Liver Cancer Clinical Trials

35 studies are recruiting for liver cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

   The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpos…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Allegheny Health Network, Pittsburgh, Pennsylvania

   Locations

   18 in total

   Run by

   UMC Utrecht

   See if you can join NCT04075305 on ClinicalTrials.gov

2. Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

   This is a phase II single-arm, Phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining efficacy of riluzole in preventing cognitive dysfunction in subjects with cancer, who are receiving chemotherapy.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Chao Family Comprehensive Cancer Center, University of California Irvine, Orange, California

   Run by

   University of California, Irvine

   See if you can join NCT07447050 on ClinicalTrials.gov

3. Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

   This research study is studying an immunotherapy drug (pembrolizumab or KEYTRUDA) as a possible treatment for pediatric hepatocellular carcinoma or hepatocellular neoplasm not otherwise specified (HCN NOS).

   Stage

   Phase 2

   Ages

   0 to 30

   Site

   University of California San Francisco, San Francisco, California

   Locations

   5 in total

   Run by

   Allison O'Neill, MD

   See if you can join NCT04134559 on ClinicalTrials.gov

4. Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

   Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL). Therapeutic virtual reality (VR) has emerged as a promising and evidence-based treatme…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Run by

   Cedars-Sinai Medical Center

   See if you can join NCT04907643 on ClinicalTrials.gov

5. Biobank for Cholestatic Liver Diseases.

   This study is a biobank of specimens and clinical data for use in current and future research to better understand the cholestatic liver diseases primary biliary cirrhosis/cholangitis (PBC) and primary sclerosing cholangitis (PSC).

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Mayo Clinic, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT03445585 on ClinicalTrials.gov

6. REGULUS: MRI-guided Adaptive SABR for Liver Cancers

   Single arm unblinded study of simulation-free MRI-guided SABR with adaptive replanning in one session for treatment of patients with liver cancers

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Stanford University, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT07223307 on ClinicalTrials.gov

7. Sample Collection for Ongoing Research and Product Evaluation Study

   The SCORE study is a prospective, multi-site clinical trial designed to collect blood and tissue samples, along with relevant clinical data, from participants diagnosed with various solid tumors. The collected specimens and information will be used to evaluate the clinical performance of Natera's m…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Natera, Inc., Austin, Texas

   Run by

   Natera, Inc.

   See if you can join NCT07318051 on ClinicalTrials.gov

8. vGRID SBRT: A Phase I Clinical Trial in Unresectable or Metastatic HCC

   This trial will provide the maximum tolerated dose for radiation therapy for liver tumors and describe the toxicity profile using the vGRID therapy technique. Based on trials using this type of radiation in other cancers demonstrating low toxicity rates even with very high radiation doses and high …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   University of Kansas Medical Center

   See if you can join NCT05727787 on ClinicalTrials.gov

9. Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients

   This is a research study to evaluate change in Quality of Life, as defined by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 (EORTC C-30), from baseline to 1 month post treatment in two patient cohorts receiving Interventional Radiology Liver Di…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Durham Veterans Administration Health Care System (DVAHCS), Durham, North Carolina

   Locations

   2 in total

   Run by

   Duke University

   See if you can join NCT04933435 on ClinicalTrials.gov

10. Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors

    This research study aims to evaluate the safety and determine the optimal dose of a new experimental drug, vvDD-hIL2 (vaccinia virus double-deleted human interleukin 2), in patients with advanced abdominal cancer. The study will involve three dose levels, with three to six patients enrolled at each…

    Stage

    Phase 1

    Ages

    18 to 69

    Site

    AHN West Penn Hospital, Pittsburgh, Pennsylvania

    Run by

    Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

    See if you can join NCT07001592 on ClinicalTrials.gov