-FZTA, to detect inflammation in the brain. The tracer will be tested in healthy younger adults and individuals with Multiple Sclerosis.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Washington University in St. Louis, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT07115017 on ClinicalTrials.gov

4. A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

   The primary objective of this trial is to evaluate the safety and reactogenicity of mRNA-1195 in participants with multiple sclerosis.

   Stage

   Phase 2

   Ages

   18 to 55

   Site

   Washington University School of Medicine Neurology Clinical Unit, St Louis, Missouri

   Locations

   17 in total

   Run by

   ModernaTX, Inc.

   See if you can join NCT06735248 on ClinicalTrials.gov

5. Smoldering Inflammation in MS

   The goal of this observational study is to learn about inflammation in those with relapsing remitting Multiple Sclerosis (MS). The main questions it aims to answer are: * How does abnormal neural inflammation compare to cellular and molecular inflammation in MS? * Once treated, why does abnormal in…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Barnes Jewish Center for Clinical Imaging Research, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT06591429 on ClinicalTrials.gov

6. Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis

   The goal of this clinical trial is to treat male and female participants with two types of Multiple Sclerosis (MS) called primary progressive or secondary progressive MS. The main questions the trial aims to answer are the following: * Is TRX319 safe when administered to patients with progressive f…

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   Washington University, St. Louis, St Louis, Missouri

   Locations

   2 in total

   Run by

   Tr1X, Inc.

   See if you can join NCT07477639 on ClinicalTrials.gov