Knee Osteoarthritis Clinical Trials in Chicago, Illinois

9 studies are recruiting for knee osteoarthritis in Chicago, Illinois right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Genicular Artery Embolization for Knee Osteoarthritis

   Patients will be asked to take part in this research study because they have mild-to-moderate knee osteoarthritis (OA) and were referred clinically for a procedure called Genicular Artery Embolization (GAE). Osteoarthritis is the most common form of arthritis. It occurs when the protective cartilag…

   Stage

   Not phased

   Ages

   40 to 80

   Site

   Northwestern University, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT07537153 on ClinicalTrials.gov

2. Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis

   The goal of this study is to create a prospective registry (<100 patients) to show the effectiveness of the genicular artery embolization procedure overtime in reducing bilateral or unilateral osteoarthritic knee pain as measured by Western Ontario and McMaster Universities Osteoarthritis Index (WO…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago Duchossois Center for Advanced Medicine, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06781463 on ClinicalTrials.gov

3. ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA

   The aim of this study is to conduct a comparative evaluation of the ROAM OA Single Upright Brace and the Ossur Unloader One Knee Brace in subjects with medial compartment osteoarthritis. The focus is on comparing the immediate and short-term biomechanical effects of these braces on knee adduction m…

   Stage

   Not phased

   Ages

   40 to 85

   Site

   Rush University Medical Center, Chicago, Illinois

   Run by

   Rush University Medical Center

   See if you can join NCT07224958 on ClinicalTrials.gov

4. Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis

   This is a clinical trial of people who have pain due to knee osteoarthritis at Northwestern University Feinberg School of Medicine. The study will last for about 20 weeks. 180 qualified participants will be randomly assigned in a 1:1:1 ratio (60 participants per group) to one of three treatment gro…

   Stage

   Phase 4

   Ages

   41 and older

   Site

   Northwestern University, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT06245109 on ClinicalTrials.gov

5. A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

   This is a multicenter, prospective, randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of intra-articular administration of PTP-001 (MOTYS) for the treatment of knee osteoarthritis. The purpose of the trial is to evaluate the efficacy, safety, and tolerability of a single int…

   Stage

   Phase 3

   Ages

   40 to 80

   Site

   Chicago Clinical Research Institute, Inc., Chicago, Illinois

   Locations

   17 in total

   Run by

   Doron Therapeutics Inc.

   See if you can join NCT07219771 on ClinicalTrials.gov

6. Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty

   Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA of…

   Stage

   Not phased

   Ages

   21 to 79

   Site

   Northwestern Medicine, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT06617871 on ClinicalTrials.gov

7. Investigating Patient Satisfaction With Smart Knee Implants

   The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the Area Deprivation Index, ADI) and their recovery after knee replacement surgery, as tracked through remote monitoring. A secondary goal is t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The University of Chicago Medical Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06968143 on ClinicalTrials.gov

8. Ischemic Preconditioning in Osteoarthritis and Back Pain

   We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.

   Stage

   Not phased

   Ages

   50 and older

   Site

   Human and Sport Performance Lab, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07003113 on ClinicalTrials.gov

9. Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis

   Genicular Artery Embolization for Reducing Pain in Symptomatic Knee Osteoarthritis: A Pilot Randomized Sham-Controlled Study (SHAM-PAIN) is a NIH-NIAMS funded project designed to assess enrollment feasibility and detect any differences between GAE and a similar sham intervention in reducing KOA-rel…

   Stage

   Phase 2

   Ages

   40 to 80

   Site

   University of Chicago, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06859164 on ClinicalTrials.gov