Mild Cognitive Impairment Clinical Trials

86 studies are recruiting for mild cognitive impairment in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

   The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment (MCI+) and those who are not (MCI-). AD biomarkers will be measured from …

   Stage

   Not phased

   Ages

   56 to 85

   Site

   University of Iowa Hospitals & Clinics, Iowa City, Iowa

   Run by

   Natalie Denburg

   See if you can join NCT03954899 on ClinicalTrials.gov

2. A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI

   This clinical trial is being conducted to see if brain stimulation and brain training together improves cognitive functioning and mood in older adults diagnosed with Mild Cognitive Impairment (MCI). Brain stimulation will be done using repetitive Transcranial Magnetic Stimulation (rTMS). Brain trai…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Central Arkansas VA Healthcare system, Little Rock, Arkansas

   Run by

   Central Arkansas Veterans Healthcare System

   See if you can join NCT06024473 on ClinicalTrials.gov

3. Home Sleep Therapy for Older Adults With MCI

   The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in people with mild cognitive impairment via home use sleep therapy device (SleepWISP) as well as learn about biomarkers as…

   Stage

   Not phased

   Ages

   40 to 85

   Site

   Brain Electrophysiology Laboratory Company, Eugene, Oregon

   Locations

   2 in total

   Run by

   Brain Electrophysiology Laboratory Company

   See if you can join NCT05771844 on ClinicalTrials.gov

4. tDCS for Post-Stroke Cognitive Impairment

   This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in participants with post-stroke cognitive impairment (PSCI).

   Stage

   Phase 2

   Ages

   18 to 99

   Site

   University of Oklahoma, Oklahoma City, Oklahoma

   Run by

   University of Oklahoma

   See if you can join NCT06516588 on ClinicalTrials.gov

5. Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

   Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per sec…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Andrey Vyshedskiy, Miami, Florida

   Run by

   Alzheimer's Light LLC

   See if you can join NCT03657745 on ClinicalTrials.gov

6. Longitudinal Cognitive Assessment by BoCA

   The Boston Cognitive Assessment (BoCA) is a self-administered online test intended for longitudinal cognitive monitoring. BoCA uses random not-repeating tasks to minimize learning effects. BoCA was developed to evaluate the effects of treatment in longitudinal clinical trials and available gratis t…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Andrey Vyshedskiy, Miami, Florida

   Run by

   Alzheimer's Light LLC

   See if you can join NCT04114994 on ClinicalTrials.gov

7. Natives Engaged in Alzheimers Research - 'Ike Kupuna

   This study will conduct a group randomized trial to test the effects of a hula-based intervention in improving vascular risk factors for ADRD and cognitive complaints and function over 12 months.

   Stage

   Not phased

   Ages

   50 to 75

   Site

   Kula No Na Po'e, Honolulu, Hawaii

   Locations

   3 in total

   Run by

   University of Hawaii

   See if you can join NCT05534607 on ClinicalTrials.gov

8. Paper-Based and Smartphone-Based Memory Supports

   Alzheimer's disease and related dementias lead to marked declines in daily functioning, independence, and quality of life. One of the earliest cognitive changes in these conditions is impairment in prospective memory, or the ability to remember future intentions such as taking medications at a give…

   Stage

   Not phased

   Ages

   50 and older

   Site

   UT Health Austin Comprehensive Memory Center, Austin, Texas

   Locations

   3 in total

   Run by

   Baylor University

   See if you can join NCT06444841 on ClinicalTrials.gov

9. CogT pSOPT Intervention Study

   (JUSTIFICATION: This is the R33 stage of an NIH funded R21/R33 study. R21 stage (IRB-61727) was focused on intervention development; R33 stage will focus on pilot testing the effect of the intervention. The R21 phase was not considered a NIH defined clinical trial; R33 will be considered a NIH defi…

   Stage

   Phase 1

   Ages

   60 and older

   Site

   CogT Lab, Stanford University, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT06005038 on ClinicalTrials.gov

10. Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

    This randomized controlled trial will evaluate the impact of an Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) intervention on sleep and the extent to which it contributes to cognitive health in individuals with mild cognitive impairment. Participants with insomnia who meet th…

    Stage

    Phase 2

    Ages

    65 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT05565833 on ClinicalTrials.gov

11. DC Longitudinal Study on Aging and Specimen Bank

    The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. Further, this study is assessing longitudinal …

    Stage

    Not phased

    Ages

    45 and older

    Site

    Georgetown University Memory Disorders Program, Washington D.C., District of Columbia

    Run by

    Georgetown University

    See if you can join NCT03702907 on ClinicalTrials.gov