Low Back Pain Clinical Trials

31 studies are recruiting for low back pain in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Endogenous Opioid Response to Injections

   This study will study pain relief after spine injections that are used to guide care. Some improvements in pain from a procedure might be from placebo effect rather than the physiological effect of the procedure. The study will use naloxone to reverse the effect of the body's internal placebo syste…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   VA Tennessee Valley Healthcare System, Nashville, Tennessee

   Run by

   Middle Tennessee Research Institute

   See if you can join NCT06666621 on ClinicalTrials.gov

2. Is Conditioned Pain Modulation Predictive of Clinical Improvement in Patients With Chronic Low Back Pain?

   Conditioned pain modulation (CPM) a measure of the effectiveness of the descending pain pathway and therefore a measure of the body's ability to perform endogenous analgesia. In subjects with normal function of the descending pain pathway, the net-effect during CPM testing is anti-nociceptive, or i…

   Stage

   Not phased

   Ages

   18 to 64

   Site

   Brooke Army Medical Center, Fort Sam Houston, Texas

   Run by

   Brooke Army Medical Center

   See if you can join NCT06544525 on ClinicalTrials.gov

3. Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

   SpineZone is an innovative physical therapy program with its focus on treatment of cervical, thoracic, and lumbar conditions through the use of a multi-disciplinary, technology enabled platform. Standard physical therapy modalities including psychologically informed physical therapy are employed in…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   SpineZone, San Diego, California

   Run by

   SpineZone Medical Fitness, Inc

   See if you can join NCT04081896 on ClinicalTrials.gov

4. Development and Evaluation of Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain (CBOT-P)

   The overarching goal of this study phase, Phase II component is to perform a randomized clinical trial of the refined Computerized Chemosensory-Based Orbitofrontal Networks Training for Treatment of Pain [CBOT-Pain (or CBOT-P)] from Phase I, compared to sham Computerized Chemosensory-Based Orbitofr…

   Stage

   Phase 2

   Ages

   18 to 85

   Site

   Howard University, Washington D.C., District of Columbia

   Locations

   2 in total

   Run by

   Evon Medics LLC

   See if you can join NCT06671132 on ClinicalTrials.gov

5. Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

   This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.

   Stage

   Phase 1

   Ages

   20 and older

   Site

   R3 Anti Aging Scottsdale, Scottsdale, Arizona

   Locations

   4 in total

   Run by

   R3 Stem Cell

   See if you can join NCT06361485 on ClinicalTrials.gov

6. Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial

   Rationale: Low back pain (LBP), or myofascial pain syndrome (MPS) of the low back, accounts for approximately 2.63 million visits in the United States, or 2.3 percent of annual Emergency Department (ED) visits. An estimated 100 billion dollars per year is lost from LBP. Approximately one-third of t…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   Department of Emergency Medicine, Madigan Army Medical Center, Tacoma, Washington

   Run by

   Madigan Army Medical Center

   See if you can join NCT04704297 on ClinicalTrials.gov