Mitral Regurgitation Clinical Trials in Los Angeles, California

7 studies are recruiting for mitral regurgitation in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Cephea Early Feasibility Study

   The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral valve disease (including mitral regurgitation, mitral stenosis and mixed mitral valve disease) in whom transcatheter therapy is…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   22 in total

   Run by

   Abbott Medical Devices

   See if you can join NCT05061004 on ClinicalTrials.gov

2. Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

   CASSINI-US is a prospective, single-arm, multicenter early feasibility study enrolling up to 15 patients at up to 5 sites in the United States (US). The purpose of the study is to evaluate the technical (implant) feasibility, and safety, and performance of the SATURN TS TMVR System for the treatmen…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   5 in total

   Run by

   InnovHeart

   See if you can join NCT07130994 on ClinicalTrials.gov

3. ATLAS (AltaValve) Pivotal Trial

   This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   58 in total

   Run by

   4C Medical Technologies, Inc.

   See if you can join NCT06465745 on ClinicalTrials.gov

4. CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

   This multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice. Patients evaluated for TMVR but not undergoin…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, Los Angeles, California

   Locations

   43 in total

   Run by

   Universitätsklinikum Hamburg-Eppendorf

   See if you can join NCT04688190 on ClinicalTrials.gov

5. The ENCIRCLE Trial

   This study will establish the safety and effectiveness of the SAPIEN M3 System in subjects with symptomatic, at least 3+ mitral regurgitation (MR) for whom commercially available surgical or transcatheter treatment options are deemed unsuitable. Following completion of enrollment, subjects will be …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Good Samaritan Hospital, Los Angeles, California

   Locations

   68 in total

   Run by

   Edwards Lifesciences

   See if you can join NCT04153292 on ClinicalTrials.gov

6. The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

   A prospective multicenter study enrolling high surgical risk patients with severe mitral annular calcification (MAC) and symptomatic mitral valve dysfunction (severe stenosis, ≥ moderate to severe regurgitation, or mixed ≥ moderate stenosis and ≥ regurgitation). There are 2 Arms in this study: 1) "…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   17 in total

   Run by

   Mayra Guerrero

   See if you can join NCT04408430 on ClinicalTrials.gov

7. An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

   Study to evaluate the feasibility, safety and performance of the HighLife trans-septal Transcatheter Mitral Valve in patients with moderate-severe and severe mitral regurgitation who are at high risk for surgical treatment.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Los Robles Regional Medical Center, Los Angeles, California

   Locations

   10 in total

   Run by

   HighLife SAS

   See if you can join NCT04029337 on ClinicalTrials.gov