Mild Traumatic Brain Injury Clinical Trials

30 studies are recruiting for mild traumatic brain injury in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

   Many combat veterans (c-Vs), service members (SMs) and civilians with mild traumatic brain injury (mTBI, also termed concussion) suffer from persistent post-concussion symptoms (PPCS) that degrade physical and cognitive well-being and have been linked with early neurodegeneration. PPCS include soma…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Virginia Commonwealth University, Richmond, Virginia

   Run by

   Virginia Commonwealth University

   See if you can join NCT07071350 on ClinicalTrials.gov

2. Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)

   A two site, 2-arm, Phase III randomized pragmatic clinical trial evaluating the effectiveness of quetiapine monotherapy in comparison to Treatment As Usual (TAU) medication management for symptoms experienced by veterans receiving rehabilitation therapy for mild traumatic brain injury (mTBI) and co…

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   New Mexico VA Healthcare System, Albuquerque, New Mexico

   Locations

   2 in total

   Run by

   Foundation for Advancing Veterans' Health Research

   See if you can join NCT06333990 on ClinicalTrials.gov

3. Regulation of Emotion, Sleep Extension, and mTBI

   Concussions are incredibly common, and often result in severe and long lasting symptoms, including, but not limited to, sleep deprivation and emotion dysregulation. This study aims to demonstrate the therapeutic benefits of sleep extension (napping) on emotion regulation in individuals after they s…

   Stage

   Phase 1

   Ages

   18 to 35

   Site

   Merrimack College, North Andover, Massachusetts

   Run by

   Merrimack College

   See if you can join NCT06883006 on ClinicalTrials.gov

4. Treatment Optimization of Brain-injured Warfighters

   Prescribed sub-symptomatic adaptable exercise treatment (SAET) is a potential solution that promotes recovery needs following a TBI. SAET has been shown to benefit the mind and body in ways that decrease the severity and frequency of mild TBI (mTBI) symptoms. This study aims to validate SAET as an …

   Stage

   Not phased

   Ages

   18 to 55

   Site

   Intrepid Spirit Center, Camp Pendleton, California

   Run by

   United States Naval Medical Center, San Diego

   See if you can join NCT06561100 on ClinicalTrials.gov

5. Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBI

   This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service members and civilians with mild traumatic brain injury (mTBI).

   Stage

   Phase 2

   Ages

   18 to 50

   Site

   Womack Army Medical Center - Fort Liberty, Fort Bragg, North Carolina

   Locations

   4 in total

   Run by

   Henry M. Jackson Foundation for the Advancement of Military Medicine

   See if you can join NCT05049057 on ClinicalTrials.gov